A5102953440- Cardiac Arrest and Resuscitation
- Maternal and Perinatal Health Interventions
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Meta-analysis and systematic reviews
- Trauma and Emergency Care Studies
- Statistical Methods in Clinical Trials
- Intensive Care Unit Cognitive Disorders
- Bacterial Identification and Susceptibility Testing
- Pregnancy and preeclampsia studies
- Musculoskeletal pain and rehabilitation
- Hemodynamic Monitoring and Therapy
- Pregnancy-related medical research
- Maternal and fetal healthcare
- Trauma Management and Diagnosis
- Cerebral Palsy and Movement Disorders
- COVID-19 Clinical Research Studies
- Balance, Gait, and Falls Prevention
- Mechanical Circulatory Support Devices
- Emergency and Acute Care Studies
- Healthcare Policy and Management
- Health Systems, Economic Evaluations, Quality of Life
- Assisted Reproductive Technology and Twin Pregnancy
- Optimal Experimental Design Methods
University of Warwick
2014-2025
University of Birmingham
2012-2025
Cancer Research UK Clinical Trials Unit
2012-2025
Newcastle University
2022
Great North Children's Hospital
2022
Cancer Clinic
2021
The Edgbaston Hospital
2020
Worcestershire Acute Hospitals NHS Trust
2019
Coventry (United Kingdom)
2013-2015
Princip (Czechia)
2007
ABSTRACT Background: Historically, women have been attended and supported by other during labour. However, in recent decades hospitals worldwide, continuous support labour has become the exception rather than routine. Concerns about consequent dehumanization of women's birth experiences led to calls for a return Objectives: Primary: assess effects, on mothers their babies, continuous, one‐to‐one intrapartum compared with usual care. Secondary: determine whether effects are influenced by: (1)...
Concern about the use of epinephrine as a treatment for out-of-hospital cardiac arrest led International Liaison Committee on Resuscitation to call placebo-controlled trial determine whether is safe and effective in such patients.
BackgroundMechanical chest compression devices have the potential to help maintain high-quality cardiopulmonary resuscitation (CPR), but despite their increasing use, little evidence exists for effectiveness. We aimed study whether introduction of LUCAS-2 mechanical CPR into front-line emergency response vehicles would improve survival from out-of-hospital cardiac arrest.MethodsThe pre-hospital randomised assessment a device in arrest (PARAMEDIC) trial was pragmatic, cluster-randomised...
Delirium is frequently diagnosed in critically ill patients and associated with poor clinical outcomes. Haloperidol the most commonly used drug for delirium despite little evidence of its effectiveness. The aim this study was to establish whether early treatment haloperidol would decrease time that survivors critical illness spent or coma.
Importance Patients with septic shock undergo adrenergic stress, which affects cardiac, immune, inflammatory, and metabolic pathways. β-Blockade may attenuate the adverse effects of catecholamine exposure has been associated reduced mortality. Objectives To assess efficacy safety landiolol in patients tachycardia established requiring prolonged (>24 hours) vasopressor support. Design, Setting, Participants An open-label, multicenter, randomized trial involving 126 adults (≥18...