A5091748693- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Click Chemistry and Applications
- Cancer therapeutics and mechanisms
- Synthesis of Tetrazole Derivatives
- Quinazolinone synthesis and applications
- Synthesis and Characterization of Heterocyclic Compounds
Aeronautical Development Agency
2023-2024
GITAM University
2023-2024
Abstract A very interesting foundation for this study is the creation of new methods modifying compounds with a 1,2,3‐triazole and chalcone scaffolds, as these are significant in organic synthesis, particularly synthesis bioactive compounds. To contribute to development an efficient method conversion antimicrobial antituberculosis heterocyclics, novel series cyclohepta pyridinone fused 1,2,3‐triazolyl chalcones were designed synthesized. All newly prepared scaffolds characterized by FT‐IR,...
Our current work is aimed at synthesizing novel substituted 1,2,4-triazolyl-fluoroquinolone analogs and study of their biological activity to find active promising molecules. The structural elucidation the products was demonstrated by a variety spectroscopic methods such as IR, 1 H-NMR, 13 C-NMR, mass elemental analysis. newly synthesized 1,2,4-triazole derivatives were tested in vitro for ability inhibit growth seven different microbes including S. epidermidis, pneumoniae, aureus, B....
Abstract: The synthesis and biological properties of molecules simultaneously comprising various heterocycles, such as fused 2-quinolones 1,2,3-triazoles, have been evaluated a part our ongoing research in medicinal organic chemistry. We were successful developing synthetic procedure for 1,2,3-triazole substituted quinolone derivatives. Infrared, proton, carbon nuclear magnetic resonance, mass spectroscopy elemental analysis used to characterise the structures recently synthesised triazole...