About
Contact & Profiles
A5086887930
Research Areas
- Cardiovascular Disease and Adiposity
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
University of Minnesota
2023
Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome, but predominant subset of HFpEF patients has metabolic syndrome (MetS). Mechanistically, systemic, nonresolving inflammation associated MetS might drive remodeling. Free fatty acid receptor 4 (Ffar4) GPCR for long-chain acids that attenuates dysfunction and resolves inflammation. Therefore, we hypothesized Ffar4 would attenuate remodeling in secondary to (HFpEF-MetS). To test this hypothesis, mice systemic...
10.1016/j.jlr.2023.100374
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Journal of Lipid Research
2023-04-17
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