A5113129450- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Endometriosis Research and Treatment
- Uterine Myomas and Treatments
- Gynecological conditions and treatments
- Reproductive System and Pregnancy
- Cancer-related molecular mechanisms research
- Bone Metabolism and Diseases
- Pregnancy and preeclampsia studies
- Cancer Genomics and Diagnostics
- Estrogen and related hormone effects
- Viral-associated cancers and disorders
- PI3K/AKT/mTOR signaling in cancer
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cancer Mechanisms and Therapy
- Gastric Cancer Management and Outcomes
- Muscle and Compartmental Disorders
- Pregnancy-related medical research
- Prenatal Screening and Diagnostics
- Biomedical and Chemical Research
- Pelvic and Acetabular Injuries
- Bone health and osteoporosis research
- Minimally Invasive Surgical Techniques
- Intraperitoneal and Appendiceal Malignancies
Mie University
2018-2025
Mie University Hospital
2023-2024
Ovarian cancer has a poor prognosis, and screening methods have not been established. Biomarkers based on molecular genetic characteristics must be identified to develop diagnostic therapeutic strategies for all types, particularly ovarian cancer. The present study aimed evaluate the usefulness of analysis cervical endometrial liquid-based cytology (LBC) specimens detecting somatic mutations in patients with data 19 treated between August 2019 July 2022 were analyzed. LBC from cervix...
Adverse events associated with long-term bevacizumab administration for ovarian cancer have been poorly documented in Japan. This study aimed to evaluate the adverse of combined chemotherapy treating primary and recurrent epithelial Japan.In this single-center retrospective study, we analyzed data patients advanced treated between January 2013 November 2019. Statistical analyses were performed using Fisher's exact test Kaplan-Meier method.A total 46 included follow-up time was 30 months. The...
To investigate the recurrence rate, live-birth and treatment outcomes of levonorgestrel-releasing intrauterine device (LNG-IUD) for management atypical endometrial hyperplasia (AEH) or Grade-1 cancer (EC) in patients who desire fertility-sparing those seeking conservative without fertility preservation.We prospectively enrolled nine from a single institution between April 2009 September 2013 were followed up 60 months after LNG-IUD insertion.The median patient age was 35 (range: 29-39)...
Our goal was to compare the treatment outcomes of open-abdominal radical hysterectomy (O-RH) and total laparoscopic (TLRH) with vaginal cuff creation without using a uterine manipulator in stage IB1-B2 (tumor size < 4 cm) cervical cancer cases. In this retrospective multicenter analysis, 94 patients who underwent O-RH or TLRH six hospitals Japan between September 2016 July 2020 were included; 36 TLRH. Propensity score matching performed because tumor diameter large, positive cases lymph...
To the best of our knowledge, there are no useful screening methods for early detection endometrial cancer in asymptomatic individuals. The present study evaluated usefulness genetic analysis liquid-based cytology (LBC) specimens by assessing whether pathological mutations detected tissue sections were LBC from cervix and uterus. primary endpoint was cervical cancer. Endometrial thickening (>11 mm) assessed using transvaginal ultrasonography 60% cases adenocarcinoma 50% cases. In 70% cases,...
Purpose: We recently demonstrated the efficacy of tadalafil treatment for fetal growth restriction (FGR). This study aimed to evaluate utility serum placental factor (PlGF) level predicting FGR. Materials and methods: The correlations between PlGF velocity were retrospectively assessed in nine pregnant women receiving FGR before 30 weeks' gestation. Results: Median gestational age was 26 weeks (range 26-28 weeks), median deviation estimated weight from standard -2.1 deviations (SD) (-2.2...
We evaluated the efficacy of minodronic acid for osteoporosis prevention after bilateral oophorectomy gynaecologic disease in premenopausal women. Bone mineral density (BMD) and young adult mean (YAM) data from lumbar vertebrae femur bone alkaline phosphatase (BAP)/tartrate-resistant 5 b (TRACP b) were obtained 101 patients. The primary endpoint was prevention. Fifty-five 31 patients assigned to medication no groups, respectively. decrease BMD YAM increase BAP/TRACP-5b significantly more...
<h3>Abstract</h3> Background/Aim: This study aimed to compare laparoscopy with laparotomy and evaluate the effectiveness of a laparoscopic combined retroperitoneal transperitoneal approach for para-aortic lymphadenectomy in patients endometrial cancer. Patients Methods: In this single-center retrospective study, cancer who underwent between December 2016 November 2019 were analyzed. The patient’s clinical pathologic data procured from medical records. Statistical analyses performed using...
Background: This study aimed to evaluate the effectiveness of pelvic and para-aortic lymphadenectomy in patients with advanced epithelial ovarian cancer following neoadjuvant chemotherapy. Methods: single-center retrospective analyzed who underwent interval debulking surgery between December 2008 March 2020. Patients’ clinical pathological data were obtained from medical records. Statistical analyses performed using Fisher’s exact Mann–Whitney U test. Results: Overall, 33 22 included...
This study determines whether the use of a portable interface pressure sensor (Palm Q) for robotic surgery could prevent compartment syndrome.In present single center, non-trial observational study, patients diagnosed with gynecological diseases between April 2015 and August 2020 treated laparoscopic or were enrolled. We assessed 256 cases involving performed in lithotomy position an operative time >4 h. The Palm Q device was placed preoperatively on both sides patients' lower legs. measured...
Background/Aim: Ovarian clear cell carcinoma (CCC) is associated with a poor prognosis and resistant to chemotherapy. The aim of this study was investigate the CCC in Mie prefecture identify prognostic factors. Patients Methods: In multi-center retrospective study, we analyzed data patients between February 2012 December 2020. were staged according International Federation Gynecology Obstetrics (FIGO) 2014 system. Statistical analyses performed using Kaplan–Meier method compared two groups...