A5004050829- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Management of metastatic bone disease
- Advanced Radiotherapy Techniques
- Spine and Intervertebral Disc Pathology
- Meningioma and schwannoma management
- Spinal Fractures and Fixation Techniques
- Lung Cancer Research Studies
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Bone Tumor Diagnosis and Treatments
- Cancer-related cognitive impairment studies
- Radiation Therapy and Dosimetry
- Neurogenesis and neuroplasticity mechanisms
- Sarcoma Diagnosis and Treatment
- Medical Imaging and Analysis
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Neurofibromatosis and Schwannoma Cases
- Advances in Oncology and Radiotherapy
Johns Hopkins Medicine
2016-2025
Johns Hopkins University
2016-2025
Sidney Kimmel Comprehensive Cancer Center
2013-2025
Johns Hopkins Hospital
2014-2025
Molecular Oncology (United States)
2023-2024
Radiation Oncology Associates
2019-2024
Princess Alexandra Hospital
2018-2023
University of Washington
2013-2019
National University Cancer Institute, Singapore
2018-2019
National University Health System
2018-2019
OBJECTIVE Although postoperative stereotactic body radiation therapy (SBRT) for spinal metastases is increasingly performed, few guidelines exist this application. The purpose of study to develop consensus promote safe and effective treatment patients with metastases. METHODS Fifteen oncologists 5 neurosurgeons, representing 19 centers in 4 countries having a collective experience more than 1300 spine SBRT cases, completed 19-question survey about practice. Responses were defined as follows:...
Vertebral compression fractures (VCFs) in patients with spinal metastasis can lead to destabilization and often carry a high risk profile. It is therefore important have tools that enable providers predict the occurrence of new VCFs. The most widely used tool for bone quality assessment, dual-energy x-ray absorptiometry (DXA), not available at patient's initial presentation has limited sensitivity. While Spinal Instability Neoplastic Score (SINS) been associated VCFs, it does take patients'...
While they account for one-fifth of new cancer cases, rare cancers are difficult to study. A higher than average degree uncertainty should be accommodated clinical as well population-based decision making. Rules rational making in conditions rigorously followed and would need widely informative trials. In principle, any piece evidence exploited cancers. Methodologies explicitly weigh combine all the available refined, Bayesian logic can instrumental this end. Likewise, Bayesian-design trials...
<h3>Importance</h3> The outcomes and factors that influence survival in patients with oligometastasis (OM) are not well understood have been described large-scale studies. <h3>Objective</h3> To evaluate overall progression-free (PFS), widespread progression (WSP) outcomes, from a pooled data set of 1033 OM treated stereotactic body radiotherapy (SBRT). <h3>Design, Setting, Participants</h3> Case series January 1, 2008, to December 31, 2016. dates analysis were April 2019 May 2020. setting...
Immune checkpoint blockade targeting programmed cell death protein 1 (PD-1) is emerging as an important treatment strategy in a growing list of cancers, yet its clinical benefits are limited to subset patients. Further investigation tumor-intrinsic predictors response and how extrinsic factors, such iatrogenic immunosuppression caused by conventional therapies, impact the efficacy anti-PD-1 therapy paramount. Given widespread use corticosteroids cancer management their immunosuppressive...
For brain metastases, the combination of neurosurgical resection and postoperative hypofractionated stereotactic radiotherapy (HSRT) is an emerging therapeutic approach preferred to prior practice whole-brain radiotherapy. However, mature large-scale outcome data are lacking.To evaluate outcomes prognostic factors after HSRT cavity in patients with metastases.An international, multi-institutional cohort study was performed 558 resected metastases treated between December 1, 2003, October 31,...