A5007742094- Cytomegalovirus and herpesvirus research
- Cervical Cancer and HPV Research
- Herpesvirus Infections and Treatments
- Viral-associated cancers and disorders
- Genital Health and Disease
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Parvovirus B19 Infection Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Respiratory viral infections research
- Oral microbiology and periodontitis research
- Reproductive tract infections research
- Polyomavirus and related diseases
- Virology and Viral Diseases
- Toxoplasma gondii Research Studies
- COVID-19 Clinical Research Studies
- Molecular Biology Techniques and Applications
- T-cell and Retrovirus Studies
- SARS-CoV-2 detection and testing
- Microbial infections and disease research
- Animal Disease Management and Epidemiology
- Osteomyelitis and Bone Disorders Research
- Head and Neck Cancer Studies
- Viral Infections and Immunology Research
University of Belgrade
2014-2024
Institut za Reumatologiju
2009-2023
Czech Academy of Sciences, Institute of Microbiology
2005-2023
Institut za zdravstvenu zaštitu dece i omladine Vojvodine
2022
Singidunum University
2020
Tufts University
2017
This study aimed to compare the levels of tumour necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β) and interleukin-6 (IL-6) between apical periodontitis lesions with different clinical histological features. Based on data history disease, 100 human were categorised as either asymptomatic or symptomatic lesions. According examination, divided into periapical granulomas radicular cysts. Pulp tissues 25 impacted wisdom teeth used controls. Homogenised tissue samples centrifuged...
Background: Oral reactivation of latent Herpes simplex virus (HSV) infection may easily occur in cancer patients. Virus can cause oral mucosa damage, worsen already existing lesions caused by stomatotoxic effect therapy and, whether symptomatic or asymptomatic, ample spreading and promote viral transmission. Methods: Polymerase chain reaction (PCR), cell‐culture direct immunofluorescence have been used to determine the frequency HSV 60 patients undergoing chemotherapy for different...
The objective of this case-control study was to test the existing hypotheses about factors related occurrence hepatocellular carcinoma in population Belgrade (Serbia).The investigation conducted between 2004 and 2007 consisted 45 newly diagnosed, histologically confirmed patients 90 individually gender- age-matched hospital controls. Conditional univariate multivariate logistic regression analyses were applied.A highly statistically significant association (P = 0.001) demonstrated HBsAg...
To investigate whether apical periodontitis lesions infected by Epstein-Barr virus (EBV) exhibit higher levels of oxidative stress biomarkers [8-hydroxydeoxyguanosine (8-OHdG) and oxidized glutathione (GSSG)] bone resorption regulators [receptor activator nuclear factor (NF-κB) ligand (RANKL) osteoprotegerin (OPG)] compared to EBV-negative periapical healthy pulp tissues.The experimental group consisted 30 EBV-positive collected in conjunction with apicoectomy. The tissues 20 impacted third...
Objectives This study aimed to analyse Epstein–Barr virus ( EBV ) and human cytomegalovirus HCMV viral loads in symptomatic asymptomatic apical periodontitis lesions, determine levels of TNF ‐α, IL ‐1β ‐6 these lesions investigate a possible correlation between herpesviral copy numbers proinflammatory cytokines. Materials Methods A total 100 samples were subjected analysis by nested polymerase chain reaction PCR TaqMan real‐time . The concentrations determined ELISA method. SPSS software was...
Abstract Disseminated neonatal herpes simplex virus (HSV) infection is characterized by progressive multiple organ failure and high mortality rates. It can result from with either HSV-1 or HSV-2. We report a case of disseminated that was caused
Abstract The aim of this study was to estimate substitution rate and imprints natural selection on parvovirus B19 genotype 1. Studied datasets included 137 near complete coding genomes (positions 665 4851) for phylogenetic analysis 146 214 partial analyses in open reading frames ORF1 ORF2, respectively, collected 1973–2012 including 9 newly sequenced isolates from Serbia. Phylogenetic clustering assigned majority studied G1A. Nucleotide total DNA 1.03 (0.6–1.27) x 10 −4...
The oncogenicity of the human cytomegalovirus (CMV) is currently being widely debated. Most recently, mounting clinical evidence suggests an anti-cancer effect via CMV-induced T cell-mediated tumor destruction. However, data were mostly obtained from single-center studies and in vitro experiments. Broad geographic coverage required to offer a global perspective. Our study examined correlation between country-specific CMV seroprevalence (across 73 countries) age-standardized incidence rate...
Abstract Persistent infection with one or more highly oncogenic human papillomaviruses (HPVs) high-risk-HPV (HR-HPV) is necessary but not a sufficient aetiological agent for the development of cervical neoplasia. A number viral, host, environmental and behavioural factors are suggested to be associated progression disorder. This study aimed evaluate impact cofactors on disorders in HR-HPV-infected women Serbia. total 541 have been tested by PCR presence HPV cervix. genotypes were determined...
Abstract The presence of bovine parainfluenza virus type 3 (BPIV3) was examined in 119 nasal swabs collected from cattle with severe respiratory infection. All samples were conducted for isolation on the MDBK cell line. cytopathic effect observed after 48h to 72h cells inoculated eight (8/119; 6.7%). confirmation isolated strains BPIV3 done by virus-neutralization test. In addition, all also using RT-PCR primers specific part HN gene. detected 6.7%) that positive upon isolation. molecular...
Abstract Background Although cytomegalovirus (CMV) is not considered tumorigenic, there evidence for its oncomodulatory effects and association with hematological neoplasms. Conversely, a number of experimental clinical studies suggest putative anti-tumour effect. We investigated the potential connection between chronic CMV infection in patients B-lymphocyte (B-cell) malignancies retrospective single-center study extracted relevant data on prevalences incidences B-cell cancers world over....
Abstract Certain factors lead to increased reactivation of JC virus (JCV) and immunodeficiency seems be the most important. JCV isolates can classified into eight different genotypes several subtypes based on nucleotide difference in VP1 gene. are strongly associated with particular ethnic groups frequently used as genetic markers for human evolution migration. The aim this study was determine frequency urinary shedding genotype distribution Serbia among patients infected HIV healthy donors....
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, has been evolving rapidly causing emergence of new variants and health uncertainties. Monitoring evolution virus was utmost importance public interventions development national global mitigation strategies. Here, we report data on variants, their distribution, dynamics in a 3-year study conducted from March 2020 to end January 2023 Republic Serbia. Nasopharyngeal oropharyngeal swabs 2,398...
Severe acute respiratory infections (SARI) are estimated to be the cause of death in about 19% all children younger than 5 years globally. The outbreak coronaviral disease (COVID-19) caused by SARS-CoV-2, increased considerably burden SARI worldwide. We used data from a vaccine effectiveness study identify factors associated with SARS CoV-2 infection among hospitalized patients. recruited patients at 3 hospitals Serbia 7 April 2022–1 May 2023. collected demographic and clinical using...
The potential problems of DNA extraction from formalin‐fixed paraffin‐embedded (FFPE) tissue samples and amplification efficiency Human papilloma virus (HPV) may occur in the molecular studies head neck squamous carcinoma (HNSCC). aim this study was to compare HPV detection rate FFPE tissues oral, oropharyngeal, hypopharyngeal, laryngeal cancers using two silica‐based kits three methods. A total 50 specimens HNSCC were analyzed. quality quantity extracted tested by spectrophotometry....