A5030162399- Bone health and osteoporosis research
- Vitamin D Research Studies
- Estrogen and related hormone effects
- Alcohol Consumption and Health Effects
- Cancer Risks and Factors
- Global Cancer Incidence and Screening
- Peptidase Inhibition and Analysis
- Breast Cancer Treatment Studies
- Growth Hormone and Insulin-like Growth Factors
- Gout, Hyperuricemia, Uric Acid
- Cancer Treatment and Pharmacology
- Parathyroid Disorders and Treatments
- Protease and Inhibitor Mechanisms
- Liver Disease Diagnosis and Treatment
- Osteoarthritis Treatment and Mechanisms
- Nicotinic Acetylcholine Receptors Study
- Pharmacogenetics and Drug Metabolism
- Prenatal Substance Exposure Effects
- Ion channel regulation and function
- Medical Imaging Techniques and Applications
- Herpesvirus Infections and Treatments
- Traditional Chinese Medicine Studies
- COVID-19 and healthcare impacts
- Foot and Ankle Surgery
- Phosphodiesterase function and regulation
Christchurch Hospital
2024
Starship Children's Health
2021
University of Auckland
1988-2014
Royal College of Surgeons in Ireland
2011
University College Dublin
2011
Tallaght University Hospital
2011
St. Vincent's University Hospital
2011
Beaumont Hospital
2011
Mater Misericordiae University Hospital
2011
San Diego State University
2011
<h3>Objectives</h3> Recent observational studies have highlighted the beneficial role of dairy ingestion in gout prevention. The aims this study were to determine acute effects milk on serum urate concentrations and examine mechanisms these effects. <h3>Methods</h3> This was a short-term randomised controlled crossover trial 16 healthy male volunteers. following products tested (each 80 g protein): soy control, early season skim milk, late (containing high orotic acid, naturally occurring...
From 26 March 2020, New Zealand implemented a COVID-19 elimination strategy which initially involved substantive limitations on public movement and assembly, closure of non-essential businesses. We asked what effect this had acute paediatric orthopaedic presentations to tertiary children's hospital.The numbers, age gender patients with presentations, seen by either the Children's Emergency Department (CED) or service during study period, were compared equivalent 2019 period.During first 64...
Abstract Cytosol oestrogen receptor (ER) and progesterone (PR) levels were measured in tumours from three patients with breast cancer during pregnancy developing while lactating. All lactating ER‐positive two PR‐positive, whereas pregnant uniformly ER‐negative PR‐negative. Pregnant had a significantly shorter disease‐free survival compared matched nonpregnant women cancer. Of five metastatic disease, one the group complete remission chemotherapy static disease endocrine treatment, all others...
Background : The insulin‐like growth factors IGF‐I and IGF‐II their major binding protein IGFBP‐3 influence the of breast cancer cells in vitro . Some benign non‐breast tumours appear to be associated with increased serum levels which would tend reduce bioactive‐free IGF concentrations. present study investigates whether this pattern also occurs neoplastic disease. Methods Serum IGF‐I, were measured by specific radioassay 12 women disease, 31 patients age‐matched controls. Results mean (±...
Between September 1976 and May 1980, 135 patients with operable breast cancer positive axillary nodes received l-phenylalanine mustard, adjunct to surgery, 0.15 mg/kg for five days, six weekly, were randomised prospectively levamisole 150 mg three two or a placebo. Treatment was continued years until evidence of treatment failure, whichever the sooner. At 4 1/2 years, all patients, there no significant difference between groups (P = 0.09), but in subgroup women ⩽50 1–3 nodes, had negative...
Estrogen receptor status, tumor histology, and the interval between development of tumors were assessed in 99 patients with bilateral breast cancer. Tumors first grouped into those simultaneously detected both breasts or within 12 months each other (synchronous cancer, which there 64) second, more than (asynchronous 35). Nineteen percent all lobular carcinomas. Overall, rate discordance two was not significantly different from that previously reported biopsies primary metastases unilateral...
Fetal alcohol spectrum disorders (FASDs) are often characterized by symptoms of inattention and hyperactivity. Many children with FASDs receive a diagnosis attention-deficit/hyperactivity disorder (ADHD). However, it is unclear whether treatment standard stimulant medication effective in FASDs. This study evaluated response to group heavy prenatal exposure ADHD (ALC-ADHD) nonexposed (Con-ADHD). Children, aged 7–15, were assessed the QuotientTM System, which provides an objective measure...
Uncertainty regarding the timing of weight bearing following ankle open reduction internal fixation (ORIF) in patients with different fracture patterns remains. Traditional rehabilitation methods, including six weeks non-weight (NWB), is still a common approach many hospitals, while some previous evidence has shown immediate (IWB) to be beneficial.
Survival in 38 patients with bilateral breast cancer has been studied. The tumours were synchronous 14 and metachronous 24. was less than that predicted for either tumour on the basis of a previously developed index involving lymph node status, oestrogen receptor content, progesterone patient age. Simple addition indices two gave better predictor although this also overstated prospects survival both tumours. This experience suggests, therefore, or carcinoma is poor, worse might reasonably be...