A5045360316- Nanoparticle-Based Drug Delivery
- Natural product bioactivities and synthesis
- RNA Interference and Gene Delivery
- Photodynamic Therapy Research Studies
- Flavonoids in Medical Research
University of Wrocław
2022-2023
Pancreatic cancer (PC) is one of the deadliest cancers so there an urgent need to develop new drugs and therapies treat it. Liposome-based formulations naturally-derived bioactive compounds are promising anticancer candidates due their potential for passive accumulation in tumor tissues, protection against payload degradation, prevention non-specific toxicity. We chose flavonoid baicalein (BAI) its effect pancreatic ductal adenocarcinoma (PDAC) encapsulated it into a liposomal bilayer using...
Despite many attempts, trials, and treatment procedures, pancreatic ductal adenocarcinoma (PDAC) still ranks among the most deadly treatment-resistant types of cancer. Hence, there is an urgent need to develop new molecules, drugs, therapeutic methods against PDAC. Naturally derived compounds, such as pentacyclic terpenoids, have gained attention because their high cytotoxic activity toward cancer cells. Ursolic acid (UA), example, possesses a wide anticancer spectrum can potentially be good...