- Schizophrenia research and treatment
- Mental Health and Psychiatry
- German Literature and Culture Studies
- Psychiatric care and mental health services
- Mental Health Treatment and Access
- Psychosomatic Disorders and Their Treatments
- Mental Health Research Topics
- Literature and Cultural Memory
- Geographies of human-animal interactions
- Gothic Literature and Media Analysis
- Visual Culture and Art Theory
- Space Science and Extraterrestrial Life
- Photography and Visual Culture
- Historical Influence and Diplomacy
- European history and politics
- Ecology, Conservation, and Geographical Studies
- Utopian, Dystopian, and Speculative Fiction
- Child and Adolescent Psychosocial and Emotional Development
- Bipolar Disorder and Treatment
- Historical, Literary, and Cultural Studies
- Neuroendocrine regulation and behavior
- German History and Society
- Archaeological Research and Protection
- Functional Brain Connectivity Studies
- German Colonialism and Identity Studies
University of Southern Denmark
2010-2024
Carnegie Mellon University
2021
Institute for Literature
2013-2020
Literaturarchiv
2019-2020
Ministry of Culture
2013-2018
Columbia University
2016
Central Institute of Mental Health
1998-2014
Heidelberg University
2013-2014
Innsbruck Medical University
2014
University Hospital Heidelberg
2014
The aim of this study was to investigate when social consequences in schizophrenia emerge, and what conditions give rise the disadvantage evident people suffering from schizophrenia.Early course studied a population-based sample 232 first illness-episode cases retrospectively onset admission, representative subsample 115 patients prospectively at six cross-sections over period 5 years. Data on non-specific negative symptomatology development compared with data an age- sex-matched control...
Using epidemiologic data, in an earlier study we formulated the hypothesis that estrogens can delay onset of schizophrenia females by raising vulnerability threshold for this disease. In animal experiments, Häfner and colleagues found evidence chronic estradiol treatment reduces sensitivity dopamine (D2) receptors brain. clinical presented article, as a further step examined antipsychotic properties human testing whether schizophrenic symptomatology varies with serum levels throughout...
Numerous studies have reported a lower mean age at first hospitalization for schizophrenia in males than females. For this finding not only gender difference onset of schizophrenia, but also other factors can be responsible. With the aim providing comprehensive analysis differences onset, symptomatology and course we started by testing hypothesis postulating hospitalization. By using Danish Mannheim psychiatric case registers analysed all hospital admissions related diagnoses previous...
Background Young people with self-experienced cognitive thought and perception deficits (basic symptoms) may present an early initial prodromal state (EIPS) of psychosis in which most the disability neurobiological schizophrenia have not yet occurred. Aims To investigate effects integrated psychological intervention (IPI), combining individual cognitive–behavioural therapy, group skills training, remediation multifamily psychoeducation, on prevention EIPS. Method A randomised controlled,...
For the investigation of early course schizophrenia starting from onset, standardised Interview for Retrospective Assessment Onset Schizophrenia was developed and validated. In a representative sample 267 first-admitted German schizophrenics broad diagnosis population 1.5 million, age at which different diagnostic onset definitions were satisfied, symptoms time interview, accumulation positive negative until first admission assessed. Comparison between two sexes three groups yielded hardly...
Using the Interview for Retrospective Assessment of Onset Schizophrenia (IRAOS), we assessed 170 first illness episodes with a nonpsychotic prodromat stage (73% population-based Age, Beginning, Course [ABC] study sample 232 schizophrenia from German population about 1.5 million). Conrad's (1958) and Docherty et al.'s (1978) models early course presume unidirectional compelling pat terns symptom manifestation. structural equation modeling, tested explanatory power stages as latent variables...
The ABC schizophrenia study aims at investigating sex differences in age of onset, symptoms and course schizophrenic paranoid disorders. For this purpose, we used case register data from Denmark Mannheim a directly examined sample first admissions (ABC sample). Danish included less clinical diagnoses more schizophrenia‐related disorders (acute reaction, states borderline schizophrenia) than the (case problem therefore was whether two datasets are comparable results valid. reason randomized,...
Sex differences in schizophrenic diseases have been known for a long time but also subject to long-term neglect by psychiatric epidemiological research, although study of these sex could, our opinion, yield valuable pointers pathogenic factors involved this group the aetiology which still awaits clarification. For reason we initiated large-scale investigations focussed on topic. The paper presented here discusses few initial results, based data Mannheim and National Danish Case Records own...
Over the last decade, drone technology has garnered critical attention across disciplinary fields, from engineering, military studies, law, and political science to landscape architecture scien...