A5085565516- 3D Printing in Biomedical Research
- Microfluidic and Capillary Electrophoresis Applications
- Angiogenesis and VEGF in Cancer
- Cellular Mechanics and Interactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- Laser Material Processing Techniques
- Nanopore and Nanochannel Transport Studies
- Microfluidic and Bio-sensing Technologies
- Laser Applications in Dentistry and Medicine
University of Delaware
2017-2020
Lehigh University
2019
Microfluidic devices that allow biological particle separation and concentration have found wide applications in medical diagnosis. Here we present a viral polydimethylsiloxane (PDMS) device combines tangential flow microfiltration affinity capture to enrich HIV virus single flow-through fashion. The set-up contains filtration tandem resistance channel. consists of two parallel channels separated by polycarbonate nanoporous membrane. channel, with dimensions design-guided COMSOL simulation,...
In vivo, microvasculature provides oxygen, nutrients, and soluble factors necessary for cell survival function. The highly tortuous, densely-packed, interconnected three-dimensional (3D) architecture of ensures that cells receive these crucial components. ability to duplicate microvascular in tissue-engineered models could provide a means generate large-volume constructs as well advanced microphysiological systems. Similarly, the induce realistic flow engineered is recapitulating vivo-like...