A5100742108- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Advanced Neuroimaging Techniques and Applications
- MRI in cancer diagnosis
- Lung Cancer Diagnosis and Treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Acute Ischemic Stroke Management
- Cardiovascular Health and Disease Prevention
- Radiomics and Machine Learning in Medical Imaging
- Mitochondrial Function and Pathology
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Pleural and Pulmonary Diseases
- Cardiac Imaging and Diagnostics
- Functional Brain Connectivity Studies
- Photodynamic Therapy Research Studies
- Coronary Interventions and Diagnostics
- Hemispheric Asymmetry in Neuroscience
- Intracranial Aneurysms: Treatment and Complications
- Vestibular and auditory disorders
- Traditional Chinese Medicine Studies
- Moyamoya disease diagnosis and treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Advanced X-ray and CT Imaging
- Fetal and Pediatric Neurological Disorders
- Alzheimer's disease research and treatments
Jilin University
2025
Guangxi University of Chinese Medicine
2022-2025
West Anhui University
2025
Suzhou University of Science and Technology
2025
China-Japan Friendship Hospital
2015-2024
First Affiliated Hospital of Wenzhou Medical University
2024
Wenzhou Medical University
2024
Peking University
2006-2023
Central South University
2023
Universidad del Noreste
2022
To detect white matter abnormalities in patients with mild Alzheimer disease (AD) by diffusion tensor imaging and to determine their topographic relationship gray atrophy.Thirteen AD 16 normal age-matched volunteers underwent three-dimensional spoiled gradient-recalled sequence scanning. Voxel-based morphometry was conducted regions of atrophy the group relative control group. Fractional anisotropy (FA) maps were processed using SPM2 make voxel-wise comparison whole brain between two groups....
Abstract Current analysis of diffusion tensor imaging (DTI) is based mostly on a region interest (ROI) in an image dataset, which specified by users. This method not always reliable, however, because the uncertainty manual specification. We introduce improved fiber‐based scheme rather than ROI‐based to study DTI datasets 31 normal subjects asymmetry cingulum, one most prominent white matter fiber tracts limbic system. The present can automatically extract quantitative anisotropy properties...
A noninvasive method using microscopy and spectroscopy for analysing the morphology of collagen elastin their biochemical variations in skin tissue will enable better understanding pathophysiology hypertrophic scars facilitate improved clinical management treatment this disease.To obtain simultaneously microscopic images spectra fibres ex vivo tissues (normal scar) a nonlinear spectral imaging method, to compare morphological structure characteristics scar with those normal skin, determine...
Metabolomics has proven to be a valuable tool in gaining new insights into disease progression and prognosis, the specific metabolic alterations serum of recurrent chronic rhinosinusitis with nasal polyps (CRSwNP) patients remain unknown. This study aims explore metabolomic profiles CRSwNP identify potential predictive biomarkers.A prospective, single-center was conducted on prior endoscopic sinus surgery. Serum samples were subjected untargeted profiling. Patients followed up for over 2...
Current knowledge of the collateral circulation remains sparse, and a noninvasive method to better characterize role collaterals is desirable. The aim our study was investigate presence distal flow by using new MR perfusion territory imaging, vessel-encoded arterial spin-labeling (VE-ASL).Fifty-six patients with internal carotid artery (ICA) or middle cerebral (MCA) stenosis were identified sonography. VE-ASL performed assess function flow. information combined VE maps into high...
A fiber-tracking algorithm was used to extract fractional anisotropy of bilateral cingulum bundles in patients with probable Alzheimer's disease and normal aging controls. In addition, their hippocampal volumes were measured manually. Relative controls, showed a significant reduction volumes. Significant correlation observed between values hippocampi mini-mental state examination scores. This study suggests that lower is associated cognitive dysfunction atrophy the limbic system.
An efficient and environmental method was employed to synthesize multi-substituted 2H-pyran from methyl coumalate β-keto esters or diketones. Porcine pancreas lipase (PPL) can catalyze this transformation in high yields (74–96%) aqueous medium (H2O: DMSO = 2:1) under mild conditions (60 °C). The reported strategy exhibits functional group compatibility broad substrate scope. In addition, it provides access a variety of tetra-substituted 2H-pyrans which are considered privileged scaffolds...
BACKGROUND Pancreaticobiliary maljunction (PBM) is a rare congenital abnormality in pancreaticobiliary duct development. PBM commonly found children, and it often leads to acute pancreatitis other diseases as result of reflux. Roux-en-Y choledochojejunostomy common surgical method for the treatment PBM, but there are several associated complications that may occur after this operation. CASE SUMMARY The patient, 12-year-old female, was hospitalized nearly 20 times 2021 recurrent pancreatitis....
Colorectal cancer (CRC) is one of the most common malignant tumors, characterized by a high incidence and mortality rate. Macrophages, as key immune cell type within tumor microenvironment (TME), play role in evasion progression CRC. Therefore, identifying macrophage biomarkers great significance for predicting prognosis CRC patients. This study integrates scRNA-seq bulk RNA-seq data to identify macrophage-related genes By applying comprehensive machine learning framework, prognostic...
Background The primary Sjögren's Syndrome-associated Interstitial Lung Disease (pSS-ILD) patients have a worse prognosis than pSS without pulmonary involvement. This study aims to establish prediction nomogram for early of lung transplantation (LTx)-free survival in pSS-ILD patients. Methods training cohort comprised 260 from China-Japan Friendship Hospital between January 1, 2016, and June 30, 2022, while the external validation consisted 135 Beijing Chaoyang 2007, December 31, 2012....
Multiparametric magnetic resonance imaging (mpMRI) has shown potential as a non-invasive tool for evaluating renal allografts. This study aimed to evaluate whether mpMRI could serve biomarker predicting early allograft dysfunction. A total of 31 patients (44.4±10.9 years, 6 females) who underwent 1 month after kidney transplantation were included in the study. MpMRI parameters, including apparent diffusion coefficient (ADC), blood flow (RBF), and T1-rho (T1ρ), measured all patients. The...
An engineered old yellow enzyme lactone dehydrogenase (OYE1LD), which can reversibly catalyze the formation of C=C bonds and facilitate conversion lactones ketones into their α, β-unsaturated counterparts...
Abstract Background To investigate whether MRI findings, including texture analysis, can differentiate KRAS mutation status in rectal cancer. Methods Totally, 158 patients with pathologically proved cancers and preoperative pelvic examinations were enrolled. Patients stratified into two groups: wild-type group (KRAS wt group) mt according to genomic DNA extraction analysis. findings of (including features) relevant clinical characteristics statistically evaluated identify the differences...
In order to explore the microstructure of bilateral cingulum bundles associated with side and handedness, fractional anisotropy was extracted from diffusion tensor imaging. Distinguished conventional region interest-based method, a fiber-based analysis method called scale-invariant parameterization employed ascertain along bundle in 31 normal right-handers 14 left-handers. The statistical results showed remarkable left-greater-than-right asymmetry pattern most segments except posterior...