This study assessed pronuclear formation, the chromosomal constitution, and developmental capacity of bovine zygotes formed by intracytoplasmic injection oocytes with sperm, treated or not dithiothreitol (DTT). Oocytes were matured in vitro for 22–24 h then centrifuged so that prepared swim-up presence absence 5 mM DTT, could be injected into cleared area ooplasm. Injected activated treatment μM ionomycin (5 min) and, after a 3-h interval, 1.9 6-dimethylaminopurine (DMAP) 3 h. They...

Purpose: This study measured the knowledge and use of herbs among Hispanics assessed their experiences when discussing herb with physician. Methods: Self-administered questionnaires were collected from 620 Hispanic patients seeking treatment in urban health centers. Results: Most (80.3%) reported using herbs. Herb users more comfortable speaking Spanish (91.9% vs 80.2%) had been United States less than 5 years (47.0% 29.4%). More considered as drugs (60.5% 39.6%). Users aware that could harm...

Background:Glaucoma (POAG) is a kind of neurodegenerative disease known to be closely associated with stress and adverse quality life (QOL). Stress has also been shown involved in etiopathogenesis primary open angle glaucoma (POAG). Complementary treatment form Meditation reported improve QOL, brain oxygenation decrease markers stress. With this premise, randomized controlled trial was carried out assess the effect on intraocular pressure, subjective QOL objective patients POAG....

Fibromyalgia is a multi-symptomatic disorder characterized by generalized pain. The pathophysiology of fibromyalgia supposedly an interplay between central nervous system hyper-responsiveness, autonomic dysfunction, and peripheral In this cross-sectional study, the objective was to assess sensitization activity in patients with compared control. Fifty adults diagnosed modified American College Rheumatology 2010 criteria equal number age- sex-matched controls participated study urban tertiary...

Infantile central palsy (CP) is caused due to damage the immature developing brain usually before birth, leading altered topography and biochemical milieu. CP a life-limiting disorder, which causes changes in sensory, motor, cognitive, behavioral functioning. Understanding its pathophysiology complex, current therapeutic modalities, oral medication, surgical treatment, physical therapy, rehabilitation provide minimal relief. As plastic, it has an inherent capacity adapt activity; thus,...

Introduction: Motor control for voluntary movement involves the orchestrated activity of motor cortical areas, which activate approximately one to two seconds before onset. This preparatory neural activity, termed Bereitschaftspotential (BP), reflects readiness circuits initiating movement. BP has been linked parameters such as force and rate contraction; however, influence precision on components is less understood. study aims investigate how affects characteristics, providing insights into...

Background Parkinson’s disease (PD) is a neurodegenerative disorder that affects both motor and non-motor functions of the body. Recently, scientists have attributed gut dysbiosis plays crucial role in development progression PD. Purpose In this study, we aim to determine probiotic supplementation on dysbiosis, inflammatory responses at systemic level, neurodegeneration deficits. Methods To develop rat model PD, 6-hydroxydopamine was bilaterally injected into striatum. Starting from first...

In healthy subjects, the intraocular pressure (IOP) is maintained by a dynamic equilibrium between continuous production of aqueous humor ciliary bodies and outflow through two drainage pathways: trabecular meshwork uveoscleral outflow. Here, we hypothesized that yogic ocular exercises, including extraocular muscles exercise, modified Tratak Kriya (mTK), might reduce IOP as well stress improve quality life (QoL) in patients with glaucoma.A parallel two-arm randomized controlled trial (RCT)...

Objective To assess school policies, built environment and practices for prevention control of non-communicable diseases in schools Delhi, India. Methods School environments policies were assessed using a structured observation checklist 10 private 9 government which randomly selected from all 184 co-educational with primary to senior secondary level education A self-administered questionnaire was also completed by teachers each (n = 19) capture information specific policies. Surveys...

Background Body mass index (BMI) is an important indicator of overweight and obesity. Unlike BMI, body fat percentage (BF%) can be utilized to estimate composition regardless weight height. The association between BMI BF%, as well the impact age gender, may help prevalence obesity more clearly. This study aimed assess relationship examine effect gender on this relationship, establish linearity/curvilinearity relationship. Methodology analysis 1,150 participants in various institutional...

Abstract Background and aims As the understanding of food addiction increases, there is a need to explore occurrence this condition in different population groups. This exploratory study aimed assess sample respondents from India using Hindi version Yale Food Addiction Scale (YFAS). Methods The language scale was developed back-translation methodology. Subsequently, an online questionnaire-based conducted convenience sampling which presented YFAS. Results From 376 (median age 19 years, 42.8%...

Knowledge about the key steps in "research methodology" is necessary for all postgraduate students who are enrolled medical profession. The objective of present study was to plan, design, and implement a participant-centric skill development activity inculcate principles components research methodology. It included 3 goal-oriented component group exercises, namely, 1) framing question, 2) critiquing article, 3) writing protocol. Out 25 eligible our department, 20 participated three they were...

Metabolic responses to barley (Hordeum vulgare) were studied in six healthy human subjects (five male, one female). The trial comprised two dietary periods, control and experimental, of four weeks each, separated by a washout period week. diet was which the subject normally accustomed. In experimental diet, part daily cereal intake replaced 100 g whole flour. periods random sequence cross-over design used. A meal tolerance test using 50g carbohydrate portion white bread performed at...

Parkinson's disease (PD) is second most common neurodegenerative disorder, which a progressive motor that affects 10 million people worldwide and around 5.5 Indian.The hallmark neuropathology in PD are damage to dopaminergic neurons located the pars compacta of substantia nigra (SN) project striatum alpha synuclein containing inclusion bodies surviving neurons, resulting impairments, e.g., tremors, bradykinesia (slow movement), poor balance, rigidity difficulty walking, as well non-motor...

Recording cortical potentials prior to movement (bereitschaftspotentials, BP) offer a good non invasive method for studying activity of motor related cortices in Parkinson's Disease (PD). Dopaminergic medications provide some symptomatic relief advanced stages but they do not stop the progression disease. Assessing BP may be idea see response anti PD drugs. It remains unclear whether also improve even disease.In this study we recorded scalp patients with varying grades severity relationship...