Irini Lazou Ahrén

ORCID: 0000-0003-3410-7976
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About
Contact & Profiles
Research Areas
  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Bacterial Infections and Vaccines
  • Infant Health and Development
  • Pneumonia and Respiratory Infections
  • Diet and metabolism studies
  • Pediatric health and respiratory diseases
  • Microbial Metabolites in Food Biotechnology
  • Peptidase Inhibition and Analysis
  • Inhalation and Respiratory Drug Delivery
  • Wound Healing and Treatments
  • Pharmacological Effects of Natural Compounds
  • Biochemical effects in animals
  • Phytochemicals and Antioxidant Activities
  • Synthesis and Biological Evaluation
  • Phytoestrogen effects and research
  • Bone Metabolism and Diseases
  • Inflammatory Bowel Disease
  • Immune Response and Inflammation
  • Tea Polyphenols and Effects
  • Natural Antidiabetic Agents Studies
  • Gastrointestinal motility and disorders
  • Effects of Radiation Exposure
  • Helicobacter pylori-related gastroenterology studies
  • Clostridium difficile and Clostridium perfringens research

Probi
2013-2023

Ideon Science Park
2016-2022

Lund University
2001-2003

Malmö University
2001

Czech Academy of Sciences, Institute of Microbiology
2001

Probiotics are live microorganisms which have beneficial effects on the host when ingested in adequate amounts. Probiotic bacteria may stimulate immune effector functions a strain-specific manner. In this blind placebo-controlled trial, we investigated system following daily intake of six different strains lactobacilli or Gram-negative bacterium Pseudomonas lundensis for 2 5 weeks. Blood lymphocyte subsets were quantified by fluorescence activated cell sorter and expression activation memory...

10.1111/cei.12055 article EN Clinical & Experimental Immunology 2012-12-26

Objective. To clarify the effect of Lactobacillus plantarum 299v on salivary cortisol and IgA levels in young adults under examination stress. Design. Forty-one students with an upcoming academic exam were included a randomized double-blind, placebo-controlled study. The probiotic bacteria or placebo product was administered capsules once day during 14 days. Saliva collected perceived stress test filled out at each sampling occasion. for analysis by Electrochemiluminescence Immunoassay...

10.1155/2016/8469018 article EN cc-by International Journal of Microbiology 2016-01-01

Previous reports showed that nontypeable Haemophilus influenzae (NTHi) reside in macrophage-like cells human adenoid tissue. This study investigated the ability of nonopsonized NTHi and encapsulated H. type b (Hib) to enter monocytic epithelial cells. The number intracellular bacteria was determined by a viability assay flow cytometry. To characterize mechanisms responsible for internalization NTHi, different inhibitors surface molecules, receptor turnover, cytoskeleton were used. Hib found...

10.1086/322016 article EN The Journal of Infectious Diseases 2001-07-15

Eosinophils are a characteristic component of the inflammatory response seen in several diseases, including allergic asthma and chronic obstructive pulmonary disease. After activation, eosinophil-derived products may exert proinflammatory effects cause considerable tissue damage. In present study, we investigated innate interactions between respiratory tract pathogen nontypeable Haemophilus influenzae (NTHi) human eosinophils. Bacterial binding to eosinophils was dependent on...

10.1165/rcmb.2002-0138oc article EN American Journal of Respiratory Cell and Molecular Biology 2003-04-15

Prebiotics, probiotics, or synbiotics can be used as means to regulate the microbiota exert preventative beneficial effects host. However, not much is known about effect of gut on hypertension which a major risk factor cardiovascular disease and also symptom metabolic syndrome. The<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"...

10.1155/2013/809128 article EN Evidence-based Complementary and Alternative Medicine 2013-01-01

Viral infections of the upper airways are most common cause for absence from work or school, and there is evidence probiotic efficacy in reducing incidence severity these infections.

10.1093/jn/nxaa353 article EN cc-by Journal of Nutrition 2020-10-16

Abstract Background The combination of Lactobacillus plantarum HEAL9 and paracasei 8700:2 (commercially available as Probi Defendum ® ) has previously been reported to reduce the incidence, duration severity naturally acquired common colds in adults. aim present study was evaluate impact on aspects cold healthy children 1–6 years age attending day care. Methods A total 131 children, out planned 320, were recruited into during 1 season randomised consume once daily either 10 9 CFU (colony...

10.1007/s00394-019-02137-8 article EN cc-by European Journal of Nutrition 2019-11-16

Consumption of polyphenol-rich fruits and vegetables may improve postprandial glucose insulin levels hence promote well-being. Previously it has been observed that consumption bilberry decreases the demand. The intention with present study was to compare impact different supplements various polyphenol profiles, on responses in healthy young adults. In a randomized, controlled, crossover glycemic were eleven adults after intake five beverages containing (European blueberry), blackcurrant,...

10.1186/s12937-018-0335-0 article EN cc-by Nutrition Journal 2018-02-27

Nontypeable Haemophilus influenzae (NTHi) is a common cause of respiratory tract infections. This study investigated the ability NTHi to bind lipopolysaccharide-binding protein (LBP) derived from epithelial cells and subsequent stimulation transfected expressing membrane-bound CD14 toll-like receptor 2 (TLR2) or TLR4. In absence LBP, at high concentrations (100 bacteria/epithelial cell) were required induce signals through TLR2 Flow cytometry showed that in stationary phase bound more LBP...

10.1086/323398 article EN The Journal of Infectious Diseases 2001-10-01

Non-typeable Haemophilus influenzae, which is a cause of disease in the upper and lower respiratory tract, can survive intracellularly human epithelial cells macrophages. We studied vitro activity five antibiotics against intracellular non-typeable H. influenzae type II alveolar cells. The eukaryotic were loaded with bacteria, extracellular bacteria killed by gentamicin. After washed, added at concentrations 0.12-64 mg/L for 18 h before numbers viable determined. Of tested, ciprofloxacin...

10.1093/jac/dkf221 article EN Journal of Antimicrobial Chemotherapy 2002-11-18

Abstract Obesity is a risk factor for cardio-metabolic and neurological disease. The contribution of gut microbiota to derangements the gut-brain axis in context obesity has been acknowledged, particularly through physiology modulation by short-chain fatty acids (SCFAs). Thus, probiotic interventions administration SCFAs have employed with purpose alleviating symptoms both metabolic We investigated effects four butyrate-producing bacteria from Lachnospiraceae family on development syndrome...

10.1163/18762891-bja00040 article EN Beneficial Microbes 2017-01-01

Abstract Obesity is a risk factor for cardio-metabolic and neurological disease. The contribution of gut microbiota to derangements the gut-brain axis in context obesity has been acknowledged, particularly through physiology modulation by short-chain fatty acids (SCFAs). Thus, probiotic interventions administration SCFAs have employed with purpose alleviating symptoms both metabolic We tested effects four butyrate-producing bacteria from Lachnospiraceae family on development syndrome...

10.1101/2023.11.02.564919 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-11-04

Faecal samples have often been used to characterise the gut microbiota in health and disease. There is significant debate whether faecal bacterial communities accurately reflect mucosa associated populations, which are considered critical aetiopathogenesis of several gastrointestinal diseases. We simultaneously assessed mucosal from healthy volunteers unravel degree concordance between two profiles. Paired fresh rectal biopsies were obtained ten processed under stringent anaerobic...

10.1099/acmi.ac2020.po0261 article EN cc-by-nc Access Microbiology 2020-07-01
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