A5053147591- Schizophrenia research and treatment
- Mental Health Research Topics
- Child and Adolescent Psychosocial and Emotional Development
- Personality Disorders and Psychopathology
- Diet and metabolism studies
- Treatment of Major Depression
- Eating Disorders and Behaviors
- Death Anxiety and Social Exclusion
- Child Abuse and Trauma
- Mental Health Treatment and Access
- Maternal Mental Health During Pregnancy and Postpartum
- Suicide and Self-Harm Studies
- Grief, Bereavement, and Mental Health
- Mental Health and Psychiatry
- Psychiatric care and mental health services
- Digital Mental Health Interventions
- Tryptophan and brain disorders
- Psychotherapy Techniques and Applications
- Bipolar Disorder and Treatment
- Attachment and Relationship Dynamics
- Paranormal Experiences and Beliefs
- Health disparities and outcomes
- Pharmacology and Obesity Treatment
- Posttraumatic Stress Disorder Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
LMU Klinikum
2017-2024
Ludwig-Maximilians-Universität München
2017-2024
Heidelberg University
2023
German Center for Diabetes Research
2023
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2016-2021
München Klinik
2017
Background: Interpersonal difficulties are a key feature of persistent depressive disorder (PDD) and borderline personality (BPD). Caught in vicious circle dysfunctional interpersonal transaction, PDD BPD patients at great risk experiencing prolonged loneliness. Loneliness, turn, has been associated with the development mental disorders chronic illness trajectories. Besides, several factors may contribute to experience loneliness across lifespan, such as social network characteristics,...
Weight gain is a common side effect in psychopharmacology; however, targeted therapeutic interventions and prevention strategies are currently absent day-to-day clinical practice. To promote the development of such strategies, identification factors indicative patients at risk essential. In this study, we developed transdiagnostic model using comparing decision tree classifiers, logistic regression, XGboost, support vector machine to predict weight ≥5% body during first 4 weeks treatment...
Abstract Background Perceived loneliness and objective social network size are related but distinct factors, which negatively affect mental health prevalent in patients who have experienced childhood maltreatment (CM), for example, with persistent depressive disorder (PDD) borderline personality (BPD). This cross-diagnostic study investigated whether loneliness, size, or both associated self-reported CM. Methods Loneliness were assessed a population-based sample at two time points (Study 1,...
Abstract Social rejection and exclusion (ostracism) represent main stressors in daily life even threaten mental physical health. Abundant data from subjective measures social paradigms are available, but the dynamic behavioral response is largely unexplored. Here, we applied modified variants of Cyberball paradigm two consecutive experiments to investigate adaptive emotional reactions partial exclusion. In experiment 1, 68 healthy participants (females, mean age 24.76 ± 4.05 years) played 2...
Die kurzfristige Wirksamkeit von Psycho- und Pharmakotherapie bei Depressionen, ob als Monotherapie oder in Kombination, ist durch viele Studien gut belegt. Weitaus weniger Belege gibt es jedoch für die langfristige ab 1 Jahr nach Akuttherapie dieser Behandlungsformen. Durch eine systematische Suche den Datenbanken Pubmed PsychINFO konnten 13 randomisierte kontrollierte (RCTs; Psychotherapie vs. Kombination Monotherapien) identifiziert werden, denen Follow-up-Ergebnisse vorliegen; der...
Translational research on complex, multifactorial mental health disorders, such as bipolar disorder, major depressive schizophrenia, and substance use disorders requires databases with large-scale, harmonized, integrated real-world data. The Munich Mental Health Biobank (MMHB) is a health-specific biobank that was established in 2019 to collect, store, connect, supply high-quality phenotypic data biosamples from patients study participants, including healthy controls, recruited at the...
Patients with borderline personality disorder (BPD) show interpersonal deficits, and altered emotional oxytocin (OT) responses to social exclusion (Cyberball). In order extend previous findings, this study applies a novel Cyberball variant. Nineteen BPD patients 56 healthy controls (HC) played for 2 minutes of inclusion, 5 partial by one two co-players, total both. Plasma OT levels at baseline after 7, 9, 15, 40 were measured radioimmunoassay. showed greater aversive reaction trend reduction...
Introduction: The Cognitive Behavioral Analysis System of Psychotherapy (CBASP) was developed for the treatment persistent depressive disorder (PDD), where comorbid personality disorders (PD) are common. In contrast to other PD, borderline (BPD) is often regarded as an exclusion criterion CBASP. clinical settings, however, subthreshold BPD symptoms prevalent in PDD and may not be obvious at initial assessment prior therapy. As data on their impact CBASP outcome very limited, this...
Overweight and obesity are health issues that increasing worldwide. Patients with severe mental illness particularly vulnerable for various reasons, including the intake of weight gain-associated drugs. In this pilot study, we targeted eating behavior as a predictor medication-induced gain developed module prevention program ("Eating More Consciously") to be evaluated by psychiatric inpatients. Thirty-three patients participated in behaviorally oriented group therapy 2 modules 120 minutes...
Abstract Many psychiatric patients suffer from overweight/obesity and subsequent metabolic disturbances, where psychotropic medication is one of the main contributors. However, magnitude weight gain ranges individually, which leads to questioning role other contributors like lifestyle factors. The present study investigated several factors among inpatients, their relation biological factors, predictive capability for during treatment. Using a naturalistic observational design, inpatients all...
Borderline personality disorder (BPD) is a mental health condition characterized by an inability to regulate emotions or accurately process the emotional states of others. Previous neuroimaging studies using classical univariate analyses have tied such emotion dysregulation aberrant activity levels in amygdala patients with BPD. However, multivariate not yet been used investigate how representational spaces information may be systematically altered BPD.Patients BPD performed face matching...
A subgroup of patients with Major Depressive Disorder shows signs low-grade inflammation and metabolic abberances, while antidepressants can induce weight gain subsequent disorders, lacking antidepressant response is associated inflammation.A comprehensive investigation patient phenotypes their predictive capability for treatment after psychotropic will be performed. The following factors analyzed: inflammatory markers, gut microbiome composition, lifestyle indicators (eating behavior,...
Adverse childhood experiences (ACE) have been linked to less prosocial behavior during social exclusion in vulnerable groups. However, little is known about the impact of timing ACE and roles protective factors. Therefore, this study investigated association behavioral response experimental partial with adverse adaptive across age groups resilience clinical persistent depressive disorder borderline personality disorder, i.e., high ACE, healthy controls (HC) (N = 140). childhood, youth,...