A5036050887- Viral gastroenteritis research and epidemiology
- Water Treatment and Disinfection
- Fecal contamination and water quality
- Legionella and Acanthamoeba research
- Infection Control and Ventilation
- Infection Control in Healthcare
- Indoor Air Quality and Microbial Exposure
- SARS-CoV-2 detection and testing
- Essential Oils and Antimicrobial Activity
- Bacteriophages and microbial interactions
- Animal Virus Infections Studies
- Food Safety and Hygiene
- Insect Pest Control Strategies
- Listeria monocytogenes in Food Safety
- Water Systems and Optimization
- Vibrio bacteria research studies
- Nanoparticles: synthesis and applications
- Occupational exposure and asthma
- Healthcare and Environmental Waste Management
- Wastewater Treatment and Reuse
- Virus-based gene therapy research
- Viral Infections and Immunology Research
- Dental Research and COVID-19
- Parvovirus B19 Infection Studies
- Bacterial biofilms and quorum sensing
University of Arizona
2014-2024
Murdoch Children's Research Institute
2020
Arizona State University
2015
Arizona Science Center
1992
To investigate the antiviral efficacy of oregano oil and its primary active component, carvacrol, against nonenveloped murine norovirus (MNV), a human surrogate. Along with an observed loss in cell culture infectivity, mechanisms action were determined side‐by‐side experiments including cell‐binding assay, RNase I protection assay transmission electron microscopy (TEM). Both antimicrobials produced statistically significant reductions (P ≤ 0·05) virus infectivity within 15 min exposure (c....
ABSTRACT The methods used to concentrate enteric viruses from water have remained largely unchanged for nearly 30 years, with the most common technique being use of 1MDS Virozorb filters followed by organic flocculation secondary concentration. Recently, a few studies investigated alternatives; however, many these are impractical in field or share some limitations this traditional method. In present study, NanoCeram virus sampler, an electropositive pleated microporous filter composed...
The presence of microorganisms on common classroom contact surfaces (fomites) was determined to identify the areas most likely become contaminated. Six elementary classrooms were divided into control and intervention groups (cleaned daily with a quaternary ammonium wipe) tested for heterotrophic bacteria. Three also norovirus influenza A virus. Frequently used fomites contaminated; water fountain toggles, pencil sharpeners, keyboards, faucet handles bacterially desktops, handles, paper towel...
Numerous plant compounds have antibacterial or antiviral properties; however, limited research has been conducted with nonenveloped viruses. The efficacies of allspice oil, lemongrass and citral were evaluated against the murine norovirus (MNV), a human surrogate. mechanisms action also examined using an RNase I protection assay, host cell binding transmission electron microscopy. All three antimicrobials produced significant reductions (P ≤ 0.05) in viral infectivity within 6 h exposure...
Germicidal ultraviolet (UV) devices have been widely used for pathogen disinfection in water, air, and on food surfaces. Emerging UV technologies, like the krypton chloride (KrCl*) excimer emitting at 222 nm, are rapidly gaining popularity due to their minimal adverse effects skin eyes compared with conventional lamps 254 opening opportunities occupied public spaces. In this study, inactivation of seven bacteria five viruses, including waterborne, foodborne respiratory pathogens, was...
Arcanobacterium (Actinomyces) pyogenes, an animal pathogen, produces a hemolytic exotoxin, pyolysin (PLO). The gene encoding PLO was cloned, and sequence analysis revealed open reading frame of 1,605 bp protein 57.9 kDa. has 30 to 40% identity with the thiol-activated cytolysins (TACYs) number gram-positive bacteria. activity found be very similar those other TACYs, except that it not thiol activated. highly conserved TACY undecapeptide is divergent in PLO; particular, cysteine residue...
Biofilms can have deleterious effects on drinking water quality and may harbor pathogens. Experiments were conducted using 100 microg/liter silver to prevent biofilm formation in modified Robbins devices with polyvinyl chloride stainless steel surfaces. No significant difference was observed either surface between the treatment control.
Naegleria fowleri is a free-living amoeba found in waters warmer regions that causes primary amoebic meningoencephalitis, rare but almost universally fatal disease. The goal of this project was to assess the occurrence N. and other thermophilic amoebae 33 recreational surface across Arizona determine if their presence could be correlated with seasonal or environmental factors. First, 1-L grab samples were collected over two years analyzed using polymerase chain reaction viability....
To determine the rate of reduction Legionella pneumophila by stainless steel surfaces with zeolite ceramic coatings containing 2.5% (w/w) silver (Ag) and 14% zinc (Zn) ions.Stainless pans without Ag/Zn were inoculated solutions Leg. ATCC 33155 incubated at 37 degrees C. Survival was monitored using spread-plate technique on selective buffered charcoal yeast extract agar. Significant reductions effected within 2 h exposure.Zeolite impart significant anti-Legionella properties to surfaces....
This study was conducted to assess the efficacy of silver as a secondary disinfectant replace or reduce level chlorine utilized in water distribution systems. Pseudomonas aeruginosa and Aeromonas hydrophila are opportunistic pathogens present drinking have been associated with waterborne disease. After 8 hours exposure 100 microg/L silver, there >6-log10 reduction P. tap at room temperature pH7 5.55-log10 presence 3 mg/L humic acid. Similar reductions were observed pH9. At 4 degrees C,...