- Tuberous Sclerosis Complex Research
- Kruppel-like factors research
- Cancer-related gene regulation
- MicroRNA in disease regulation
- Chromatin Remodeling and Cancer
- Histiocytic Disorders and Treatments
- RNA modifications and cancer
- Cancer-related molecular mechanisms research
Cancer Research UK Manchester Institute
2025
University of Manchester
2025
Indian Institute of Science Bangalore
2020-2021
Aberrant activation of the PI3K/AKT/mTOR pathway is attributed to pathogenesis oral squamous cell carcinoma (OSCC). In recent years, increasing evidence suggests involvement microRNAs (miRNAs) in carcinogenesis by acting as tumor suppressors or oncogenes. TSC1, a component above pathway, regulates several cellular functions such proliferation, apoptosis, migration and invasion. Downregulation TSC1 reported well other cancers associated with an unfavourable clinical outcome patients. Here we...
Abstract Aberrant activation of the PI3K/AKT/mTOR pathway is attributed to pathogenesis oral squamous cell carcinoma (OSCC). In recent years, increasing evidence suggests involvement microRNAs (miRNAs) in carcinogenesis by acting as tumor suppressors or oncogenes. TSC1, a component above pathway, regulates several cellular functions such proliferation, apoptosis, migration and invasion. Downregulation TSC1 reported well other cancers associated with an unfavourable clinical outcome patients....