- Gut microbiota and health
- Atherosclerosis and Cardiovascular Diseases
- Immune Cell Function and Interaction
- Inflammatory mediators and NSAID effects
- Cholesterol and Lipid Metabolism
- Diet and metabolism studies
- Cancer Immunotherapy and Biomarkers
- Extracellular vesicles in disease
- Protease and Inhibitor Mechanisms
- Systemic Sclerosis and Related Diseases
- Nitric Oxide and Endothelin Effects
- Liver Disease and Transplantation
- CAR-T cell therapy research
- Tryptophan and brain disorders
- Liver physiology and pathology
- SARS-CoV-2 and COVID-19 Research
- Respiratory viral infections research
- Inflammatory Bowel Disease
- Cancer, Lipids, and Metabolism
- Pomegranate: compositions and health benefits
- Adenosine and Purinergic Signaling
- MicroRNA in disease regulation
- Systemic Lupus Erythematosus Research
- Adipokines, Inflammation, and Metabolic Diseases
- Cell Adhesion Molecules Research
Tehran University of Medical Sciences
2020-2024
Iran University of Medical Sciences
2015-2017
Hepatic osteodystrophy, a prevalent manifestation of metabolic bone disease, can arise in the context chronic liver disease. The THBS1-eNOS-NO signaling pathway plays pivotal role maturation osteoclast precursors. This study aimed to investigate impact Naltrexone (NTX) on loss by examining pathways bile duct ligated (BDL) rats. Male Wistar rats were randomly divided into five groups (n = 10 per group): control, sham-operated + normal saline, BDL NTX (10 mg/kg), and NTX. Parameters related...
Background: The vessel restenosis is related to the inflammatory events in subendothelial space. It proposed that agents affect prostaglandin synthesis pathway. In this study, we investigated COX-1, COX-2, PTGDS and miRNA-520a-5p expression levels serum 15-Deoxy-Δ12,14-PGJ2 metabolite values patients with stenosed re-stenosed vessels. Furthermore, associations between genes miR-520 were evaluated monocyte transfection studies. Methods: subjects (n=60) included three groups; healthy (control...
Background: The vessel stenosis and re-stenosis processes are mainly related to cellular molecular events. vascular smooth muscle cell (VSMC) activation is the basic element in these lesions. Based on monocyte macrophage inflammatory responses also VSMC motility, a complex protein network dynamically proposed between cells. aim of this study was highlight communications involved proliferation migration signaling pathways. Keywords: Atherosclerosis, network, cluster, pathway, VSMC,...