Juan Carlos López-Hernández

ORCID: 0000-0003-3419-5160
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Peripheral Neuropathies and Disorders
  • Long-Term Effects of COVID-19
  • Hereditary Neurological Disorders
  • Autoimmune Neurological Disorders and Treatments
  • Infectious Encephalopathies and Encephalitis
  • Muscle Physiology and Disorders
  • Neurogenetic and Muscular Disorders Research
  • Myasthenia Gravis and Thymoma
  • Neurology and Historical Studies
  • Peripheral Nerve Disorders
  • Nerve injury and regeneration
  • Parkinson's Disease and Spinal Disorders
  • Genetic Neurodegenerative Diseases
  • Inflammatory Myopathies and Dermatomyositis
  • SARS-CoV-2 and COVID-19 Research
  • Reproductive biology and impacts on aquatic species
  • Botulinum Toxin and Related Neurological Disorders
  • Antifungal resistance and susceptibility
  • Cancer Treatment and Pharmacology
  • Agroforestry and silvopastoral systems
  • Epilepsy research and treatment
  • Cardiomyopathy and Myosin Studies
  • Amyotrophic Lateral Sclerosis Research
  • Electroconvulsive Therapy Studies
  • Mitochondrial Function and Pathology

Instituto Nacional de Neurología y Neurocirugía
2018-2025

Hospital de Clínicas
2023-2024

Autonomous University of Chiapas
2022-2023

Asociación Mexicana de Psicología y Desarrollo Comunitario
2021-2023

CEA LIST
2023

Deleted Institution
2023

Hospital Civil de Guadalajara
2015-2021

Dean Martin Neuromuscular Clinic
2020-2021

Universidad Panamericana
2021

Neurology, Inc
2021

Introduction: Autoimmune encephalitis (AE) represents a severe neuropsychiatric disorder that requires early diagnosis. This study describes the frequency, clinical characteristics, and paraclinical findings in patients with possible autoimmune treated neurological emergency department, as well factors associated poor functional prognosis at discharge. Material Methods: was an observational ambispective cohort including diagnosed AE who were department 2022. Demographic, clinical,...

10.31083/rn36202 article EN cc-by Revista de Neurología 2025-03-05

During the COVID-19 pandemic, an increase in number of Guillain-Barre syndrome (GBS) cases has been reported.To describe clinical characteristics and prognosis patients with GBS before during pandemic.Prospective cohort divided two subgroups: (2018-2019) (2020-2021) pandemic. Clinical paraclinical characteristics, as well deaths, were recorded. A good was defined independent ambulation recovery at three months.Two-hundred one included (123 78 pandemic), out whom 69% males; age 45 ± 16 years,...

10.24875/gmm.m23000787 article EN cc-by-nc-nd Gaceta Médica de México 2023-09-06

Studies on environmental pollution in Mexican freshwater ecosystems by means of fish histopathology are extremely scarce.In that view, this research analyzed the gonad four teleost species from a hyper-eutrophicated fragmented urban lagoon, order to determine possible harmful effects water pollutants their reproductive fitness.Gonads were processed histological conventional techniques.The gonadal alterations detected both, clupeid Dorosoma petenense and cichlid Thorichthys meeki expose need...

10.20937/rica.2017.33.04.14 article EN cc-by-nc Revista Internacional de Contaminación Ambiental 2017-10-30

Introduction: Hyponatremia occurs in 21-48% of patients with Guillain-Barre syndrome (GBS).However, little is known about the clinical implications GBS.Materials and methods: In this observational, cross-sectional study, diagnosed GBS was conducted.Information used included: demographic variables, cerebrospinal fluid (CSF) results, nerve conduction studies.Patients sodium levels < 135 meq/L laboratory studies on admission before treatment were considered to have hyponatremia.We defined good...

10.24875/rmn.22000081 article EN cc-by-nc-nd DELETED 2023-05-15

Introduction: Twenty to 40% of Guillain Barré syndrome (GBS) patients will not be able walk independently despite effective treatment. Older carry additional risks for worse outcomes. Methods: A single center, ambispective cohort study was performed. Only subjects ≥18 years with a 3-month follow-up were included. Elderly considered as whole if ≥ 60 years. Demographics, CSF and nerve conduction studies compared. binomial logistic regression Kaplan-Meier analyses carried out estimate good...

