M.F. Gursu

ORCID: 0000-0003-3552-7315
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About
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Research Areas
  • Paraoxonase enzyme and polymorphisms
  • Animal Nutrition and Physiology
  • Apelin-related biomedical research
  • Antioxidant Activity and Oxidative Stress
  • Folate and B Vitamins Research
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Lipid metabolism and disorders
  • Trace Elements in Health
  • Pregnancy-related medical research
  • Circadian rhythm and melatonin
  • Diet and metabolism studies
  • Meat and Animal Product Quality
  • Biochemical Acid Research Studies
  • Bone and Joint Diseases
  • Adipose Tissue and Metabolism
  • Cardiovascular Disease and Adiposity
  • Hibiscus Plant Research Studies
  • Chromium effects and bioremediation
  • Birth, Development, and Health
  • Pharmacological Effects and Toxicity Studies
  • Pregnancy and preeclampsia studies
  • Effects of Radiation Exposure
  • Adipokines, Inflammation, and Metabolic Diseases
  • Fatty Acid Research and Health
  • Sulfur Compounds in Biology

Fırat University
2007-2024

Haseki Eğitim ve Araştırma Hastanesi
2010

Elazığ Eğitim ve Araştırma Hastanesi
2002

Two sources of zinc [ZnSO4.H2O or ZnPicolinate (ZnPic)] supplementation were evaluated for their effects on performance, carcass weight, levels malondialdehyde, and vitamins C, E, A in Japanese quail (Coturnix coturnix Japonica) exposed to high ambient temperature 34 degrees C. The birds (n = 360; 10-d-old) randomly assigned 12 treatment groups consisting 3 replicates 10 each a 2 × factorial arrangement treatments (temperatures, sources, levels). Birds kept wire cages temperature-controlled...

10.1093/ps/84.6.882 article EN cc-by-nc-nd Poultry Science 2005-06-01

Lung cancer (LC) is the leading cause of cancer-related deaths. Oxidative DNA damage may contribute to risk. The antioxidant paraoxonase (PON1) an endogenous free radical scavenger in human body. aim this study was determine serum PON1 and arylesterase (ARE) activities patients with newly diagnosed LC. This case control involved a total 39 LC (untreated) same number age- sex-matched healthy individuals. Serum ARE addition lipid parameters were measured both groups. found be lower compared...

10.1186/1471-2407-7-48 article EN cc-by BMC Cancer 2007-03-15

The aim of this study was to investigate the effects 1,25-dihydroxyvitamin-D3 (vitamin D) and omega-3 polyunsaturated fatty acids (omega-3 PUFA) on experimentally induced endometriosis in a rat model. A prospective, single-blind, randomized, controlled experimental performed 30 Wistar female rats. Endometriosis surgically by implanting endometrial tissue abdominal peritoneum. Four weeks later, second laparotomy assess pre-treatment implant volumes cytokine levels. rats were randomized into...

10.1016/j.tjog.2015.06.018 article EN cc-by-nc-nd Taiwanese Journal of Obstetrics and Gynecology 2016-12-01

1. The effects of chromium picolinate and biotin supplementation alone in combination on performance, carcase characteristics, malondialdehyde (MDA), vitamin C, E, glucose cholesterol levels were evaluated Japanese quail exposed to high ambient temperature.

10.1080/00071660500190918 article EN British Poultry Science 2005-08-01

Skeletal abnormalities, low bone mass, deformities, and fractures increase the risk of osteoporosis osteoarthritis, which are concern from both a public standpoint cost-of-care burden standpoint. Arginine silicate inositol complex (ASI; Arg = 49.47%, silicone 8.2%, 25%) is novel, bioavailable source Si one that offers potential benefits for vascular health. abnormalities architectural deterioration tissue common under hot climate conditions in poultry industry. In this study, we evaluated...

