A5010114439- Genetic factors in colorectal cancer
- Colorectal Cancer Treatments and Studies
- Multiple and Secondary Primary Cancers
- Colorectal and Anal Carcinomas
- Obesity, Physical Activity, Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nutritional Studies and Diet
- Cancer Genomics and Diagnostics
- Physical Activity and Health
- Colorectal Cancer Screening and Detection
- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Risk Factors
Holy Cross University
2019-2024
Abstract Despite the introduction of new molecular classifications, advanced colorectal cancer (CRC) is treated with chemotherapy supplemented anti-EGFR and anti-VEGF targeted therapy. In this study, 552 CRC cases different primary tumor locations (250 left side, 190 rectum, 112 right side) were retrospectively analyzed by next generation sequencing for mutations in 50 genes. The most frequently mutated genes TP53 left-sided tumors compared to right-sided BRAF tumors. Mutations KRAS , NRAS...
Objective The study was designed to address the following three key areas, that is, (1) evaluate overall level of physical activity in residents a mid-sized, Central-European city, (2) compliance with WHO’s recommendations on leisure time and (3) actual impact select socioeconomic factors within population. Methods Assessment source data collected for 4619 participants (1532 men 3087 women, aged 45–65 years; mean age 56.41±5.31 years) completed. Three levels activity, pertinent WHO...
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide; with age acknowledged as an independent cardiovascular risk factor (CRF) in adults. Appreciating association between and classic CRFs is believed to boost all potential benefits prevention.Assessment prevalence single clustered their age.The survey involved 4735 people (33.6% men) who were PONS project attendees aged 45-64. The study protocol comprised Health Status Questionnaire, general medical examination,...
For years, the increase in cancer incidence and deaths has constituted a significant health social problem. Variation burden cancers different regions of world requires constant monitoring epidemiological situation this regard. Assessing survival patients is valuable source information for physicians alike, as well politicians who have direct impact on shaping policy systems. The aim present study was to assess changes 5-year relative colorectal during 1995-2014.The data 8,970 with years...
Abstract Despite the introduction of new molecular classifications, advanced colorectal cancer (CRC) is treated with chemotherapy supplemented anti-EGFR and anti-VEGF targeted therapy. In this study, 552 CRC cases different primary tumor locations (250 left side, 190 rectum, 112 right side) were retrospectively analyzed by next generation sequencing for mutations in 50 genes. The most frequently mutated genes TP53 left-sided tumors BRAF right-sided tumors. Mutations KRAS , NRAS not detected...