A5101895707- Plasma Diagnostics and Applications
- Plasma Applications and Diagnostics
- Receptor Mechanisms and Signaling
- Cancer-related Molecular Pathways
- MicroRNA in disease regulation
- TGF-β signaling in diseases
- Air Quality and Health Impacts
- PI3K/AKT/mTOR signaling in cancer
- Bone health and treatments
- Energy and Environment Impacts
- Cancer-related molecular mechanisms research
- Lung Cancer Treatments and Mutations
- Nitric Oxide and Endothelin Effects
- Nanomaterials and Printing Technologies
- Circular RNAs in diseases
- Climate Change and Health Impacts
- Semiconductor Lasers and Optical Devices
- Neuropeptides and Animal Physiology
- Protein Kinase Regulation and GTPase Signaling
- Mosquito-borne diseases and control
- Electrostatic Discharge in Electronics
- Protein Hydrolysis and Bioactive Peptides
- Vector-borne infectious diseases
- Viral Infections and Vectors
Gansu Provincial Center for Disease Control and Prevention
2023-2024
Hebei Medical University
2021
Xingtai People's Hospital
2021
First Affiliated Hospital of Xi'an Jiaotong University
2020
Yantaishan Hospital
2015
Aerospace Center Hospital
2013
Shandong University
2010-2012
Xi'an Jiaotong University
2008
Introduction: The aim of this study was to investigate the effect high glucose levels on proliferation and osteogenic ability in MC3T3-E1 osteoblastic cell line explore regulatory mechanism PI3 kinase (PI3K)/Akt signaling pathway. Methods: cultures were divided into 8 treatment groups: 4 concentrations (5.5, 15.5, 25.5, 35.5 mM) with or without LY294002. Cell proliferation, alkaline phosphatase (ALP) assay, alizarin red staining mineralized nodule, genes, P-AKT expression analyzed. Results:...
Papillary Thyroid Carcinoma (PTC) represents the most common thyroid cancer. Until recently, treatment options for PTC patients are limited. Nilotinib is second-generation tyrosine kinase inhibitor, and has been widely used in of Chronic Myeloid Leukemia (CML).We aimed to explore whether nilotinib effective suppression cancer progression underlying mechanisms.In this study, three human cell lines (KTC-1, BCPAP, TPC1) were verify effects on growth. The half maximal inhibitory concentration...
Abstract Mainland China included Japanese encephalitis (JE) vaccine in the national immunization program 2008 to control JE epidemic. However, Gansu province Western experienced largest outbreak since 1958 2018. We conducted a retrospective epidemiological study explore causes of this outbreak. found that adults aged ≥20 years (especially those rural areas) were main cases Province, with significant increase incidence older ≥60 2017 and In addition, outbreaks Province mainly located...
The regulator of G‑protein signaling 2 (RGS2) has been shown to be crucial in the regulation vascular tone and blood pressure. activities adrenomedullin (ADM) adrenotension (ADT), two natural peptides, are dependent upon modulation RGS2 expression. However, effects pathways involved their remain unknown. This study aimed observe changes expression response ADM ADT cultured smooth muscle cells clarify potential vitro. In present study, (VSMCs) were with various concentrations for different...
The activation of Gq-protein-coupled receptors induces proliferation vascular smooth muscle cells (VSMCs) and is involved in remodeling. regulator G protein signaling 2 (RGS2), which accelerates the termination Gq signaling, may play a role However, this remains unclear.Aortic balloon injury or sham operation was produced male Wistar rats. Histological examination gene expression analysis were performed after surgery. In cultured VSMCs modulation RGS2 expression, cell also evaluated.At day 3...
We introduce a novel microplasma device with coplanar electrodes (Coplanar Eletrode Microplasma Devices, CEMPD). The microcavities of the proposed compose two instead dielectric or single cathode, which can enhance density microcavities. devices are fabricated by only one wet lithography process, simplify fabrication processes and develop uniformity. Two kinds prototype have been fabricated, line array CEMPD arrays CEMPD. experiments show that power loading each microcavity could reach...
Abstract Background: MicroRNAs (miRNAs) act as pivotal functions in gastric cancer (GC) carcinogenesis and progression. MiR-559 has been defined a potential suppressor gene few cancers. Nevertheless, the biological effect of miR-559 human GC underlying molecular mechanism still unclear need to be further illuminated. Methods: Quantitative real-time PCR (qRT-PCR) was fulfilled for measuring expression level GC. The dual-luciferase reporter used verify that tripartite motif-containing 14...