Eduardo Fernández‐Martínez

ORCID: 0000-0003-3280-1323
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About
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Research Areas
  • Drug-Induced Hepatotoxicity and Protection
  • Liver Disease Diagnosis and Treatment
  • Pain Mechanisms and Treatments
  • Echinoderm biology and ecology
  • Diet, Metabolism, and Disease
  • Liver Disease and Transplantation
  • Reproductive System and Pregnancy
  • Pharmacological Effects of Natural Compounds
  • Public Health and Nutrition
  • Menstrual Health and Disorders
  • Healthcare Systems and Reforms
  • Multiple Myeloma Research and Treatments
  • Drug Transport and Resistance Mechanisms
  • Inflammatory mediators and NSAID effects
  • School Health and Nursing Education
  • Phytochemicals and Antioxidant Activities
  • Herbal Medicine Research Studies
  • Liver physiology and pathology
  • Sperm and Testicular Function
  • Diet and metabolism studies
  • Genomics, phytochemicals, and oxidative stress
  • Phosphodiesterase function and regulation
  • Cholesterol and Lipid Metabolism
  • Natural product bioactivities and synthesis
  • Lung Cancer Treatments and Mutations

Universidad Autónoma del Estado de Hidalgo
2016-2025

Center for Research and Advanced Studies of the National Polytechnic Institute
2001-2004

Context: There have been no reports of the extraction essential oil (EO) from white cabbage [Brassica oleracea L. var. capitata (L.) Alef. f. alba DC. (Brassicaceae)] (Bocfal) or its chemical composition, antioxidant activity, hepatoprotective effects.Objective: To extract Bocfal EO, to identify and quantify components, assess their capacity, evaluate properties EO.Materials methods: EO was obtained using hydrodistillation (200 mm Hg/58 °C). The composition analyzed GC-MS quantified GC-FID....

10.1080/13880209.2016.1258424 article EN cc-by Pharmaceutical Biology 2016-12-07

Pomegranate is a polyphenol-rich fruit. Studies have shown that extracts prepared from its juice or different parts of the pomegranate plant various biological activities including antioxidant, antimicrobial, anti-inflammatory, anticarcinogenic, cardioprotective, and antidiabetic. The therapeutic potential has been attributed to phytochemicals, ellagic acid, punicic flavonoids, anthocyanidins, anthocyanins, flavonols, flavones. This review focuses on scientific evidence as hypoglycemic,...

10.3390/antiox11030553 article EN cc-by Antioxidants 2022-03-15

Chia seeds (Salvia hispanica L.) are rich in omega fatty acids. Dyslipidemia and steatohepatitis diseases that require effective treatments obese non-obese patients. The aim was to evaluate the effect of chia intake on acute tyloxapol (TI)-induced dyslipidemia, carbon tetrachloride (TC)-induced steatohepatitis, mixed damage (TC+TI) rats. Four experimental groups were fed for 4 weeks a diet with established rodent food (DE), four 15% added (DC). Plasma samples analyzed total cholesterol,...

10.1111/jfbc.12986 article EN Journal of Food Biochemistry 2019-07-21

Among various phenolic compounds, caffeic acid (3,4-dihydroxycinnamic acid) exhibited pharmacological antioxidant, anticancer and antimutagenic activities. The antioxidant properties of compounds depend on their chemical structure, however, the role ethylenic side chain in radical scavenging activity remains controversial. Thus, aim this study consisted to test cinnamic 15 derivatives well known CCl4- induced acute liver damage model, which is dependent oxidative stress mechanisms. Cinnamic...

10.2174/157340607781745410 article EN Medicinal Chemistry 2007-09-01

Aloysia triphylla is traditionally utilized for the treatment of menstrual colic (primary dysmenorrhea) in Mexico. Citral main chemical component found leaves extract. Primary dysmenorrhea a very frequent gynecological disorder menstruating women, affecting 30–60% them. It usually treated with non-steroidal anti-inflammatory drugs (NSAIDs); although their effect rapid, they possess many side effects. Due to these shortcomings, Mexican folk therapy considered as feasible alternative. The...

