A5035790031- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Food Allergy and Anaphylaxis Research
- Inhalation and Respiratory Drug Delivery
- Urticaria and Related Conditions
- Neonatal Respiratory Health Research
- Analytical Chemistry and Chromatography
- Pediatric health and respiratory diseases
- Polyamine Metabolism and Applications
- Immunotherapy and Immune Responses
- Pharmacogenetics and Drug Metabolism
- Immune Cell Function and Interaction
- Lung Cancer Treatments and Mutations
- Neuropeptides and Animal Physiology
- Glutathione Transferases and Polymorphisms
- Synthesis and Biological Evaluation
- Genomics, phytochemicals, and oxidative stress
- Receptor Mechanisms and Signaling
Johns Hopkins University
1987-2017
Johns Hopkins Medicine
1990-2017
Johns Hopkins Bayview Medical Center
1987
Journal Article Expression of CYP1A1 Gene in Patients With Lung Cancer: Evidence for Cigarette Smoke-Induced Normal Tissue and Altered Regulation Primary Pulmonary Carcinomas Get access Theodore L. McLemore, McLemore * Program Development Research Group, Developmental Therapeutics Program, Division Cancer Treatment, National InstituteBethesda, Md † Correspondence to: M.D., 170 Eighth St. SE, Suite C, Paris, TX 75460 Search other works by this author on: Oxford Academic PubMed Google Scholar...
Journal Article Metabolic Activation of 4-Ipomeanol in Human Lung, Primary Pulmonary Carcinomas, and Established Carcinoma Cell Lines Get access Theodore L. McLemore, McLemore * Program Development Research Group, Developmental Therapeutics Program, Division Cancer Treatment, National Institute, Frederick CenterFrederick, Md *Correspondence to : M.D., 170 Eighth St. S.E., Ste. C, Paris, TX 75460. Search for other works by this author on: Oxford Academic PubMed Google Scholar Charles...
Allergic inflammatory processes may have the capacity to propagate systemically through actions of circulating leucocytes. Consequently, basophils from allergic individuals are often 'primed', as evidenced by their hyperresponsiveness in vitro. IFN-alpha secreted predominantly plasmacytoid dendritic cells (pDCs), suppresses basophil priming for IL-13 production vitro.This study sought vivo correlates arising during experimental allergen challenge that support an 'axis-interplay' between and...
The mechanism(s) leading to the development of late phase allergic reactions is (are) unknown. Previous studies have indicated that a relationship between serum IgE and exists. To explore relationships allergen‐specific immunoglobulins in bronchoalveolar lavage (BAL) fluids magnitude airflow limitation during response inhaled allergen. Ragweed‐specific IgE, IgA, secretory IgA (sIgA) IgG were measured BAL fluid 1–5 weeks before whole lung antigen challenge with ragweed extract, 16 asthmatics....
Allergic inflammation is a common feature of asthma and may contribute to both development perpetuation disease. The interaction antigen-presenting cells (APC) with sensitized helper T lymphocytes (TC) producing Th2 cytokines determine the inflammatory response. Recruitment APC TC lung during allergic responses has been demonstrated, but functional studies in humans have limited.This study examined function accumulating at sites after segmental allergen challenge (SAC).Fifteen patients...