- Spectroscopy and Chemometric Analyses
- Advanced biosensing and bioanalysis techniques
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Advanced Chemical Sensor Technologies
- Quantum Dots Synthesis And Properties
- Carbon and Quantum Dots Applications
- Bone Tumor Diagnosis and Treatments
- Sarcoma Diagnosis and Treatment
- Drug Transport and Resistance Mechanisms
- Electrochemical sensors and biosensors
- Protein Interaction Studies and Fluorescence Analysis
- Phytochemistry and Biological Activities
- Biosensors and Analytical Detection
- Spectroscopy Techniques in Biomedical and Chemical Research
- Advanced Nanomaterials in Catalysis
- Musculoskeletal synovial abnormalities and treatments
- Traditional Chinese Medicine Analysis
- Pesticide Residue Analysis and Safety
- Electrochemical Analysis and Applications
- Meat and Animal Product Quality
- Free Radicals and Antioxidants
- Identification and Quantification in Food
- DNA Repair Mechanisms
- Advanced Computational Techniques and Applications
Guiyang Medical University
2023-2025
Northeast Normal University
2022-2024
North China Electric Power University
2023
Yanbian University
2023
Tianjin Institute of Pharmaceutical Research (China)
2022
Guizhou University
2022
Nanjing Tech University
2022
Yunnan University
2022
Tea Research Institute
2022
Wenzhou Medical University
2021
Established herein is a radical-mediated C–H alkylation of enamides with cyclopropanols. An environmentally benign catalytic system iron salt and air used to permit the oxidative coupling process. The protocol demonstrates broad substrate scope, allowing stereoselective synthesis alkylated enamides. value this strategy further reflected by late-stage diversification complex cyclopropanol-containing molecules downstream transformations. Mechanistic studies reveal dual role in reaction.
As an effective method, the fingerprint technique, which emphasized whole compositions of samples, has already been used in various fields, especially identifying and assessing quality herbal medicines. High-performance liquid chromatography (HPLC) near-infrared (NIR), with their unique characteristics reliability, versatility, precision, simple measurement, played important role among all techniques. In this paper, a supervised pattern recognition method based on PLSDA algorithm by HPLC NIR...
In this paper, mid- and near-infrared spectroscopy fingerprints were combined to simultaneously discriminate 12 famous green teas quantitatively characterize their antioxidant activities using chemometrics. A supervised pattern recognition method based on partial least square discriminant analysis (PLSDA) was adopted classify the with different species quality grades, then optimized sample-weighted least-squares support vector machine (OSWLS-SVM) particle swarm optimization employed...
Celastrol (CEL), a pentacyclic triterpene compound, has been proven to have definite antipulmonary fibrosis effect. However, its direct targets for remain unknown. In this study, we designed and synthesized series of celastrol-based probes identify the in human pulmonary fibroblasts using an activity-based protein profiling strategy. Among many fished targets, identified key protein, cullin-associated neddylation-dissociated 1 (CAND1), which was involved fibroblast–myofibroblast...
Hyperlipidemia is characterized by a high level of blood lipid which poses serious threat to human health. Coix seed traditional crop medicine and food homology with wide range pharmacological actions. To make clear the attenuation effect coix against hyperlipidemia, low doses extract (CSE) were orally administered hyperlipidemia model mice developed high-fat diet (HFD). Our results showed that CSE notably improved liver pathological injury, oxidative stress, declined levels glucose in mice....
High-quality water-soluble N-acetyl-l-cysteine-capped CdTe quantum dots (QDs) have been synthesized through a hydrothermal route, which allows rapid preparation time (<1 h) and tunable emitting peaks (from 535 to 650 nm) with excellent yields as high 45%. The influences of different synthetic parameters upon the growth kinetics prepared QDs systematically studied. electron diffraction spectroscopy technique was employed examine impacts molar ratio reactants reaction on element compositions...
Fourier transform near-infrared (NIR) spectroscopy and mid-infrared (MIR) play important roles in all fingerprint techniques because of their unique characteristics such as reliability, versatility, precision, ease measurement. In this paper, a supervised pattern recognition method based on the PLSDA algorithm by NIR NIR-MIR fusion spectra has been established to identify geoherbalism Angelica dahurica from different regions authenticity Corydalis yanhusuo W. T. Wang. Comparing principle...
Abstract The sensitive detection of heavy metal ions with high toxicity and mobility is extremely important for environmental monitoring. In this study, nitrogen‐doped biochar (N‐BC) was synthesized using waste mushroom bran as a raw material, nitrogen atoms were successfully doped onto the surface via facile process an activation‐carbonation strategy. functional groups on enriched doping, roughness significantly improved. Experimental results showed that N‐BC efficient sensing material...
Hexaconazole is a widely used and frequently detected fungicide which also reported to be persistent in environment. The toxicity of Hex non-organisms such as reproductive toxicity, endocrine disrupting carcinogenic had been reported. However, study on the Hex-induced neurotoxicity rare mechanism still unclear. Therefore, this study, environmental related concentrations were chosen investigate effects nervous system from aspect biological rhythm under 90 d sub-chronic exposure. results...
ABSTRACT The interaction of trypsin with tetramethylpyrazine (TMP) and ferulic acid (FA) was studied using fluorescence, synchronous UV–vis absorption, circular dichroism (CD) three‐dimensional (3D) fluorescence spectra techniques. Using quenching calculations, the bimolecular constant ( k q ), apparent K SV effective binding a ) site number n were obtained. distance r between donor acceptor found to be 2.049 1.281 nm for TMP–trypsin FA–trypsin complexes. TMP FA can quench intensity by...