A5102817399- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Angiogenesis and VEGF in Cancer
- Phytochemicals and Antioxidant Activities
- Traumatic Brain Injury and Neurovascular Disturbances
- Nuts composition and effects
- Metabolomics and Mass Spectrometry Studies
- Circular RNAs in diseases
- Nanoplatforms for cancer theranostics
- Cancer, Lipids, and Metabolism
- Bioactive Natural Diterpenoids Research
- Cancer, Hypoxia, and Metabolism
- RNA and protein synthesis mechanisms
- Potato Plant Research
- RNA Research and Splicing
- Cancer Cells and Metastasis
- Cancer Immunotherapy and Biomarkers
- Medicinal Plants and Neuroprotection
- Natural Antidiabetic Agents Studies
Southwest Medical University
2017-2024
Shanghai Cell Therapy Research Institute
2022-2024
First Affiliated Hospital of Sichuan Medical University
2022-2024
Zhejiang University
2008
Abstract RNA modification, especially N6-methyladenosine, 5-methylcytosine, and N7-methylguanosine methylation, participates in the occurrence progression of cancer through multiple pathways. The function expression these epigenetic regulators have gradually become a hot topic research. Mutation regulation noncoding RNA, lncRNA, play major role cancer. Generally, lncRNAs exert tumor-suppressive or oncogenic functions its dysregulation can promote tumor metastasis. In this review, we...
Lung cancer is a malignant tumor with high incidence in China, especially non-small cell lung (NSCLC), which the main threat to human life, terrible morbidity and mortality. The research on treatment mechanism of NSCLC has been forefront hotspot research. Recent patents show that alpha-solanine (α-solanine) exhibits best anti-cancer activity, although its target related remain be elucidated.This study aims explore possible targets mechanisms α-solanine through network pharmacology...
Neuronal apoptosis plays a critical role in the pathogenesis of Alzheimer's disease (AD). Previous studies have shown that lychee seed saponins (LSS), isolated and extracted from traditional Chinese medicine seeds, possess many beneficial activities including anti-oxidation, anti-diabetes, anti-AD, etc. In present study, we established an vitro neuronal apoptotic model PC12 cells induced by Aβ
Abstract Background Muscle‐invasive bladder cancer (MIBC), a that spreads into the detrusor muscle of bladder, leads to poor outcome. Long noncoding RNA LINC00675 has been reported play import roles in several types, although its biological function and underlying mechanism MIBC remain largely unclear. Methods Eighty‐nine patients with were enrolled present study. expression was measured using quantitative reverse transcription‐polymerase chain reaction. Protein detected western blotting....