A5018533788- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Nanoparticles: synthesis and applications
- Quantum Dots Synthesis And Properties
- Metabolism and Genetic Disorders
- X-ray Diffraction in Crystallography
- Diet and metabolism studies
- Crystallization and Solubility Studies
- Antifungal resistance and susceptibility
- Drug-Induced Hepatotoxicity and Protection
- Pharmacogenetics and Drug Metabolism
- Hepatitis C virus research
- Alcohol Consumption and Health Effects
- Crystallography and molecular interactions
- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Selenium in Biological Systems
- Diet, Metabolism, and Disease
- Platelet Disorders and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Liver Disease and Transplantation
- Metabolomics and Mass Spectrometry Studies
- Cholinesterase and Neurodegenerative Diseases
- Curcumin's Biomedical Applications
- thermodynamics and calorimetric analyses
Universidad Autónoma del Estado de Morelos
2014-2024
Universidad Autónoma del Estado de México
2009-2020
Center for Research and Advanced Studies of the National Polytechnic Institute
2017-2020
Champlain Valley Union High School
2020
Universidad Del Valle De Cuernavaca
2013
University of New Mexico
2011
Universidad Panamericana
1999
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
1995-1998
Despite steady progress in therapeutics of liver disease, portal systemic encephalopathy remains to be a great challenge for clinicians because the heterogeneity neuropsychiatric symptoms, multiple risk factors and complexity on achieving sustained response. We aimed evaluate efficacy L-Ornithin, L-Aspartate versus lactulose Mexican patients with hyperammonemic hepatic encephalopathy. A total 20 were randomly allocated receive either (n = 10) or L-ornithine – L-aspartate 2 weeks. At...
Amphotericin B is the most potent antimycotic known to date. However due its large collateral toxicity, use, although long standing, had been limited. Many attempts have made produce derivatives with reduced damage. The molecular mechanism of polyene has also closely studied for this purpose and understanding it would contribute development safe derivatives. Our study examined action, including chemical synthesis, electrophysiology, pharmacology, toxicology dynamics. results were used...
Semiconductor Quantum dots (QDs) have become quite popular thanks to their properties and wide use in biological biomedical studies. However, these same entail new challenges understanding, predicting, managing potential adverse health effects following exposure. Cadmium selenium, which are the major components of majority quantum dots, known be acutely chronically toxic cells organisms. Protecting core nanoparticles can, some degree, control toxicity related cadmium selenium leakage.This...
The safe use in biomedicine of semiconductor nanoparticles, also known as quantum dots (QDs), requires a detailed understanding the biocompatibility and toxicity QDs human beings. biological characteristics physicochemical properties entail new challenges regarding management potential adverse health effects following exposure. At certain concentrations, synthesis nanoparticles CdS using dextrin capping agent, at concentration, to reduce their improves biocompatibility. This study...
Cocrystallization experiments of three representative aromatic boronic acids, namely phenylboronic acid (PBA), 1,4-benzenediboronic (BDBA) and 4-iodophenylboronic (IPBA), with a series essential amino nicotinamide (NA) isonicotinamide (INA) gave total nine molecular complexes the compositions: PBA–PRO (1 : 1), PBA–PRO–H2O 1 α-BDBA–PRO 2), β-BDBA–PRO α-IPBA–PRO β-IPBA–PRO BDBA–INA IPBA–INA 1) IPBA–NA where PRO = L-proline. Of these, α-BDBA–PRO/β-BDBA–PRO α-IPBA–PRO/β-IPBA–PRO were true...
Abstract Among the eight Calophyllum species found on American continent, brasiliense is most widely distributed. Chemical analysis of this has shown presence xanthones with cancer chemopreventive properties and antifungal activity. Recently, three new coumarins antineoplastic have been found. In study, we evaluated biological effects antiproliferative activity isolated from C. survival, cell cycle apoptosis cells in-vitro their antitumour in mice. The cytological study showed that reduce...
Chagas Disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, affecting 6–8 million people, mainly in Latin America. The medical treatment based on two compounds, benznidazole and nifurtimox, with limited effectiveness that produce severe side effects; consequently, there an urgent need to develop new, safe, effective drugs. Amphotericin B most potent antimycotic known date. A21 derivative of this compound property binding ergosterol present cell...
To evaluate the effect of genistein on fibrosis and matrix degradation caused by experimentally induced in rats.Hepatic was brought about chronic administration carbon tetrachloride to rats. liver function, total collagen content proteolytic activity were quantified. Urokinase-type plasminogen activator (uPA) expression during experimental localized immunohistochemistry. Histopathological changes evaluated using light electron microscopy.Animals with treated showed an important reduction...
Fibrosis accompanies most chronic liver disorders and is a major factor contributing to hepatic failure. Therefore, the need for an effective treatment with aim of modifying clinical course this disease evident. The work determine whether genistein, which has been shown modulate physiology pathophysiology liver, able decrease experimental fibrosis cholestasis. In male Wistar rats, common bile duct was ligated. Administration genistein (5 microg rat-1, day-1, p.o.) began four weeks after...
Coriander has been used as a spice and medicinal plant for centuries. Several studies have described its biological properties some reports indicated pharmacological actions in human pathology. However, data on toxicity metabolism are limited or null, no research conducted with mammalian cells. The purpose of this study was to evaluate the mutagenicity safety Coriandrum sativum extract. mutagenic effects C. extract were evaluated by Ames test. Mutagenicity present when high concentrations...
Thrombocytopenia is a common hematologic disorder observed in patients with chronic hepatitis C virus (HCV) infection. Combined peginterferon (PEG-INF) and ribavirin treatment may exacerbate thrombocytopenia HCV.The aim of this pilot clinical trial was to assess the efficacy, tolerability safety Danazol associated PEG-INF HCV.We included whose platelets were < 90,000/mm³ who undergoing antiviral treatment. (300-600 mg/day) administered during until end therapy [7.6 months (2 11 months)]. The...
Tibia fractures are common in small animal practice. Over the past decade, improvements to internal fracture fixation have been developed. TGF-β1 has shown be crucial development, induction and repair of bone. In present study, we investigate effect local application a graft demineralized bone matrix (DBM) along with model open osteotomy induced experimentally dogs. was brought about by using an young male Fracture evaluated histological biochemical analysis. Collagen content, proteolytic...
Introduction. Immunomodulatory drugs have been reported to anti-inflammatory and anti-fibrotic properties. Thymic Humoral Factor (THF), a peptide produced in the thymus, causes potent immunomodulatory effect on different components of immune system. Objective. To evaluate THF stages liver damage fibrosis induced rats through administration porcine serum (PS). Material methods. PS-induced models serve as primarily immunological mechanism development fibrosis. Results. The intraperitoneal with...
Probiotics have been used in humans for almost a century and are widely recommended because they play an important role gastrointestinal physiological pathophysiological processes. The aim of this study was to evaluate the effi- cacy safety probiotic mixture healthy volunteers with evacuation disorders. We undertook prospective historical control. number evacuations, effort stool consistency 10 days before, during after treatment as primary outcome measures. Eligible par-ticipants comprised...