A5027660285- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Vector-borne infectious diseases
- Insect Pest Control Strategies
- Insect symbiosis and bacterial influences
- Aquaculture disease management and microbiota
- Virology and Viral Diseases
- Viral Infections and Immunology Research
- Vector-Borne Animal Diseases
- Leptospirosis research and findings
- Polyamine Metabolism and Applications
- Cytomegalovirus and herpesvirus research
- Infectious Encephalopathies and Encephalitis
- Malaria Research and Control
- COVID-19 epidemiological studies
- Melamine detection and toxicity
- Viral Infections and Outbreaks Research
- Fire effects on ecosystems
United States Naval Medical Research Unit SOUTH
2011-2023
Naval Medical Research Command
2004-2009
United States Army Medical Research Institute of Infectious Diseases
2007
Ministry of Health
2004
Over half the world's population is at risk for viruses transmitted by Aedes mosquitoes, such as dengue and Zika. The primary vector, aegypti, thrives in urban environments. Despite decades of effort, cases geographic range Aedes-borne (ABVs) continue to expand. Rigorously proven vector control interventions that measure protective efficacy against ABV diseases are limited Wolbachia a single trial Indonesia do not include any chemical intervention. Spatial repellents, new option efficient...
Eastern equine encephalitis virus (EEEV) causes severe neurologic disease in North America, but only two fatal human cases have been documented South America. To test the hypothesis that alphavirus heterologous antibodies cross-protect, animals were vaccinated against other alphaviruses and challenged up to 3 months later with EEEV. Short-lived cross-protection was detected, even absence of cross-neutralizing antibodies. assess exposure EEEV Peru, sera from acutely ill healthy persons tested...
Between May and October 2002, a cluster of acute febrile illnesses occurred in the subtropical Andean foothills Peru. Serologic evidence villages where disease had been documented showed that prevalence IgM antibody to Leptospira ranged from 6% 52%, spotted fever group (SFG) rickettsia 10% 19%, Coxiella burnetii 1% 15%. Measurement IgG antibodies for SFG rickettsiae suggested this was endemic. In contrast, against C. were largely absent. humans, microagglutination tests identified pathogenic...
Although encephalomyocarditis virus (EMCV) infection has been commonly documented among domestic animals, less is known about EMCV transmission humans. Recently, we described the isolation of from two febrile patients in Peru. To further investigate Peru, screened reporting to health clinics Peru for serological evidence recent infection. We also conducted a survey EMCV-neutralizing antibodies city Iquitos, located Amazon basin department Loreto, Additionally, serum rodents collected 10...
While human illness associated with hantavirus infection has been documented in many countries of South America, evidence for transmission Peru limited to the isolation Rio Mamore virus from a pigmy mouse rat (Oligoryzomys microtis) Amazon city Iquitos. To address possibility exposure region, we screened febrile patients reporting health clinics Iquitos 2007 2010 serological recent infection. In addition, conducted survey hantavirus-reactive IgG among healthy participants residing and rural...
Group C orthobunyaviruses (GRCVs) are a complex of viruses in the genus Orthobunyavirus and associated with human febrile disease tropical subtropical areas South Central America. While numerous GRCVs have been isolated from mosquitoes, animals, humans, genetic analysis these is limited. In this study, we characterized 65 GRCV isolates patients identified through clinic-based surveillance northern southern Peruvian Amazon. A 500 base pair region S segment 750 regions M L segments were...
Abstract Over half the world’s population is at risk for viruses transmitted by Aedes mosquitoes, such as, dengue and Zika. The primary vector, aegypti , thrives in urban environments. Despite decades of effort, cases geographic range -borne (ABV) continue to expand. Rigorously proven vector control interventions that measure protective efficacy against ABV diseases limited Wolbachia a single trial Indonesia, do not include any chemical intervention. Spatial repellents, new option efficient...
Zika virus (ZIKV) emerged and spread rapidly in South American countries during 2015. Efforts to diagnose ZIKV infection using serological tools were challenging dengue-endemic areas because of antigenic similarities between both viruses. Here, we assessed the performance an in-house developed IgM antibody capture enzyme-linked immunosorbent assay (MAC-ELISA) plaque reduction neutralization test (PRNT) infection. Acute convalescent paired serum samples from 51 patients who presented with...
Objective. To develop and validate a cell suspension method using Vero 76 cells for culturing Zika virus (ZIKV) based on infection of detached freshly seeded cells. Material methods. Three different multiplicities ZIKV were used to compare this novel the standard confluent monolayer method. In addition, we preliminary validated well-characterized positive negative clinical samples. The monolayermethod was as reference method, viral isolation confirmed by ZIKV-specific RT-PCR. We estimated...
ABSTRACT. The isolation of Zika virus (ZIKV) from serum suspected human cases for diagnostic purposes can be challenging due to infrastructure constraints laboratory testing technology. Therefore, as an alternative method, the objective this study was evaluate a random sample oropharyngeal swabs diagnosis ZIKV infection among patients with symptoms arboviral and respiratory illness. results revealed that RNA could detected by reverse transcriptase polymerase chain reaction (RT-PCR) assay...