A5053473750- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Cancer, Hypoxia, and Metabolism
- Epigenetics and DNA Methylation
- Cytokine Signaling Pathways and Interactions
- Advanced Biosensing Techniques and Applications
- Multiple Sclerosis Research Studies
- Angiogenesis and VEGF in Cancer
- Optical and Acousto-Optic Technologies
- Acute Lymphoblastic Leukemia research
- Microfluidic and Capillary Electrophoresis Applications
- Mast cells and histamine
- Occupational Health and Safety Research
- Arsenic contamination and mitigation
- Traumatic Brain Injury Research
- Psoriasis: Treatment and Pathogenesis
- Photorefractive and Nonlinear Optics
- Advanced Nanomaterials in Catalysis
- Saffron Plant Research Studies
- Biochemical effects in animals
- Cannabis and Cannabinoid Research
- PI3K/AKT/mTOR signaling in cancer
- Diabetes and associated disorders
- Curcumin's Biomedical Applications
- Histone Deacetylase Inhibitors Research
Tabriz University of Medical Sciences
2019-2023
Kerman University of Medical Sciences
2017-2021
Isfahan University of Technology
2009
The mu-opioid receptor, encoded by receptor gene (OPRM1), has an important role in the development of addiction to opioids. Its aberrant reduction on cell membrane is responsible, at least part, for tolerance and physical dependence.The present study was designed identify relationship between opium consumption epigenetic mechanisms involved addiction.Genomic DNA extracted from peripheral blood 66 men with use disorder 57 healthy as a control group. Genomic DNAs were treated sodium bisulfite...
Aberrant patterns in promoter methylation of tumor-suppressor genes and posttranslational modifications histone proteins are considered as major features malignancy. In this study, we aimed to investigate three (BRCA-1, MGMT, P16) marks (H3K9ac, H3K18ac, H4K20me3) patients with breast tumors. This case-control study included 27 malignant tumors (MBT) 31 benign (BBT). The methylation-specific PCR was used for determining BRCA-1, P16 genes. Western blot analysis performed detect lysine...
As a novel cause of pneumonia, coronavirus disease 2019 (COVID-19) has rapidly progressed worldwide Previ-ous studies have indicated COVID-19 patients with diabetes show higher mortality rates and more severe infection an increased requirement for intensive care hospital length stay (LOS) compared to non-diabetic The present study aimed investigate the association outcome severity in hospitalized case-control included 268 diagnosed who were Ayatollah Khoyi Hospital, Khoy, Iran Diabetes was...
The reports show that rutin has good potentials as an anticancer agent; however, poor bioavailability due to its low aqueous solubility. present study was aimed at preparing and evaluating physicochemical properties well the activities of nanocrystals (RNs). RNs were prepared via ultrasonication method. then physicochemically characterized by conventional techniques. cytotoxic effect free on HN5 head neck squamous carcinoma cell line assessed. HGF1-PI1 cells normal oral treated RNs. Cells...
Introduction: Metformin is a common drug for the treatment of diabetic patients. This has been shown to have anti-cancer effects. acts through AMPK/mTOR pathway against cancer cells. We hypothesized that metformin, in combination with laser as photodynamic therapy (PDT), may increase cytotoxicity treatment. study aimed evaluate effect and mechanism metformin combined irradiation on head neck Methods: The was evaluated using cells (HN5 cells) oral cavity normal (HUGU) vitro . Cell viability...
Background: In this work, an aptamer-based biosensor was successfully developed based on the salt-induced gold nanoparticle (AuNP) aggregation phenomenon for detection of carbohydrate antigen 125 (CA125), which is important tumor marker ovarian cancer. Materials and Methods: Citrate-coated AuNPs are relatively highly dispersed NPs. presence different salts, electrostatic stability NPs reduced, depending type salt its concentration, degrees occur. On other hand, aptamer easily adsorbed AuNP...
The appearance of precursor fields in a causally dispersive dielectric is due to the interrelated effects phase dispersion and frequency dependent attenuation medium. Until now, rigorous studies these transient have been performed showing evolution precursors their unique penetrating features that can be used imaging material identification. To able use for identification we need know dependance on medium parameters. purpose this paper study Sommerfeld Brillouin passive Lorentzian media...