A5039014629- Neuroscience and Neural Engineering
- Mechanical Circulatory Support Devices
- Wireless Body Area Networks
- Planarian Biology and Electrostimulation
- Viral Infections and Immunology Research
- Receptor Mechanisms and Signaling
- Tissue Engineering and Regenerative Medicine
- Monoclonal and Polyclonal Antibodies Research
- Cardiovascular Function and Risk Factors
- Muscle activation and electromyography studies
- Animal health and immunology
- Cardiac pacing and defibrillation studies
- Respiratory Support and Mechanisms
- Cardiac Structural Anomalies and Repair
- Cardiac Ischemia and Reperfusion
- Advanced Sensor and Energy Harvesting Materials
- Cardiomyopathy and Myosin Studies
- Platelet Disorders and Treatments
- Microfluidic and Capillary Electrophoresis Applications
- Congenital Heart Disease Studies
- Blood groups and transfusion
- Electromagnetic Fields and Biological Effects
- Celiac Disease Research and Management
- Wireless Power Transfer Systems
- Inflammatory Myopathies and Dermatomyositis
Berlin Heart (Germany)
2002-2023
Institute for Cardiovascular Diseases of Vojvodina
2020
Abstract Aims Beyond the influence of stimulating devices on cardiac excitation, their use in treating patients with heart failure has positive effects myocardium at molecular level. Electrical signals can induce a wide spectrum living tissue. Therefore, we sought to determine whether applying electrical microcurrent directly failing hearts leads functional improvement. Methods and results Sixteen male spontaneously hypertensive rats (SHRs) underwent application patch electrode left...
Abstract Aims Most devices for treating ambulatory Class II and III heart failure are linked to electrical pulses. However, a steady electric potential gradient is also necessary appropriate myocardial performance may be disturbed by structural diseases. We investigated whether chronic application of microcurrent the feasible safe improves cardiac performance. The results this study should provide guidance design two‐arm, randomized, controlled Phase trial. Methods This single‐arm,...
Background: 80 percent of patients with non-ischemic heart failure (HF) and reduced ejection fraction have autoantibodies against β1- adrenoceptors (β1-AAB), which cause and/or sustain HF. The removal β1-AAB by immunoadsorption (IA) leads to an improvement cardiac function significantly mortality. With the aptamer BC 007, a new drug is under study that neutralizes G-Protein-coupled receptors (GP-AAB) including β1-AAB. Aptamers are often referred as chemical antibodies offer number advantages...
An axial-flow pump as an assist device with magnetic bearings was developed the following characteristics: Power consumption at 8,600 rpm and S L/min flow 100 mmHg pressure is 8.5 W. Flow may be increased up to 7 against 150 mmHg. Weight 200 g diameter 30 mm. For levitation of impeller equipped radially passive axially active bearings. Magnetic additional forces act on rotor in axial direction. A sensor a controlling unit are required keep optimal position minimal energy input. Therefore,...
The INCOR I ventricular assist device is an axial-flow pump with magnetically levitated hearings and low power consumption. It capable of pumping 5 liters against 100 mmHg at a rotational speed 8,600 rpm. VAD was evaluated in 14 calves to test hemolysis thrombogenicity short-and long-term observation. Five died within 12 hours postop. due persistent ductus Botalli which not anticipated therefore overlooked. One slip-off cannula inadequately connected. Six were euthanized after 40 days (d)...