A5000188504- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- Advanced Nanomaterials in Catalysis
- RNA Interference and Gene Delivery
- Polymer Surface Interaction Studies
- Mesoporous Materials and Catalysis
- Fatigue and fracture mechanics
- Aluminum Alloys Composites Properties
- Dendrimers and Hyperbranched Polymers
- Magnesium Alloys: Properties and Applications
- Extracellular vesicles in disease
- Nanocluster Synthesis and Applications
- Radioactive element chemistry and processing
- Gold and Silver Nanoparticles Synthesis and Applications
- Metal-Organic Frameworks: Synthesis and Applications
- Microstructure and mechanical properties
- Advanced Welding Techniques Analysis
- Photodynamic Therapy Research Studies
- Graphene and Nanomaterials Applications
- Groundwater and Isotope Geochemistry
- Hydrocarbon exploration and reservoir analysis
- Biosensors and Analytical Detection
- Lanthanide and Transition Metal Complexes
- High Temperature Alloys and Creep
Chongqing University
2016-2025
Guizhou Normal University
2018-2024
Wuhan University of Technology
2020-2022
Sinopec (China)
2022
Institute of Geochemistry
2021
Chinese Academy of Sciences
2021
Bioengineering Center
2016-2020
First Affiliated Hospital Zhejiang University
2020
Zhejiang University
2020
Åbo Akademi University
2013-2016
Photothermal treatment (PTT) involving a combination of therapeutic modalities recently emerged as an efficient alternative for combating biofilm. However, PTT-related local high temperature may destroy the surrounding healthy tissues. Herein, we present all-in-one phototherapeutic nanoplatform consisting l-arginine (l-Arg), indocyanine green (ICG), and mesoporous polydopamine (MPDA), namely, AI-MPDA, to eliminate already-formed The fabrication process included surface modification MPDA with...
Theranostic agents for combined chemo-photothermal therapy have attracted intensive interest in the treatment of multi-drug resistance (MDR) cancer therapy. However, development simple theranostic as dual hosts both heat and a high payload chemotherapeutic remains big challenge. Herein, mesoporous polydopamine nanoparticles (MPDA) were successfully developed with properties DOX (up to 2000 μg mg−1) drug efflux inhibitor TPGS (D-α-tocopheryl polyethylene glycol 1000 succinate), well strong...
Well known for the adhesive property, mussel-inspired polydopamine (PDA) has been shown to enhance performance in a wide range of adsorption-based applications. However, imparting porous nanostructures PDA materials enhanced loading capacities not demonstrated even when surfactants were present synthesis. Herein, we report on preparation mesoporous particles (MPDA) based assembly primary and Pluronic F127 stabilized emulsion droplets water/1,3,5-trimethylbenzene (TMB) interfaces. The key...
With the rapid development of bionic science and manufacturing technology, superhydrophobic surfaces have received extensive attention research. However, cumbersome steps, high cost, fluorine pollution, poor durability greatly restrict its commercial promotion application. Here, a simple spraying method is used to construct wear-resistant coatings on various substrates such as glass, filter paper, copper sheets, polyethylene terephthalate films, using an integrated fluorine-free suspension...
In recent years, photothermal materials that can convert light into heat energy have attracted extensive attention. this work, we report a simple and effective approach to construct self-cleaning superamphiphobic fabric. Dopamine (DA) self-polymerize polydopamine (PDA) adhere the surface of cotton fabric as secondary reaction platform. Then, SiO2 nanoparticles were in situ grown on PDA@fabric by sol-gel method. The PDA clusters not only provide good conversion performance but also be...
Reactive oxygen species (ROS) generators are sparking breakthroughs in sensitization and treatment of therapy-resistant tumors, yet the efficacy is drastically compromised by limited substrate concentrations, short lifetimes free radicals, restricted oxidative damage. Herein, a flower-like nanozyme with highly permeable leaflets accommodating catalytic metal sites was developed to address challenges boosting product accessibility. In formation zeolite imidazole framework, cobalt ions...
Cyclic deformation of magnesium single crystal under fully reversed tension–compression along the [0 0 1] direction at a strain amplitude 0.5% was investigated in ambient air. In situ light microscopy twins conducted on prismatic plane. Fundamental morphology evolution twinning–detwinning–retwinning characterized situ. The critical resolved shear stress twinning found to be ∼2.4 MPa. With increasing loading cycles, activity exhausted and residual accumulated. During detwinning each cycle,...
The interaction between DNA and mesopores is one of the basic concerns when mesoporous silica nanoparticle (MSN) used as a carrier. In this work, we have synthesized type that has Fe3O4 inner core shell. This magnetic (denoted M-MSN) offers us convenient platform to manipulate adsorption desorption processes it can be easily separated from solution by applying field. behavior studied function time in chaotropic salt solution. maximum amount adsorbed determined high 121.6 mg/g. We also...
A composite nanocarrier system integrating the porous structure of mesoporous silica nanoparticles (MSNs) and adhesive property polydopamine (PDA) for loading release hydrophilic drugs is reported. Amino group functionalization facilitates oxidant-induced surface polymerization dopamine in confined space mesopores by Schiff base/Michael addition reaction a mild synthesis. As consequence, MSN@PDA particles have an average pore size 4.0 nm, particle diameter ∼70 as well thin layer coating on...
Abstract The development of wound dressings with combined antibacterial activities and pro‐healing functions has always been an intractable medical task for treating bacterial infection. Herein, a novel injectable hybrid hydrogel dressing is developed, which doped nitric oxide (NO) donor (N,N’‐di‐sec‐butyl‐N,N’‐dinitroso‐1,4‐phenylenediamine, BNN6) loaded two‐dimensional polydopamine nanosheets (PDA NS). matrix in situ formed through dynamic Schiff base crosslinking between...
Currently, the simple integration of multiple therapeutic agents within a single nanostructure for combating multidrug resistance (MDR) tumors yet remains challenge. Herein, we report photoresponsive nanocluster (NC) system prepared by installing polydopamine (PDA) nanoparticle clusters on surface d-α-tocopheryl poly(ethylene glycol) 1000 succinate (TPGS) (a drug efflux inhibitor) micelles solubilized with IR780 photosensitizer) to achieve combined chemotherapy (CT)/photothermal therapy...
Abstract The use of reactive oxygen species (ROS) generators based on single‐atom catalysts (SACs) has been an emerging strategy for mediating tumor therapy, however, the current systems suffer from low mass transport efficiency. Here, a novel morphology fragmentation is developed to fabricate flower‐like SAC nanozymes with greatly improved 3D accessibility active sites. Specifically, coordinationally polymerized zeolite imidazole framework acts as polyphenol oxidase‐like enzyme catalyze in...
Abstract Despite the accuracy advantages of photothermal therapy (PTT), heat stress‐initiated free radicals and damage‐activated immune cells form a malignant positive feedback cycle following light irradiation. Herein, 2D allomelanin nanomodulator with perpendicularly oriented oligomer planes is prepared by guidance DNA to achieve timely scavenging reactive oxygen species (ROS) for inflammation prognosis control PTT. A large exposure degree phenol groups effective transfer delocalized...