- Corrosion Behavior and Inhibition
- Enzyme Catalysis and Immobilization
- Conducting polymers and applications
- Computational Drug Discovery Methods
- Graph theory and applications
- Graphene and Nanomaterials Applications
- Dendrimers and Hyperbranched Polymers
- Concrete Corrosion and Durability
- Electrochemical sensors and biosensors
- Bone Tissue Engineering Materials
- Nanoparticles: synthesis and applications
- Analytical Chemistry and Sensors
- Molecular spectroscopy and chirality
- biodegradable polymer synthesis and properties
- Innovative Microfluidic and Catalytic Techniques Innovation
- Synthesis and Properties of Aromatic Compounds
- Advanced Nanomaterials in Catalysis
- Dental materials and restorations
- Click Chemistry and Applications
- Gas Sensing Nanomaterials and Sensors
- Graphene research and applications
- Chemical Synthesis and Analysis
- Fullerene Chemistry and Applications
- Catalysts for Methane Reforming
- Catalysis for Biomass Conversion
Babeș-Bolyai University
2015-2024
Spitalul Clinic Județean de Urgență Cluj-Napoca
2016-2023
Iuliu Hațieganu University of Medicine and Pharmacy
2014
To investigate the comparative effects of prenatal exposure to silver nanoparticles (AgNPs) functionalized with citrate and polyphenols on spatial cognition also nitro-oxidative stress apoptosis in hippocampus cerebellum offsprings.Pregnant Wistar rats were orally administered substances from day 10 gestation until 21. Six weeks postpartum, six male offsprings each group used for behavioral evaluation determination oxidative apoptosis.Both groups exhibited hyperactivity anxiety especially...
Lipase B from Candida antarctica immobilized by covalent binding on sebacoyl-activated chitosan-coated magnetic nanoparticles proved to be an efficient biocatalyst (49.2-50% conversion in 3-16 h and >96% enantiomeric excess) for the enzymatic kinetic resolution of some racemic heteroarylethanols through transesterification with vinyl acetate. Under optimal conditions (vinyl acetate, n-hexane, 45 °C), remains active after 10 cycles.
Modified GO NPs were added to EP coatings on Zn study their electrochemical, photocatalytic, and morphological properties. The Zn/EP-GO-APTES system showed the best organic pollutant degradation, keeping good corrosion resistance adhesion.
Fatty acid diesters of 2,5-bis-(hydroxymethyl)furan (BHMF), promising candidates as sustainable bioadditives for increasing the cetane number biodiesel fuels, were prepared through a solvent-free Novozym 435-mediated diesterification BHMF with fatty mixture (FAM) resulting from hydrolysis commercial sunflower oil. Under conditions and 15 mbar vacuum, high conversions into obtained in heterogeneous reaction, after gradual solubilization BHMF. After optimization studies (temperature, reaction...
Diabetic retinopathy (DR) and cataracts (CA) have an early onset in diabetes mellitus (DM) due to the redox imbalance inflammation triggered by hyperglycaemia. Plant-based therapies are characterised low tissue bioavailability. The study aimed investigate effect of gold nanoparticles phytoreduced with Rutin (AuNPsR), as a possible solution. Insulin, Rutin, AuNPsR were administered early, six-week rat model DR CA. Oxidative stress (MDA, CAT, SOD) was assessed serum eye homogenates,...
Several functionalized carbon nanotubes have been designed and tested for the purpose of nucleic acid delivery. In this study, capacity SWNTC-COOH siRNA deliverey were investigated delivery in parallel with an efficient commercial system. Hep2G cells reverse-transfected 50 nM (p53 siRNA, TNF-alphasiRNA, VEGFsiRNA) using siPORT NeoFX (Ambion) transfection agent paralel SWNTC-COOH, functionalised siRNA. The highest level gene inhibition was observed cases treated p53 gene; case siPort, value...
A novel phenylalanine ammonia-lyase of the psychrophilic yeast Pseudozyma antarctica (PzaPAL) was identified by screening microbial genomes against known PAL sequences. PzaPAL has a significantly different substrate binding pocket with an extended loop (26 aa long) connected to aromatic ring region active site as compared PALs from eukaryotes. The general properties recombinant expressed in E. coli were characterized including kinetic features this l-phenylalanine (S)-1a and further racemic...
The focus of this study was the preparation sol–gel titanium dioxide (TiO2) coatings, by dip-coating technique, on Ti6Al4V (TiGr5) and specific Ti implant substrates. In order to confer antibacterial properties layers, Eugenol introduced in coatings two separate ways: firstly introducing sol (Eug–TiO2), secondly impregnating into already deposed TiO2 coating (TiO2/Eug). Optimization concentration as well long term were performed orderboth short- long-term investigate prepared samples...
In practice, metal structures are frequently transported or stored before being used. Even in such circumstances, the corrosion process caused by environmental factors (moisture, salty air, etc.) can occur quite easily. To avoid this, surfaces be protected with temporary coatings. The objective of this research was to develop coatings that exhibit effective protective characteristics while also allowing for easy removal, if required. Novel, chitosan/epoxy double layers were prepared on zinc...
Non-covalently iron-porphyrin functionalized N-doped graphene shows a higher peroxidase-like activity than its building blocks alone.
A new and efficient immobilized form of phenylalanine ammonia-lyase (PAL) was obtained by covalent linkage onto amino functionalized single-walled carbon nanotubes (SwCNTNH2) as carrier. The catalytic properties the resulted nanostructured biocatalyst (SwCNTNH2-PAL) were tested in kinetic resolution racemic 2-amino-3-(thiophen-2-yl)propanoic acid 1 ammonia elimination enantiotope selective addition (E)-3-(thiophen-2-yl)acrylic 2. SwCNTNH2-PAL a durable batch mode for from (>85% original...