A5059936198- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Neurological disorders and treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Advanced MRI Techniques and Applications
- Cardiac Imaging and Diagnostics
- Cardiomyopathy and Myosin Studies
- COVID-19 diagnosis using AI
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Structural Anomalies and Repair
- Muscle Physiology and Disorders
- Cardiac Valve Diseases and Treatments
- Ultrasound in Clinical Applications
- Acute Myocardial Infarction Research
- Lung Cancer Diagnosis and Treatment
- Congenital Heart Disease Studies
- Artificial Intelligence in Healthcare and Education
- Pulmonary Hypertension Research and Treatments
- Radiation Dose and Imaging
Radboud University Nijmegen
2020-2024
Radboud University Medical Center
2020-2024
Rijnstate Hospital
2023-2024
University Medical Center
2018-2023
University Medical Center Utrecht
2014-2021
Heidelberg University
2015-2021
University Hospital Heidelberg
2015-2021
Utrecht University
2021
Maastricht School of Management
2020
Medisch Centrum Haaglanden
2020
Background A categorical CT assessment scheme for suspicion of pulmonary involvement coronavirus disease 2019 (COVID-19 provides a basis gathering scientific evidence and improved communication with referring physicians. Purpose To introduce the COVID-19 Reporting Data System (CO-RADS) use in standardized on unenhanced chest images to report its initial interobserver agreement performance. Materials Methods The Dutch Radiological Society developed CO-RADS based other efforts standardization,...
Background The coronavirus disease 2019 (COVID-19) pandemic has spread across the globe with alarming speed, morbidity, and mortality. Immediate triage of patients chest infections suspected to be caused by COVID-19 using CT may assistance when results from definitive viral testing are delayed. Purpose To develop validate an artificial intelligence (AI) system score likelihood extent pulmonary on scans Reporting Data System (CO-RADS) severity scoring systems. Materials Methods CO-RADS AI...
Parameters using myocardial strain analysis may predict response to cardiac resynchronization therapy (CRT). As the agreement between currently available imaging modalities is unknown, three different were compared. Twenty-seven CRT-candidates, prospectively included in MARC study, underwent magnetic resonance (CMR) and echocardiographic examination. Left ventricular (LV) circumferential was analysed with CMR tagging (CMR-TAG), feature tracking (CMR-FT), speckle echocardiography (STE). Basic...
Various strain parameters and multiple imaging techniques are presently available including cardiovascular magnetic resonance (CMR) tagging (CMR-TAG), CMR feature tracking (CMR-FT), speckle echocardiography (STE). This study aims to compare predictive performance of different evaluate results per technique predict cardiac resynchronization therapy (CRT) response.Twenty-seven patients were prospectively enrolled underwent echocardiographic examination before CRT implantation. Strain analysis...
Background: Previous studies indicated the importance of intrinsic left ventricular (LV) electric delay (QLV) for optimal benefit to cardiac resynchronization therapy. We investigated use QLV achieving acute hemodynamic response therapy with a quadripolar LV lead. Methods and Results: Forty-eight heart failure patients bundle branch block were prospectively enrolled (31 men; age, 66±10 years; ejection fraction, 28±8%; QRS duration, 176±14 ms). Immediately after implantation, invasive...
Current optimization of atrioventricular (AV) and interventricular (VV) intervals in cardiac resynchronization therapy (CRT) is time consuming subject to noise. We aimed prove the principle that best hemodynamic effect CRT achieved by cancelation opposing electrical forces, detectable from QRS morphology 3D vectorcardiogram (VCG). Different degrees left (LV) right ventricular (RV) pre-excitation were induced, using variation AV during LV pacing 20 patients with bundle branch block (LBBB) VV...
Echocardiography is used in cardiac resynchronisation therapy (CRT) to assess function, and particular left ventricular (LV) volumetric status, prediction of response. Despite its widespread applicability, LV volumes determined by echocardiography have inherent measurement errors, interobserver intraobserver variability, discrepancies with the gold standard magnetic resonance imaging. Echocardiographic predictors CRT response are based on mechanical dyssynchrony. However, parameters mainly...
