Additive manufacturing (AM) is rapidly gaining acceptance in the healthcare sector. Three-dimensional (3D) virtual surgical planning, fabrication of anatomical models, and patient-specific implants (PSI) are well-established processes fields. Polyetheretherketone (PEEK) has been used, mainly reconstructive surgeries as a reliable alternative to other alloplastic materials for PSI. Recently, it become possible fabricate PEEK PSI with Fused Filament Fabrication (FFF) technology. 3D printing...

With the rapid progression of additive manufacturing and emergence new 3D printing technologies, accuracy assessment is mostly being performed on isosymmetric test bodies. However, anatomic models can vary. The dimensional root mean square values in terms trueness precision 50 mandible replicas, printed with five common were evaluated. highest was found for selective laser sintering printer (0.11 ± 0.016 mm), followed by a binder jetting (0.14 0.02 fused filament fabrication (0.16 0.009 mm)....

Polyetheretherketone (PEEK) is a prime candidate to replace metallic implants and prostheses in orthopedic, spine cranio-maxillofacial surgeries. Fused-filament fabrication (FFF) an economical efficient three-dimensional (3D) printing method fabricate PEEK implants. However, studies pertaining the bioactivity of FFF 3D printed are still lacking. In this study, samples were fabricated modified with polishing grit-blasting (three alumina sizes: 50, 120, 250 µm) achieve varying levels surface...

Computer-assisted surgery with three-dimensional (3D) printed surgical guides provides more accurate results than free-hand surgery. Steam sterilization could be one of the factors that affect dimensions guide resin materials, leading to inaccuracies during surgeries. The purpose this study was evaluate effects steam on dimensional accuracy indication-specific hollow cube test bodies, manufactured in-house using Class IIa biocompatible materials (proprietary and third-party). To pre-...

Recent advancements in medical imaging, virtual surgical planning (VSP), and three-dimensional (3D) printing have potentially changed how today’s craniomaxillofacial surgeons use patient information for customized treatments. Over the years, polyetheretherketone (PEEK) has emerged as biomaterial of choice to reconstruct craniofacial defects. With additive manufacturing (AM) systems, prospects point-of-care (POC) 3D PEEK patient-specific implants (PSIs) emerged. Consequently, investigating...

The most common three-dimensional (3D) printing method is material extrusion, where a pre-made filament deposited layer-by-layer. In recent years, low-cost polycaprolactone (PCL) has increasingly been used in 3D printing, exhibiting sufficiently high quality for consideration cranio-maxillofacial reconstructions. To increase osteoconductivity, prefabricated filaments bone repair based on PCL can be supplemented with hydroxyapatite (HA). However, few reports PCL/HA composite extrusion...

Polyetheretherketone (PEEK), a biomaterial with appropriate bone-like mechanical properties and excellent biocompatibility, is widely applied in cranio-maxillofacial dental applications. However, the lack of antibacterial effect an essential drawback PEEK material might lead to infection osseointegration issues. This study aims apply natural agent, totarol coating onto 3D printed surface find optimized concentration balanced cytocompatibility, osteogenesis, capability.

Abstract Background Bioresorbable patient-specific additive-manufactured bone grafts, meshes, and plates are emerging as a promising alternative that can overcome the challenges associated with conventional off-the-shelf implants. The fabrication of implants (PSIs) directly at point-of-care (POC), such hospitals, clinics, surgical centers, allows for more flexible, faster, efficient processes, reducing need outsourcing to external manufacturers. We want emphasize potential advantages...

Additive manufacturing (AM) of patient-specific implants (PSIs) is gradually moving towards in-house or point-of-care (POC) manufacturing. Polyetheretherketone (PEEK) has been used in cranioplasty cases as a reliable alternative to other alloplastic materials. As only few fused filament fabrication (FFF) printers are suitable for manufacturing, the quality characteristics fabricated by FFF technology still under investigated. This paper aimed investigate PEEK PSIs craniofacial...

Reconstruction of cranial defects is an arduous task for craniomaxillofacial surgeons. Additive manufacturing (AM) or three-dimensional (3D) printing titanium patient-specific implants (PSIs) made its way into cranioplasty, improving the clinical outcomes in complex surgical procedures. There has been a significant interest within medical community redesigning based on natural analogies. This paper proposes workflow to create biomimetic prosthesis with interconnected strut macrostructure...

