Jaehoon Seol

ORCID: 0000-0003-3441-4191
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About
Contact & Profiles
Research Areas
  • Sleep and related disorders
  • Sleep and Wakefulness Research
  • Physical Activity and Health
  • Health disparities and outcomes
  • Sleep and Work-Related Fatigue
  • Health and Wellbeing Research
  • Obesity, Physical Activity, Diet
  • Obstructive Sleep Apnea Research
  • Frailty in Older Adults
  • Older Adults Driving Studies
  • Circadian rhythm and melatonin
  • Urban Transport and Accessibility
  • Health and Well-being Studies
  • Stroke Rehabilitation and Recovery
  • Heart Rate Variability and Autonomic Control
  • Nutritional Studies and Diet
  • Nutrition and Health in Aging
  • Cardiovascular and exercise physiology
  • Musculoskeletal pain and rehabilitation
  • Diet and metabolism studies
  • Dietary Effects on Health
  • Adipose Tissue and Metabolism
  • Workplace Health and Well-being
  • EEG and Brain-Computer Interfaces
  • Traffic and Road Safety

University of Tsukuba
2016-2025

National Center for Geriatrics and Gerontology
2024-2025

Tsukuba International University
2019-2025

Tokyo Metropolitan Institute of Gerontology
2025

National Institute of Occupational Safety and Health
2023-2024

Chiba University
2023

Juntendo University
2023

Nagasaki University
2023

Japan Society for the Promotion of Science
2022

Deteriorating sleep quality and physical or mental fatigue in older adults leads to decreased of life increased mortality rates. This study investigated the effects time-dependent intake nicotinamide mononucleotide (NMN) on quality, fatigue, performance adults. randomized, double-blind placebo-controlled evaluated 108 participants divided into four groups (NMN_AM; antemeridian, NMN_PM; post meridian, Placebo_AM, Placebo_PM). NMN (250 mg) placebo was administered once a day for 12 weeks....

10.3390/nu14040755 article EN Nutrients 2022-02-11

Sleep insufficiency and sleep disorders pose serious health challenges. This study aimed to determine the potential discrepancy between subjective objective assessments, including latter made by physicians, analyzing a 421-participant dataset in Japan comprising multiple nights of in-home electroencephalogram (EEG) data questionnaire responses on habits or experiences. We employed logistic regression models examine which parameters physicians are paying attention when assessing...

10.1073/pnas.2412895121 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2025-01-16

Abstract Although recent studies have examined the bidirectional associations between physical activity and sleep parameters, few focused on older adults utilizing objective assessments, such as polysomnography. This micro-longitudinal observational study included 92 Japanese (aged 65–86 years) who underwent evaluations of quality using polysomnography completed subjective sleep-related questionnaires. Activity levels were assessed an accelerometer. Polysomnography, questionnaires,...

10.1038/s41598-022-19841-x article EN cc-by Scientific Reports 2022-09-13

Abstract Efforts to simplify standard polysomnography (PSG) in laboratories, especially for obstructive sleep apnea (OSA), and assess its agreement with portable electroencephalogram (EEG) devices are limited. We aimed evaluate the between a EEG device type I PSG patients OSA examine EEG-based arousal index’s ability estimate severity. enrolled 77 Japanese who underwent simultaneous monitoring. Combining pulse rate, oxygen saturation (SpO 2 ), improved staging accuracy. Bland–Altman plots,...

10.1038/s41598-024-53827-1 article EN cc-by Scientific Reports 2024-02-12

Women with ovulatory menstrual cycles show an increase in body temperature the luteal phase, compared follicular particularly during night. Several, albeit not all, studies reported higher energy expenditure phase phase. Q10 of biological reactions lies between 2.0 and 3.0, predicting a 7-12% when rises by 1°C. In this study, dependence was assessed comparing changes sleeping thermoregulation cycle 9 young females. Energy measured using metabolic chamber, which sleep recorded...

10.14814/phy2.14353 article EN cc-by Physiological Reports 2020-01-01

The relationship between manual dexterity and cognitive function among older adults is well known; however, few studies have focused on training that confirms load of in through functional near-infrared spectroscopy (fNIRS) verifies the effect training. This study examined effects home-based using a digital trail-making peg test device combining two conventional assessment tools namely, tests.For 12 weeks, 57 healthy aged 65-88 years participated parallel-group, randomized controlled trial,...

10.1186/s11556-023-00319-2 article EN cc-by European Review of Aging and Physical Activity 2023-04-22

The aim of this cross-sectional study was to investigate the influence replacing sedentary time with engaged in one two levels physical activity on sleep quality using an isotemporal substitution model. participants were 70 community-dwelling older Japanese adults (approximately 70% female). Physical types measured a triaxial accelerometer and categorized based intensity as sedentary, light-intensity, vigorous-intensity. Pittsburgh Sleep Quality Index assessed subjective quality. Objective...

10.1111/nhs.12647 article EN Nursing and Health Sciences 2019-09-16

Ingesting oolong tea or caffeine acutely increases energy expenditure, and tea, but not caffeine, stimulates fat oxidation. The acute effects of such as increased heart rate interference with sleep, diminish over 1-4 days, known tolerance. During each 14-day session the present study, 12 non-obese males consumed (100 mg 21.4 gallic acid, 97 catechins 125 polymerized polyphenol), mg), placebo at breakfast lunch. On day 14 session, 24-h indirect calorimetry polysomnographic sleep recording...

