Paula Mustonen

ORCID: 0000-0003-3413-3410
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About
Contact & Profiles
Research Areas
  • Maternal Mental Health During Pregnancy and Postpartum
  • Stress Responses and Cortisol
  • Folate and B Vitamins Research
  • Dermatology and Skin Diseases
  • Gut microbiota and health
  • Child and Adolescent Psychosocial and Emotional Development
  • Infant Development and Preterm Care
  • Tryptophan and brain disorders
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Infant Health and Development
  • Orthopedic Surgery and Rehabilitation
  • Vitamin C and Antioxidants Research
  • Neuroendocrine regulation and behavior
  • Psychosomatic Disorders and Their Treatments
  • Advanced Neuroimaging Techniques and Applications
  • Dental Education, Practice, Research
  • Dental Anxiety and Anesthesia Techniques
  • Pediatric Pain Management Techniques
  • Gestational Diabetes Research and Management
  • Fluoride Effects and Removal
  • Birth, Development, and Health
  • Orthodontics and Dentofacial Orthopedics
  • Fibromyalgia and Chronic Fatigue Syndrome Research

University of Turku
2017-2024

Turku University Hospital
2017-2024

Maternal prenatal stress associates with infant developmental outcomes, but the mechanisms underlying this association are not fully understood. Alterations in composition and function of intestinal microbiota may mediate some observed health effects, a viewpoint that is supported by animal studies along small human study showing exposure to modifies offspring's microbiota. In current study, we aim investigate associations between maternal psychological distress (PPD) hair cortisol...

10.1016/j.psyneuen.2020.104754 article EN cc-by-nc-nd Psychoneuroendocrinology 2020-06-05

Maternal prenatal cortisol levels have been inconsistently associated with self-reports of psychological distress (PD). Previous research has linked hair concentration (HCC) evaluating cumulatively the previous months cross-sectional PD measures that usually cover past week(s), which may lead to misleading conclusions on their relations. We aimed investigate how maternal HCC relates cumulative across pregnancy.Subjects (N = 595) were drawn from FinnBrain Birth Cohort Study. was measured...

10.1016/j.psyneuen.2019.104383 article EN cc-by-nc-nd Psychoneuroendocrinology 2019-07-30

Maternal prenatal distress can participate in the programming of offspring development, which exposure to altered maternal long-term cortisol levels as measured by hair concentrations (HCC) may contribute. Yet, studies investigating whether and how HCC associates with problems child socioemotional development are scarce. Furthermore, questions remain regarding timing potential sex-specificity fetal there interactions distress, such depressive symptoms. The subjects were drawn from those...

10.1016/j.psyneuen.2023.106955 article EN cc-by Psychoneuroendocrinology 2024-01-04

Introduction: Alexithymia, a personality construct characterized by difficulties in identifying and expressing emotions, an externally oriented thinking style, has been associated with number of stress-related disorders, physiological markers stress. We examined the relationships alexithymia hair cortisol concentrations (HCC), measure long-term levels, pregnant women. Methods: Participants were 130 women from FinnBrain birth cohort study. Alexithymia was measured Toronto Scale (TAS-20)....

10.3389/fpsyt.2020.00421 article EN cc-by Frontiers in Psychiatry 2020-05-13

Animal research suggests that the gut microbiota and HPA axis communicate in a bidirectional manner. However, human data, especially on early childhood, remain limited. In this exploratory design, we investigated connections between long-term functioning, measured as cortisol, cortisone or dehydroepiandrosterone concentrations their ratios from hair segments of three centimeters, profiles, (measured diversity bacterial composition by 16 S rRNA sequencing) healthy 2.5-year-old toddlers (n =...

10.1016/j.psyneuen.2023.106309 article EN cc-by-nc-nd Psychoneuroendocrinology 2023-05-25

Maternal prenatal depressive symptoms are linked to neurodevelopmental impairments in offspring. cortisol levels hypothesized moderate this association, but its relationship with is inconsistent. This study examined how maternal and predict infant brain development, focusing on neonatal corpus callosum (CC) integrity. Using data from the FinnBrain Birth Cohort Study, we analyzed 37 mother-infant dyads. MRI were collected 2 5 weeks old infants, DTI imaging estimated fractional anisotropy (FA)...

10.1101/2024.09.06.610927 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-09-12

Dental anxiety (DA) and hair cortisol concentrations (HCC) are associated with psychological symptoms vary during pregnancy. We aimed to examine the association between HCC DA at two points of Participants were pregnant mothers (n = 533) drawn from FinnBrain Birth Cohort Study donating a sample gestational week (gwk) 24 442) and/or delivery 176) completed questionnaires on DA. Two groups, HCC1 HCC2, treated as separate in analyses, formed according donation time i.e., gwk24 delivery. 85...

10.3390/dj9040042 article EN cc-by Dentistry Journal 2021-04-11
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