A5083398596- Cannabis and Cannabinoid Research
- Parkinson's Disease Mechanisms and Treatments
- Restless Legs Syndrome Research
- COVID-19 and Mental Health
- Diet, Metabolism, and Disease
- Schizophrenia research and treatment
- Long-Term Effects of COVID-19
- Metabolism, Diabetes, and Cancer
- Family and Patient Care in Intensive Care Units
- Mental Health Research Topics
- Psychosomatic Disorders and Their Treatments
- Neurotransmitter Receptor Influence on Behavior
- Mental Health Treatment and Access
- Tryptophan and brain disorders
- Pharmacology and Obesity Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Federal Neuro Psychiatric Hospital
2020-2024
Stellenbosch University
2022
Objectives: Tardive dyskinesia (TD) unlike acute dystonia may be irreversible. This study investigated the effects of oral cannabidiol (CBD) on haloperidol-induced vacuous chewing movement (VCM) model TD. Methods: There were six experimental groups with different combinations 5 mg/kg haloperidol given orally. Behavioural assays and FBS measured. VCMs assessed after last dose medication. Blood for oxidative stress was collected 8th day administration Results: found that CBD co-administration...
Prior research has highlighted the psychosocial impact of infectious diseases on individuals and community at large. However, little is known about implications COVID-19. This study set out to determine rate as well correlates anxiety depressive symptoms among persons managed in-patients for COVID-19 in Lagos, Nigeria.We conducted an online survey between April June ending 2020 using a consecutive sampling technique positive who were across five (5) treatment centres Nigeria. The collected...
Abstract Atypical antipsychotics, despite their rapid dissociation from dopamine receptors and reduced tendency to induce oxidative stress, have been associated with difficult-to-manage movement disorders, including tardive dyskinesia (TD). The study set out investigate the effects of cannabidiol (CBD), a potent antioxidant, on risperidone-induced behavioural motor disturbances; namely vacuous chewing movements (VCM), stress markers (e.g. superoxide dismutase (SOD), catalase (CAT),...
Abstract Objectives: We investigated the influence of oral cannabidiol (CBD) on vacuous chewing movements (VCM) and oxidative stress parameters induced by short- long-term administration haloperidol in a rat model tardive dyskinesia (TD). Methods: Haloperidol was administered either sub-chronically via intraperitoneal (IP) route or chronically intramuscular (IM) to six experimental groups only combination with CBD. VCM were assessed at different time points after last dose medication....
The duration of administration (e.g., subchronic or chronic) haloperidol may influence its adverse effects. We studied the effects on body weight and fasting blood sugar (FBS). In addition, we examined whether orally administered cannabidiol (CBD) had any putative mitigating haloperidol-induced changes FBS elevation.Haloperidol (5 mg/kg/day) was for 21 days (subchronic administration), via intraperitoneal (IP) route, monthly (50 mg/kg monthly) 3 months (chronic intramuscular (IM) either...
Abstract Background : The COVID-19 pandemic has been described to have significant effects on the mental health and emotional well-being of people all over world generally. This study aimed at describing set up functions psychosocial support service for response in Lagos South West Nigeria. Methods: A retrospective descriptive overview covid-19 patients supported Lagos, Nigeria a four-month period. Remote interventions given included Psychological first aid, counselling, psycho pharmacology,...