10.1177/19418744211002676 article EN The Neurohospitalist 2021-03-22

Antecedentes: La hipovitaminosis D ha sido asociada con diversas enfermedades crónicas como infecciones, autoinmunes, enfermedad pulmonar obstructiva crónica, cáncer y asma.Objetivo: Determinar la prevalencia de insuficiencia deficiencia vitamina (VD) en adultos asma alérgica.Métodos: Estudio transversal el que se analizaron los datos 135 pacientes. concentración VD fue categorizada suficiente (≥ 30 ng/mL), insuficiente (21-29 ng/mL) deficiente (≤ 20 ng/mL). midió por quimioluminiscencia. Se...

10.29262/ram.v64i2.255 article ES cc-by-nc Deleted Journal 2017-06-29

To describe clinical characteristics and electrophysiological variants of GBS cases during the pandemic, we carried out a comparative analysis between SARS-CoV2 related non-SARS-CoV2 patients then compared to 2019 cases.We cross-sectional study diagnosed according Asbury Cornblath criteria. We collected information on paraclinical variables. defined SARS-CoV-2 case description Ellul et al. used Hadden criteria classify variants. performed groups.Fourty-two were with in 2020, men 64.2%, age...

10.33588/rn.7309.2021364 article ES cc-by-nc-nd Revista de Neurología 2021-01-01

Guillain-Barre Syndrome (GBS) is the most common cause of acute flaccid paralysis, with an incidence 0.81–1.89 cases per 100,000. With SARS-CoV-2 virus pandemic, major international vaccination campaigns continue to be carried out minimize total burden disease. This study aims report a case series consecutive GBS patients after during massive campaign in Mexico 2021. A single-center, observational subjects diagnosed by Asbury criteria from January 1 August 31, Including GBS-related symptoms...

10.1016/j.nerep.2021.100050 article EN cc-by Neuroimmunology Reports 2021-12-13

As SARS-CoV-2 vaccination is ongoing in Mexico and Guillain-Barre syndrome (GBS) cases have been reported, validation of Brighton criteria necessary. Moreover, epidemiology GBS differs from European North American countries.

10.33588/rn.7408.2021437 article EN Revista de Neurología 2022-01-01

ABSTRACT: Background: Up to 30% of patients with Guillain–Barré syndrome require mechanical ventilation and 5% die due acute complications ventilation. There is a considerable group that will need prolonged (considered as &gt;14 days) should be considered for early tracheostomy. The objective this study identify risk factors Methods: We prospectively analyzed diagnosis versus without clinical electrophysiological characteristics associated Results: Three hundred three were included; 29%...

10.1017/cjn.2023.23 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2023-02-15

Abstract Background: ABT-869 is a novel orally active, potent and selective inhibitor of VEGF PDGF receptor tyrosine kinases. potentiates the action P in number preclinical tumor models including breast carcinoma (BC). This study was conducted to assess pharmacokinetic (PK) interaction safety combined with weekly P, guide dosing randomized portion trial.Methods: Pts measurable chemotherapy naïve metastatic or unresectable locally advanced BC were eligible for this trial. Treatment consisted...

10.1158/0008-5472.sabcs-09-5076 article EN Cancer Research 2009-12-01

Guillain-Barré syndrome (GBS) represents the main cause of flaccid paralysis worldwide. Although most cases have a typical clinical presentation symmetric ascending with areflexia or hyporeflexia, this disease may present as multiple entities, therefore representing diagnostic challenge for physicians, who should consider these variants when assessing neuropathies. The pharyngeal-cervical-brachial (PCB) variant is defined by rapidly progressive oropharyngeal and cervicobrachial weakness...

10.7759/cureus.18788 article EN Cureus 2021-10-14

Late-onset limb-girdle myopathies pose a diagnostic challenge. The most common etiologies are inflammatory, followed by genetic and metabolic. Rare cases include dystrophies permanent (vacuolar), such as those associated with hypokalemic periodic paralysis (HypoPP). We present the case of 59-year-old male who initiated episodic acute severe weakness when he was 11, during which serum potassium levels <2.5 meq/L were revealed workup. Potassium reposition reversed these episodes. They occurred...

10.7759/cureus.18873 article EN Cureus 2021-10-18

Background: Bickerstaff brainstem encephalitis (BBE) presents with consciousness impairment, ataxia, ophthalmoplegia, and areflexia.Objective: We aim to describe the clinical, paraclinical, imaging features of patients BBE from a tertiary-referral neurological center.Methods: A case series was conducted an ambispective cohort Guillain-Barré syndrome (GBS) 2016 2021.Subjects ≥ 18 years who met Odaka et al.BBE criteria were eligible.Data collected included: age, gender, prior infection,...

10.24875/rmn.21000050 article EN cc-by-nc-nd DELETED 2022-02-21
Coming Soon ...