A5080648819- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Cardiac and Coronary Surgery Techniques
- Infective Endocarditis Diagnosis and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Aortic aneurysm repair treatments
- Mechanical Circulatory Support Devices
- Coronary Interventions and Diagnostics
- Electrospun Nanofibers in Biomedical Applications
- Surgical site infection prevention
- Tissue Engineering and Regenerative Medicine
- Cardiac Imaging and Diagnostics
- Congenital Heart Disease Studies
- Acute Myocardial Infarction Research
- Mesenchymal stem cell research
- Venous Thromboembolism Diagnosis and Management
- Cardiac Health and Mental Health
- Blood transfusion and management
- Cardiac Ischemia and Reperfusion
- Atrial Fibrillation Management and Outcomes
- Orthopedic Infections and Treatments
- Infectious Aortic and Vascular Conditions
- Cardiac tumors and thrombi
- Trauma Management and Diagnosis
University of Basel
2016-2025
University Hospital of Basel
2015-2024
Hirslanden Klinik Aarau
2024
Hospital Base
2022-2023
St. Claraspital
2018
John Wiley & Sons (United States)
2018
Hudson Institute
2018
Engineering Associates (United States)
2018
Paracelsus Medical University
2005-2013
Chest Diseases Hospital
2012
Importance Preoperative skin antisepsis is an established procedure to prevent surgical site infections (SSIs). The choice of antiseptic agent, povidone iodine or chlorhexidine gluconate, remains debated. Objective To determine whether in alcohol noninferior gluconate SSIs after cardiac abdominal surgery. Design, Setting, and Participants Multicenter, cluster-randomized, investigator-masked, crossover, noninferiority trial; 4403 patients undergoing surgery 3 tertiary care hospitals...
Assessment of postoperative quality life in patients over 80 years after cardiac surgery including coronary artery bypass grafting (CABG), aortic valve replacement (AVR) and combined procedures.Quality n=136 at operation (82.3+/-2.1 years), undergoing isolated CABG 61 (45%), AVR 34 (25%) a combination 41 (30%) between January 1999 December 2003 was reviewed. Preoperatively 66.2% presented NYHA-class III/IV or CCS-class III/IV. Mean ejection fraction (EF) 59.5%+/-14.0 (range 25-90%). Quality...
BackgroundMinimal extracorporeal circulation (MECC) is a promising perfusion technology, taking the advantage of an ECC while having significantly reduced priming volume. We analyzed actual possible benefits using MECC in patients undergoing CABG procedures and compared results with conventional (CECC).MethodsOne thousand fifty-three consecutive underwent surgery technique. Subgroup analyses focused on perioperative myocardial markers (cardiac troponin I [cTnI]), incidence atrial...
The ATS 3f Enable® Bioprosthesis is a self-expanding valve with tubular design that allows for decreased leaflet stress and preservation of aortic sinuses. We report the midterm results prospective, multicenter clinical study evaluating safety efficacy this stented bioprosthesis in patients undergoing isolated replacement or without concomitant procedures.A total 140 (mean age: 76 ± 6 years; 63% New York Heart Association (NYHA) stage III-IV) received Enable(®) 10 European centers between...
The purpose of this study was to evaluate prevalence, progression, treatment, and outcome silent coronary artery disease (CAD) in asymptomatic patients with diabetes (DM) at high risk. Despite the close association CAD, general CAD screening DM is discouraged even though data risk are lacking. Prospective multicenter study—with a pilot randomized treatment substudy. comprised 400 (type 2) without history or symptoms They underwent clinical evaluation myocardial perfusion single-photon...
Surgical revascularization is the gold standard in most cases of complex coronary artery disease. For bypass grafting, autologous grafts are state-of-the-art due to their long-term patency. A non-negligible amount patients lack suitable material as a result concomitant diseases or previous interventions. As promising alternative, tissue-engineered vascular made biomaterials such bacterial cellulose (BC) gaining more and attention. However, production small-diameter (inner diameter < 6 mm)...
Background— Since 1994 patients with acute aortic dissection type A (AADA) are followed-up in our outpatient clinic. Early diagnosis of secondary dilatation the diseased aorta is crucial to reduce late mortality these patients. Aim present study asses impact a large volume false lumen downstream on dilatation. Methods and Results— 134 264 who underwent surgery for AADA (between January June 2003) at clinic since 1994. 84 (62.7%) fulfilled inclusion criteria. Areas true lumens were analyzed...
OBJECTIVE To assess the clinical implementation and report preliminary results of a novel technique called Ozaki procedure for stentless aortic valve replacement through reconstruction leaflets from autologous pericardium. METHOD Between September 2015 May 2017 30 patients (20 males, mean ± standard deviation age 66.83 10.55 years) suffering stenosis (AS, n = 7), regurgitation (AR, 12), or combination both (AS/AR, 11) were assigned an procedure. The glutaraldehyde-treated pericardium was...
Background: Aim of this study was to evaluate the outcomes endocarditis patients undergoing valve surgery with Cytosorb® hemoadsorption (HA) device during cardiopulmonary bypass. Methods: From 2009 until 2019, 241 had undergone due at Department Cardiac Surgery, University Hospital Basel. We compared who received HA (n = 41) versus without 200), after applying inverse probability treatment weighting. Results: In-hospital mortality, major adverse cardiac and cerebrovascular events...
Prompt diagnosis of subsequent dilatation the dissected aorta is crucial to reduce late mortality in these patients. This study focuses on risk factors for after type A aortic dissection (AADA) affecting a normal-sized or slightly dilated aorta.Overall 531 CT scans were analysed. Patients included if at least 3 available operative repair. 64 patients (59.8%) out 107 full-field inclusion criteria. Volumetric analyses performed. divided groups: group 26 (40.6%) without progression diameter, 2,...
Wire closure still remains the preferred technique despite reasonable disadvantages. Associated complications, such as infection and sternal instability, cause time- cost-consuming therapies. We present a new tool for with its first clinical experience results. The ZipFixTM System is based on cable-tie principle. It primarily consists of biocompatible Poly-Ether-Ether-Ketone implants predominantly used peristernally through intercostal space. system provides large implant-to-bone contact...
Conventional tissue engineering strategies often rely on the use of a single progenitor cell source to engineer in vitro biological models; however, multi-cellular environments can better resemble complexity native tissues. Previous described co-culture models used skeletal myoblasts, as parenchymal source, and mesenchymal or endothelial cells, stromal component. Here, we propose instead adipose tissue-derived vascular fraction which include both stroma. Percentage serum supplementation is...
This study compares the influence of two different annuloplasty attachment suture applications, namely use an automated fastener versus manually tied knots using a traditional knot pusher, on total operation time, cardiopulmonary-bypass time and cross-clamp short-term outcome. Sixty patients underwent isolated minimally invasive mitral valve repair in Carpentier Type-II disease with implantation ring combination correction prolapsing leaflet artificial chords. The first 30 after...
Abstract Background Preliminary studies that analyzed surrogate markers have suggested operating room (OR) door openings may be a risk factor for surgical site infection (SSI). We therefore aimed to estimate the effect of OR on SSI in patients undergoing cardiac surgery. Methods This prospective, observational study involved consecutive surgery 2 prespecified ORs equipped with automatic door-counting devices from June 2016 October 2017. Occurrence an within 30 days after was our primary...