Recently, three-dimensional (3D) printing has become increasingly popular in the medical sector for production of anatomical biomodels, surgical guides, and prosthetics. With availability low-cost desktop 3D printers affordable materials, in-house or point-of-care manufacturing biomodels Class II devices gained considerable attention personalized medicine. Another projected development treatment is patient-specific implants (PSIs) partial total bone replacements made medical-grade material...

The objective of this study was to determine the effect two plasma surface treatments on biologic responses PEEK medical implants manufactured by fused filament fabrication (FFF) 3D printing technology.This created standard samples using an FFF printer. After fabrication, half were polished simulate a smooth surface. Then, argon (Ar) or oxygen (O2) used modify bioactivity printed and samples. Scanning electron microscopy (SEM) profilometer microstructure roughness sample surfaces....

Additive manufacturing (AM) of polyetheretherketone (PEEK) biomaterials using the material-extrusion (MEX) method has been studied for years. Because challenging process, precisely controlling printing parameters is crucial. This study aimed to investigate effects such as orientation and position on mechanical properties. Thus, 34 samples were printed PEEK filament MEX process. Samples divided into two main groups (A,B) according their orientations (A: 1–3) positions build plate (B: 4–8)....

The use of patient-specific implants (PSIs) in craniofacial surgery is often limited due to a lack expertise and/or production costs. Therefore, simple and cost-efficient template-based fabrication workflow has been developed overcome these disadvantages. aim this study assess the accuracy PSIs made from their original templates. For representative cranial defect (CRD) temporo-orbital (TOD), ten were polymethylmethacrylate (PMMA) using computer-aided design (CAD) three-dimensional (3D)...

To develop a novel 3D-printer-assisted method to fabricate patient-specific implants for cranioplasty and demonstrate its feasibility use in 16 consecutive cases. We report on patients who have undergone surgery an extensive skull defect after decompressive which the bone flap was not available. present workflow implant production using molding technique. Preoperative, intraoperative, postoperative data were analyzed/evaluated. Eleven out of our (68.7%) presented with hemispheric defects....

This study evaluates the accuracy of drill guides fabricated in medical-grade, biocompatible materials for static, computer-aided implant surgery (sCAIS). The virtually planned ten completed patient cases were printed (n = 40) using professional (Material Jetting (MJ)) and consumer-level three-dimensional (3D) printing technologies, namely, Stereolithography (SLA), Fused Filament Fabrication (FFF), Digital Light Processing (DLP). After post-processing, digitized an optical scanner....

Polylactic acid (PLA) has been widely used as filaments for material extrusion additive manufacturing (AM) to develop patient-specific scaffolds in bone tissue engineering. Hydroxyapatite (HA), a major component of natural bone, extensively recognized an osteoconductive biomolecule. Here, inspired by the mussel-adhesive phenomenon, this study, polydopamine (PDA) coating was applied surface 3D printed PLA (PLA@PDA), acting versatile adhesive platform immobilizing HA nanoparticles (nHA)....

Additive manufacturing (AM) is an increasingly important technology for fabricating complex and customized structures using a range of advanced materials now playing critical role in the field bone tissue engineering (BTE). Two-dimensional nanomaterials (2D NMs) have demonstrated their significance biomedical science. The convergence 2D NMs to 3D printing (3DP) create desired scaffolds has become alternative approach breakthrough bottlenecks remaining challenges BTE, which can potentially...

Cleft lip and palate are one of the most common congenital craniofacial malformations. As an initial treatment, presurgical orthopedics is considered standard treatment at many cleft centers. Digital impressions becoming feasible in care. Computer-aided design (CAD) three-dimensional (3D) printing manufacturing standards dentistry. The assimilation these technologies has potential to alter traditional workflow for fabrication customized orthopedic plates. We present a digital comprising...

3D printed biomaterials have been extensively investigated and developed in the field of bone regeneration related to clinical issues. However, specific applications different dental areas seldom reported. In this study, we aimed successfully fabricated poly (lactic-co-glycolic acid)/β-tricalcium phosphate (3D-PLGA/TCP) β-tricalcium (3D-TCP) scaffolds using two relatively distinct printing (3DP) technologies. Conjunctively, compared mechanical biological responses on human pulp stem cells...

Abstract Various cranioplasty techniques exist for the reconstruction of cranial bone defects. Patient-specific implants can be produced in-house using a recently developed 3D printer-assisted technique. However, resulting cosmetic outcomes from patient’s perspective are underreported. With our case series, we aim to present clinical outcome, morbidity rate, patient-reported results, and cost-effectiveness patient-specific3D This is consecutive retrospective series adult patients undergoing...