A5076965576- RNA Interference and Gene Delivery
- Advanced Drug Delivery Systems
- Nanoparticle-Based Drug Delivery
- Drug Solubulity and Delivery Systems
- Advancements in Transdermal Drug Delivery
- Cystic Fibrosis Research Advances
- Lipid Membrane Structure and Behavior
- Virus-based gene therapy research
- Hydrogels: synthesis, properties, applications
- Analytical Chemistry and Chromatography
- Protein Interaction Studies and Fluorescence Analysis
- CRISPR and Genetic Engineering
- Seaweed-derived Bioactive Compounds
- Photodynamic Therapy Research Studies
- Cancer Research and Treatment
- Pharmacological Effects of Natural Compounds
- Analytical Methods in Pharmaceuticals
- Wound Healing and Treatments
- Protein Hydrolysis and Bioactive Peptides
- Inhalation and Respiratory Drug Delivery
- Synthesis of Organic Compounds
- Cellular transport and secretion
- Nerve injury and regeneration
- Echinoderm biology and ecology
- Plant chemical constituents analysis
JSS Academy of Higher Education and Research
2021-2024
GITAM University
2018-2020
Formulation Development and Evaluation of Paclitaxel Loaded Solid Lipid Nanoparticles Using Glyceryl MonostearateA. Dinda, I. Biswal, P. Chowdhury, R. Mohapatra
Neurologic disorders currently affect approximately 100 million people worldwide. most often occur due to inherent genetic mutations, which lead numerous types of functional disruptions in nervous system development. disease-related events, such as and epigenetic changes, cause inflammatory processes the area may enhance disease cycle. Gene therapy has progressed a compelling therapeutic approach for various neurodegenerative disorders. Several efforts gene rely on discovering novel vectors,...
The effective treatment of central nervous system (CNS) disorders such as multiple sclerosis (MS) has been challenging due to the limited ability therapeutic agents cross blood-brain barrier (BBB). In this study, we investigated potential nanocarrier systems deliver miR-155-antagomir-teriflunomide (TEF) dual therapy brain via intranasal (IN) administration manage MS-associated neurodegeneration and demyelination. Our results showed that combinatorial miR-155-antagomir TEF loaded in...
Injectable, in situ-forming hydrogels, both biocompatible and biodegradable, have garnered significant attention tissue engineering due to their potential for creating adaptable scaffolds. The adaptability of these made from natural proteins polysaccharides, opens up a world possibilities. In this study, sodium alginate was used synthesize di-aldehyde (ADA) through periodate oxidation, resulting lower molecular weight reduced viscosity, with different degrees oxidation (54% 70%)....
Objective: The main motive is to develop proniosomes loaded orabase for enhanced permeation and prolonged release of aceclofenac oro dental conditions.Methods: Various (ACL) proniosomal gels were formulated employing various surfactants, span 60 was superior significant loading into orabase. formulations scrutinized entrapment efficiency, optical microscopy, in vitro diffusion studies, mucoadhesive strength, ex-vivo studies drug-excipient interactions determined by FTIR spectroscopy.Results:...
An existence of transdermal delivery tool, proniosomal gel, has established to showed remarkable development for lipophilic/hydrophilic drugs over additional formulations. Newer lipophilic nature emerge poor bioavailability, irregular absorption, and pharmacokinetic changes. Therefore, this novel drug system been proved advantageous other oral topical candidates bypass such disruption. This gel basically is a compact semi-solid liquid crystalline (gel) composed non-ionic surfactants easily...
Objective: The present study involves the development of SNEDDS employing essential oils for enhancing biopharmaceutical performance.
 Methods: Preliminary investigations suggested selection cinnamon oil as an oil, tween 60 a surfactant, while transcutol HP cosolvent formulating SNEDDS. Formulations evaluated stability, robustness to dilution, and emulsification time, droplet size, zeta potential (ζ), cloud point, in vitro drug release, excipient compatibility, TEM, stability assessment...
Objective: To develop and formulate doxycycline hydrochloride hydrogels employing various polymers for wound healing application.
 Methods: A thermo-reversible gel can transmute from a sol-gel in replication to environmental temperature vicissitudes made up of gallic acid (GA) tamarind seed polysaccharide (TSP). An antimicrobial agent (doxycycline hydrochloride) integrated provide the benefit efficiently safeguard infection. low causes TSP aggregate intermolecularly with GA create...
Objective: The study aims for the design and evaluation of floating tablets emtricitabine (EMT), post oral administration to sustain release enhance gastric residence time (GRT).
 Methods: EMT is a nucleoside reverse-transcriptase inhibitor prevention treatment human immunodeficiency virus (HIV) infection. investigation was considered formulate tablet with various agents. formulation included concentrations hydroxypropyl methylcellulose (HPMC) k4m, ethylcellulose, microcrystalline...
An existence of transdermal delivery tool, proniosomal gel, has established to showed remarkable development for lipophilic/hydrophilic drugs over additional formulations. Newer lipophilic nature emerge poor bioavailability, irregular absorption, and pharmacokinetic changes. Therefore, this novel drug system been proved advantageous other oral topical candidates bypass such disruption. This gel basically is a compact semi-solid liquid crystalline (gel) composed non-ionic surfactants easily...