A5073870397- Cannabis and Cannabinoid Research
- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Palliative Care and End-of-Life Issues
- Homelessness and Social Issues
- Prenatal Substance Exposure Effects
- Bipolar Disorder and Treatment
- Cancer-related cognitive impairment studies
- Patient-Provider Communication in Healthcare
- Religion, Spirituality, and Psychology
- Psychosomatic Disorders and Their Treatments
- Family Support in Illness
- Psychedelics and Drug Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Brain Metastases and Treatment
- Mental Health and Psychiatry
- Cancer Treatment and Pharmacology
- Sleep and related disorders
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Dementia and Cognitive Impairment Research
- Glioma Diagnosis and Treatment
- Poisoning and overdose treatments
- Advanced Radiotherapy Techniques
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Dana-Farber Cancer Institute
2016-2025
Harvard University
2015-2024
Brigham and Women's Hospital
2007-2024
McLean Hospital
2023
Fenway Health
2022
University of Colorado Denver
2020
Dana-Farber Brigham Cancer Center
2018
München Klinik
2018
Suzuki (Japan)
2018
Cancer Institute (WIA)
2018
Background Although almost every state medical marijuana (MM) law identifies cancer as a qualifying condition, little research supports MM's use in oncology. We hypothesized that the discrepancy between these laws and scientific evidence base poses clinical challenges for oncologists. Oncologists' beliefs, knowledge, practices regarding MM were examined this study. Methods In November 2016, we mailed survey on to nationally-representative, random sample of 400 Main outcome measures included...
Object. After conventional doses of 55 to 65 Gy fractionated irradiation, glioblastoma multiforme (GBM) usually recurs at its original location. This institutional phase II study was designed assess whether dose escalation 90 cobalt gray equivalent (CGE) with conformal protons and photons in accelerated fractionation would improve local tumor control patient survival. Methods. Twenty-three patients were enrolled this study. Eligibility criteria included age between 18 70 years, Karnofsky...
In cognitively impaired patients without dementia, the utility of apolipoprotein E (APOE) genotyping is unclear.To evaluate predictive APOE epsilon4 genotype for conversion to probable Alzheimer disease (AD).Naturalistic, longitudinal study.Memory disorders outpatient clinic.A total 136 with memory complaints were determined have mild cognitive impairment and evaluated every 6 months. Fifty-seven age- sex-matched healthy controls annually.Primary outcome measures included AD. Secondary...
Although medical marijuana (MM) may have utility in the supportive care of children with serious illness, it remains controversial. We investigated interdisciplinary provider perspectives on legal MM use cancer.
Background Little is known about medical cannabis (MC)–related care for patients with cancer using MC. Methods Semistructured telephone interviews were conducted in a convenience sample of individuals (n = 24) physician‐confirmed oncologic diagnoses and state/district authorization to use MC (Arizona, California, Florida, Illinois, Massachusetts, Oregon, New York, Washington, DC) from April 2017 March 2019. Standard qualitative techniques used assess the degree MC‐related health oversight,...
We estimated the prevalence of past 30-day cannabis use, evaluated reasons for and identified individual-level factors associated with use among cancer survivors before (2019) during (2020 2021) COVID-19 pandemic. Cancer survivors, aged 18 years older, were from 2019 (n = 8185), 2020 11 084), 2021 12 248) Behavioral Risk Factor Surveillance System. Prevalence held steady through pandemic (8.7%, 7.4%, 8.4% in 2019, 2021, respectively). Of those who used cannabis, 48.7% it medical 54.5% 2020,...
Background: Oncology providers often lack the confidence to make clinical recommendations about medical cannabis (MC). This study aimed develop and evaluate feasibility of implementing an educational curriculum on use MC in patient care for oncology trainees. Methods: A multidisciplinary team designed oncology. The was piloted as a 1-hour interactive webinar across 8 United States–based hematology/oncology fellowship programs between 2022 2023. Incentivized surveys measuring outcomes,...
Abstract Objectives Adequate symptom and quality‐of‐life (SQL) management is a priority during cancer treatment. eHealth timely way to enhance patient‐engagement, facilitate communication, improve health outcomes. The objectives of this study were describe patient caregivers' perspectives for providing, processing, managing SQL data communication identify desired components decision support. Methods Data collected from 64 participants through questionnaires focus groups. Analysis was...
Management of uncontrolled symptoms is an important component quality cancer care. Clinical guidelines are available for optimal symptom management, but not often integrated into the front lines The use clinical decision support (CDS) at point-of-care innovative way to incorporate guideline-based management routine care.The objective this study was develop and evaluate a rule-based CDS system enable multiple in lung patients point-of-care.This conducted three phases involving formative...
Background: Recent and preprohibition studies show that patients with serious illness might benefit from psychedelic-assisted therapies for a range of symptoms, physical, psychosocial, existential. Objective: To explore the potential roles research priorities these in illness. Design, Setting, Participants: Qualitative study based on semistructured interviews 17 experts care and/or psychedelic United States Canada. Measurements: The interview guide elicited participants' perspectives (1)...
Background: With support from the Radcliffe Institute for Advanced Study at Harvard University, we convened researchers representing palliative care, psychosocial oncology, spiritual and psychedelic-assisted therapies. We aimed to define priorities envision an agenda future research on therapies in patients with serious illness. Over two days January 2020, participants engaged iterative series of reflective exercises that elicited their attitude perspectives scientific opportunities this...
Abstract Background Although the vast majority of medical cannabis laws in USA includes cancer as a qualifying condition and cannabis-related stigma influences decision-making regarding botanical, few studies have explored phenomenon oncology. Early findings indicated oncologic to be quite widespread. Methods Semi-structured interviews with 24 adults histories using were analyzed Health Stigma Discrimination Framework. Results Sixteen out participants discussed some depth. The phenomena...
1 Background: Integration of palliative care into oncology is recommended for quality care. Clinicians may benefit from assistance in assessing and managing multiple symptoms. Palliative clinicians have the expertise but not be available or are consulted early course a patient’s disease. Clinical decision support (CDS) offers an innovative way to deliver symptom management trigger referrals at point-of-care. Methods: Twenty their patients were randomized usual (UC) CDS using assessment...
This paper describes the development of an institution-specific website designed to meet supportive and emotional needs young adults (18–39 years old) with cancer in United States. The contains information about topics particular interest adults, coping skills education, resources; has social networking capacity. In a survey users, participants reported increased "connectedness" variable impact on feelings sadness, fear, worry. Recommendations are made for fostering peer interactions,...
Expansion of medical marijuana (MM) laws in the United States may offer oncology new therapeutic options. However, scientific evidence for MM remains infancy. This study qualitatively explored professional opinion around role cancer care.Semistructured interviews were administered to a sample individuals with expertise at interface and nationally. Key informant criteria included an oncologic clinical or research background any following: publications, research, lectures on cannabinoids...
@JCO_ASCO guideline on #cannabis in cancer with @JCOOP_ASCO companion Q&A addressing key clinical questions
Importance Early evidence from studies outside of oncology has suggested that cannabidiol (CBD) may have anxiolytic effects without neuropsychiatric risks. An understanding oral CBD in patients with cancer-related anxiety is urgently needed. Objective To determine whether a single 400-mg dose US Food and Drug Administration–approved improves clinical an oncologic population. Design, Setting, Participants This phase II, double-masked, placebo-controlled, randomized trial was performed at the...