A5100442290- Bladder and Urothelial Cancer Treatments
- Cancer Immunotherapy and Biomarkers
- Ferroptosis and cancer prognosis
- Cancer-related molecular mechanisms research
- Prostate Cancer Treatment and Research
- Esophageal Cancer Research and Treatment
- Immune cells in cancer
- Helicobacter pylori-related gastroenterology studies
- Cancer, Lipids, and Metabolism
- Galectins and Cancer Biology
- Amoebic Infections and Treatments
- RNA modifications and cancer
- Infectious Diseases and Tuberculosis
- Clostridium difficile and Clostridium perfringens research
- Cytomegalovirus and herpesvirus research
- Spinal Dysraphism and Malformations
- Epigenetics and DNA Methylation
- Viral-associated cancers and disorders
Stanford University
2024
Lawrence Berkeley National Laboratory
2023
Southern University of Science and Technology
2023
China Academy of Chinese Medical Sciences
2023
First Affiliated Hospital of Harbin Medical University
2023
Wuhan University
2023
Kunming Medical University
2023
First Affiliated Hospital of Wenzhou Medical University
2023
Wuhan Institute of Virology
2023
The Affiliated Yongchuan Hospital of Chongqing Medical University
2023
Abstract Background Helicobacter pylori ( H. ) infection of gastric epithelial cells induces inflammatory response. Outer membrane proteins (OMPs), Type 4 secretion system (T4SS) encoded by cag PAI, and the effector protein CagA are involved in pathogenesis . possesses a gene encoding LuxS which synthesizes AI‐2, quorum sensing signal molecule. The aim this study was to investigate role AI‐2 expression virulence factors response (AGS) induced Materials Methods Δ luxS mutant constructed,...
Background: The tumor suppressor gene TP53 is frequently mutated or inactivated in bladder cancer (BLCA), which implicated the pathogenesis of tumor. However, cellular mechanisms mutations are complicated, yet well-defined, but their clinical prognostic value management BLCA remains controversial. This study aimed to explore role mutation regulating microenvironment (TME), elucidate effects activity on prognosis and immunotherapy response. Methods: A TP53-related signature based TP53-induced...
Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease with varying clinical courses and responses to treatment. To improve the prognosis of patients, it necessary understand such heterogeneity.
Muscle invasive bladder cancer (MIBC) is a malignancy with considerable heterogeneity. The MIBC tumor microenvironment (TME) highly complex, comprising diverse phenotypes and spatial architectures. complexity of the TME must be characterized to provide potential targets for precision therapy. Herein, an integrated combination mass cytometry imaging was used analyze cells, immune characteristics 44 patients. We detected cell clusters abnormal phenotypes. In particular, we identified...
Muscle invasive bladder cancer (MIBC) is a heterogeneous disease with high recurrence rate and poor clinical outcomes. Molecular subtype provides new framework for the study of MIBC heterogeneity. Clinically, can be classified as basal luminal subtypes; they display different pathological characteristics, but molecular mechanism still unclear. Lipidomic metabolomic molecules have recently been considered to play an important role in genesis development tumors, especially potential...
Hepatocellular carcinoma (HCC) is a disease with great heterogeneity and high mortality rate. It crucial to identify reliable biomarkers for diagnosis, prognosis, treatment improve clinical outcomes in patients HCC. Alpha-fetoprotein (AFP) not only widely used biomarker practice but also plays complicated role HCC, it has recently been considered be related immunotherapy. MicroRNAs (miRNAs) are regarded as key regulators promising of We investigated the an AFP-related miRNA, miR-135b-5p, HCC...