10.1540/jsmr.46.309 article EN cc-by-nc Journal of Smooth Muscle Research 2010-01-01

The aim of this study was to compare the efficacy diclofenac, for treatment acute pain originated by lower-limb fracture and surgery, with that diclofenac plus B vitamins. This a single-center, prospective, randomized, double-blinded clinical trial. Patients closed fractures rated their on 10 cm visual analog scale (VAS). were then randomized receive or vitamins (thiamine, pyridoxine, cyanocobalamin) intramuscularly twice daily. Patient evaluations intensity recorded throughout two periods:...

10.1155/2012/104782 article EN cc-by Pain Research and Treatment 2011-10-31

Background and Objectives: To investigate the effect of infection with human papillomavirus (HPV) or Chlamydia trachomatis (CT) HPV + CT coinfection on sperm quality, inflammation, state oxidative stress (OS) in asymptomatic infertile men. Materials Methods: Semen samples from 84 military men were studied. The polymerase chain reaction (PCR) was used for molecular detection CT. parameters analyzed according to World Health Organization guidelines. Inflammation evaluated by an IL-1β, IL-6,...

10.3390/medicina57090862 article EN cc-by Medicina 2021-08-24

The endocarp of Opuntia oligacantha (xoconostle Ulapa) is composed seeds and mucilage, considered a residue. objective this article to describe the flour for food area. obtained by dehydration milling, subsequently characterized through physicochemical, nutritional, technological properties antioxidant capacity. results show that has low acidic pH (4.1 ± 0.05), humidity (7.51 0.22) aw (0.31 0.00). L*=53.67 0.71; red, a*=10.00 0.31and yellow, b*= 14.55 2.27 giving red-brown color. Low amount...

10.15741/revbio.12.e1595 article EN cc-by-nc-nd Revista Bio Ciencias 2025-04-11

Background/Objectives: Carvacrol is a naturally occurring phenolic monoterpene that one of the major constituents essential oils oregano (Origanum vulgare), thyme (Thymus vulgaris) and other herbs. has anti-inflammatory antinociceptive effects. At systemic level, carvacrol able to activate inhibit several second messengers ion channels. However, there no evidence on peripheral antinociception its probable mechanism action. The aim this study was investigate whether local involves opioid...

10.20944/preprints202504.0900.v1 preprint EN 2025-04-10

Background/Objectives: Carvacrol is a naturally occurring phenolic monoterpene that one of the main constituents essential oils oregano (Origanum vulgare) and other herbs. has anti-inflammatory antinociceptive effects. can activate inhibit several second messengers ionic channels at systemic level. However, there no evidence peripheral antinociception carvacrol its mechanism action. This study was designed to determine whether opioid receptor-nitric oxide (NO)-cyclic guanosine monophosphate...

10.3390/metabo15050314 article EN cc-by Metabolites 2025-05-07

High-risk human papillomavirus (HR-HPV) infection, followed by chronic inflammation and oxidative stress, is a major risk factor of male infertility. In this study, we explored the potential impact high-risk (HR) HPV genotypes in single infection (SI) multiple infections (MI) that promote CYP2E1 expression, damage pro-inflammatory cytokines, possibly contributing to sperm Semen samples from 101 infertile military men were studied. We analyzed seminal parameters, namely, genotyping,...

10.3390/antiox11061051 article EN cc-by Antioxidants 2022-05-26

Objective Thalidomide has anti-inflammatory, anti-tumour necrosis factor-alpha and anti-collagen activities. Cirrhosis is characterized by inflammation fibrosis. Thus, thalidomide was evaluated in an experimental model of liver cirrhosis. Methods Male Wistar rats were used. Group 1 (n = 8) received mineral oil i.p. (control); group 2 15) CCl4 for 8 weeks to induce cirrhosis; 3 consisted receiving plus (200 mg/kg/12 h); animals 4 only. Alanine aminotransferase (ALT), gamma-glutamyl...

10.1097/00042737-200309000-00003 article EN European Journal of Gastroenterology & Hepatology 2003-09-01
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