10.1093/ps/85.3.486 article EN cc-by-nc-nd Poultry Science 2006-03-01

An experiment utilizing Cobb-500 male broilers was conducted to evaluate the effects of vitamin E (d1--to- copheryl acetate) supplementation at various concentrations (0, 62.5, 125, 250, or 500 mg/kg diet) on performance and serum Triiodothyronine (T3), Thyroxin (T4), Adrenocorticotropine Hormone (ACTH), some metabolites minerals in reared under heat stress (32°C). One day-old 150 were randomly assigned 5 treatment groups, 3 replicates 10 birds each. The received either a basal diet...

10.17221/5813-vetmed article EN cc-by-nc Veterinární Medicína 2002-04-30

This experiment was conducted to evaluate the effects of vitamin C (L-ascorbic acid) and E (?-tocopherol acetate) on egg production, quality, lipid peroxidation status (measured as MDA), some serum metabolites in laying hens (Hy-Line) maintained at a low ambient temperature (6°C). One hundred twenty (18-wk-old) were divided into four groups, 30 per group. The fed either basal diet or supplemented with 250 mg L-ascorbic acid/kg diet, ?-tocopherol acetate/kg acid plus diet. Although feed...

10.17221/5747-vetmed article EN cc-by-nc Veterinární Medicína 2003-01-31

1. The effects of ascorbic acid (l-ascorbic acid) and melatonin supplementation on performance, carcase characteristics, malondialdehyde (MDA) as lipid peroxidation indicator, acid, retinol, tocopherol mineral status in the Japanese quail (Coturnix coturnix japonica) exposed to high ambient temperature were evaluated. 2. Two hundred forty quails (10 d old) randomly assigned 8 treatment groups consisting 10 replicates three birds each. kept a temperature-controlled room at 22°C...

10.1080/00071660410001668941 article EN British Poultry Science 2004-02-01

Background: Oxidative stress is believed to be an important factor in the pathogenesis of acute lung injury (ALI). Aims:The aim this study was investigate possible protective role alpha-lipoic acid (α-LA) on oleic (OA)-induced ALI rats. Study Design: Animal experiment.Methods: A total thirty-five rats were divided into five groups study.Group 1 served as a control group.Rats Group 2 administered α-LA intraperitoneally at dose 100 mg/kg body weight (BW).Rats 3 (OA) OA intravenously BW.In 4...

10.5152/balkanmedj.2013.8426 article EN Balkan Medical Journal 2013-09-10

Investigation of the effects prostaglandin E1, melatonin, and oxytetracycline on lipid peroxidation, antioxidant paraoxonase activities, homocysteine levels in an experimental model spinal cord injury.To determine efficacy whether can be used as monitoring parameters acute oxidative stress injury.Melatonin has been found useful injury previous studies. No study exists investigating well response type enzyme injury.Sixty-three male albino Wistar rats were anesthetized with 400 mg/kg chloral...

10.1097/01.brs.0000083163.03910.b1 article EN Spine 2003-08-01

Leiomyomas (fibroids) are benign tumors of the uterus affecting millions women. Spontaneous leiomyomas oviduct common Japanese quail (Coturnix coturnix japonica), which makes it a good animal model for screening potential agents testing in prevention and treatment human myoma uteri. Because dietary intake lycopene has been associated with reduced risk variety cancers, we investigated effects supplementation on development quail. We also measured serum levels oxidative stress markers...

10.1207/s15327914nc5002_8 article EN Nutrition and Cancer 2004-11-01

We have investigated the effects of surgical menopause and estrogen replacement therapy (ERT) on serum paraoxonase 1 (PON1) activity plasma malondialdehyde (MDA) levels in surgically postmenopausal women.Thirty-six healthy perimenopausal women who underwent total abdominal hysterectomy bilateral salpingo-oopherectomy for uterine myoma were enrolled this study. Blood samples taken from subjects day before surgery, starting ERT (30 days after operation) 30th start therapy.After menopause,...

10.1159/000082647 article EN Gynecologic and Obstetric Investigation 2004-12-14
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