10.3390/nu12123671 article EN Nutrients 2020-11-28

We examined the associations between electroencephalogram (EEG)-based sleep characteristics and physical health parameters in general adults via a cross-sectional study recruiting 100 volunteers aged 30-59 years. Sleep were measured at home using portable multichannel electroencephalography recorder. Using k-means + clustering method, according to 10 EEG-based parameters, participants grouped into better (n = 39), middle 46), worse 15) groups. Comparing 50 among groups, we identified four...

10.1038/s41598-023-47979-9 article EN cc-by Scientific Reports 2023-12-08

Background Few studies have explored the relationship between macronutrient intake and sleep outcomes using daily data from mobile apps. Objective This cross-sectional study aimed to examine associations macronutrients, dietary components, parameters, considering their interdependencies. Methods We analyzed 4825 users of Pokémon Sleep Asken smartphone apps, each used for at least 7 days record objective parameters respectively. Multivariable regression quartiles macronutrients (protein;...

10.2196/64749 article EN cc-by Journal of Medical Internet Research 2025-01-30

Goals We aimed to examine patients with liver cirrhosis and compare their sleep characteristics those of healthy controls using innovative new electroencephalogram models. Background Sleep disturbance is a common disorder in cirrhosis. Many previous studies have been conducted on the topic questionnaire methods. However, polysomnographic quantitative assessments remain challenging because they are complicated difficult implement at clinical research level. Study recruited early disease low...

10.1101/2025.03.28.25324860 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2025-04-01

<title>Abstract</title> Background Driving is essential for maintaining independence. This study aimed to assess the mediating role of frailty status in association between exercise participation and traffic crashes among Japanese community-dwelling older drivers. Methods 2-year longitudinal included data 3,934 drivers aged ≥ 65 years Kasama City who did not require long-term care participated a postal survey 2019 2021 at baseline follow-up, respectively. The participants exercised least...

10.21203/rs.3.rs-5143153/v1 preprint EN Research Square (Research Square) 2025-04-02

Background: Good sleep is essential for a healthy, active life that supports disease prevention. Sleep debts caused by deprivation, irregular sleep, and insomnia increase the risk of metabolic syndrome, mood disorders, dementia, cancer. Today's lifestyles in developed countries are prone to debts, which has led social interventions aim reduce sleep-related health problems. ETAS®50 standardized extract Asparagus officinalis stem, been reported improve quality, maintain rhythms, relieve mental...

10.31989/ffhd.v15i4.1574 article EN Functional Foods in Health and Disease 2025-04-09

Abstract Introduction In Japan, over 12 million workers are engaged in night and shift work. Such irregular long working hours may lead to reduced or fragmented sleep, as well disruptions circadian rhythms, which have been associated with an increased risk of sleep disorders, prostate cancer, breast cancer. Previous research on workers’ has mainly relied questionnaires actigraphy, limited studies utilizing electroencephalography (EEG) analyze detailed architecture. Methods Six aged 23–42 at...

10.1093/sleep/zsaf090.0871 article EN SLEEP 2025-05-01

Significance Insomnia is a common symptom representing an important health burden. Widely prescribed hypnotic agents enhance the function of γ-aminobutyric acid (GABA), major inhibitory neurotransmitter. The ability to arouse and respond unexpected stimuli feature normal sleep, one concerns this class that patients may become physically and/or cognitively impaired while drug in effect. As new approach for treatment insomnia, orexin receptor antagonists have been recently approved, which...

10.1073/pnas.1907354116 article EN Proceedings of the National Academy of Sciences 2019-11-11

[Purpose] To examine the associations of exercise habits, particularly exercising in a group, with physical and cognitive functions community-dwelling older adults. [Participants Methods] A total 615 adults participated this cross-sectional study. We conducted three performance tests (grip strength, five times sit-to-stand, 5-meter walk tests) Five-Cog test (attention, memory, visuospatial, language, reasoning). investigated habits using questionnaires classified participants into groups as...

10.1589/jpts.33.15 article EN Journal of Physical Therapy Science 2021-01-01

Objective: This study aimed to determine whether the timing of exercise influenced effects home-based low-intensity stepping exercises on sleep parameters older adults. Method: For 8 weeks, 60 healthy adults participated in a randomized controlled trial, performing aerobic (70-80 bpm) for about 30 minutes every day at home, either morning (from waking until 12:00) or evening (18:00 bedtime). Results: In group, both subjectively and objectively measured latency significantly improved...

10.1177/0891988720924709 article EN Journal of Geriatric Psychiatry and Neurology 2020-05-20

The timing of exercise plays an important role in the effect on physiological functions, such as substrate oxidation and circadian rhythm. Exercise exerts different effects glycemic response to meal intake depending when performed. Here, we comprehensively investigated (morning or afternoon) glucose fluctuation basis several indices: variability over 24 h (24-h SD), J-index, mean amplitude excursions (MAGE), continuous overall net action (CONGA), detrended analysis (DFA). Eleven young men...

10.14814/phy2.14784 article EN Physiological Reports 2021-04-01

Fortified milk and resistance training (RT) increase muscle mass, strength, physical performance in older adults, but it remains unclear whether RT combined with aerobic (AT) would have stronger effects on these outcomes. The purpose of this study was to examine the (ART) fortified consumption adults.

10.1007/s12603-016-0864-1 article EN cc-by-nc-nd The journal of nutrition health & aging 2016-12-17

Abstract Background This study investigated whether daily physical activity of older adults, combined with social relationships, is associated the risk sleep disorder. Further, it determined a high level one variable low other, leads to significantly lower disorder than levels both. Methods The sample comprised 1339 community-dwelling Japanese adults: 988 in Study 1 and 351 2. range relationships were assessed using Physical Activity Scale for Elderly Lubben Social Network Scale,...

10.1186/s12877-021-02589-w article EN cc-by BMC Geriatrics 2021-11-03
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