Although mechanical dyssynchrony parameters derived by speckle tracking echocardiography (STE) may predict response to cardiac resynchronization therapy (CRT), comparability of with different STE vendors is unknown. In the MARC study, echocardiographic images heart failure patients obtained before CRT implantation were prospectively analysed vendor specific software (GE EchoPac and Philips QLAB) vendor-independent (TomTec 2DCPA). Response was defined as change in left ventricular (LV)...
This study was performed to evaluate the feasibility of intra-procedural visualization optimal pacing sites and image-guided left ventricular (LV) lead placement in cardiac resynchronization therapy (CRT). In fifteen patients (10 males, 68 ± 11 years, 7 with ischemic cardiomyopathy ejection fraction 26 5%), were identified pre-procedurally using imaging. Cardiac magnetic resonance (CMR) derived scar dyssynchrony maps created for all patients. six anatomy phrenic nerve (LPN) coronary sinus...
Change in left ventricular end-systolic volume (∆LVESV) is the most frequently used surrogate marker measuring response to cardiac resynchronisation therapy (CRT). We investigated whether ∆LVESV best measure discriminate between a favourable and unfavourable outcome this equally applicable non-ischaemic ischaemic cardiomyopathy. 205 CRT patients (age 65 ± 12 years, 69 % men) were included. At baseline 6 months echocardiographic studies, exercise testing laboratory measurements performed. was...
Left ventricular (LV) strain and rotation are emerging functional markers for early detection of LV dysfunction have been associated with the burden myocardial fibrosis in several disease states. This study examined association between deformation (i.e., rotation) extent location pediatric patients Duchenne muscular dystrophy (DMD).34 DMD underwent cardiovascular magnetic resonance (CMR) late gadolinium enhancement (LGE) to assess fibrosis. Offline CMR feature-tracking analysis was used...
Stress echocardiography (SE) has recently regained momentum as an important diagnostic tool for the assessment of both ischemic and non-ischemic heart disease. Performing SE during physical exercise is challenging due to a suboptimal patient position vigorous movements patient's chest. This hampers stable ultrasound reduces performance SE. A probe would facilitate producing high quality images continuous measurements. With Probefix (Usono, Eindhoven, The Netherlands), newly developed fixate...
Response to cardiac resynchronization therapy (CRT) is often assessed six months after implantation. Our objective was assess the number of patients changing from responder non-responder between and 14 months, so-called late non-responders, compare them who were both at stable responders. Furthermore, we predictive values 14-month response concerning clinical outcome.105 eligible for CRT enrolled. Clinical, laboratory, ECG, echocardiographic parameters patient-reported health status (Kansas...
Dynamic myocardial computed tomography perfusion (CTP) is a novel imaging technique that increases the applicability of CT for cardiac imaging; however, scanning requires substantial radiation dose.
This study aims to define an atrioventricular (AV) delay optimization method for cardiac resynchronization therapy (CRT) with a quadripolar left ventricular (LV) lead based on intrinsic conduction intervals.Heart failure patients bundle branch block underwent CRT implantation LV lead. Invasive pressure-volume loops were recorded during four biventricular and three multi-point pacing (MPP) settings, using patient-specific paced AV delays. Haemodynamic response was defined as change in stroke...
Abstract Introduction The changes in ventricular repolarization after cardiac resynchronization therapy (CRT) are poorly understood. This knowledge gap is addressed using a multimodality approach including electrocardiographic and echocardiographic measurements patients patient‐specific computational modeling. Methods In 33 were performed before at various intervals CRT, both during CRT‐ON temporary CRT‐OFF. T‐wave area was calculated from vectorcardiograms, reconstructed the 12‐lead...
With the trend towards childhood surgery in patients with Ebstein anomaly (EA), thorough imaging is crucial for patient selection. This study aimed to assess biventricular function by echocardiography and cardiac magnetic resonance (CMR) compare EA severity classifications. Twenty-three (8-17 years) underwent CMR. Echocardiographic parameters included tricuspid annular plane systolic excursions (TAPSE), fractional area change of functional right ventricle (fRV-FAC), fRV free wall peak...