A5100858031- Cancer therapeutics and mechanisms
- Biochemical effects in animals
- Adenosine and Purinergic Signaling
- Advanced biosensing and bioanalysis techniques
- Asthma and respiratory diseases
- Foreign Body Medical Cases
- Hepatitis C virus research
- Muscle metabolism and nutrition
- Global Health and Epidemiology
- Catalytic Processes in Materials Science
- Mesoporous Materials and Catalysis
- Surgical Sutures and Adhesives
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Traumatic Ocular and Foreign Body Injuries
- Neonatal Respiratory Health Research
- RNA Interference and Gene Delivery
- Synthesis and Biological Evaluation
- Shoulder Injury and Treatment
- Catalysis and Oxidation Reactions
- Nitric Oxide and Endothelin Effects
- Hearing Loss and Rehabilitation
- Cardiac Ischemia and Reperfusion
- Biochemical Analysis and Sensing Techniques
- Medicinal Plants and Neuroprotection
Universal College of Medical Sciences
2023-2024
National University of Computer and Emerging Sciences
2024
College of Medical Sciences
2023-2024
Xinjiang University
2024
Lady Reading Hospital
2023
Combined Military Hospital
2023
National University of Medical Sciences
2023
East Carolina University
1995-2001
Medical University of South Carolina
2001
University of Lucknow
1974
The inhalation of nebulized adenosine causes bronchoconstriction in asthmatics. In order to explore whether endogenously produced may contribute the pathophysiologic aspects asthma, we measured concentrations bronchoalveolar lavage (BAL) fluid seven subjects with eight asymptomatic cigarette smokers, and normal subjects. mean concentration BAL from was 0.72 +/- 0.16 microM. Subjects asthma smokers had significantly increased fluid, 2.55 0.50 1.89 microM, respectively. Corrected for dilution...
EPI-2010 is a respirable antisense oligonucleotide (RASON), which selectively attenuates discordantly overexpressed adenosine A1 receptors in allergic lung (Nature 1997;385:721). In the present study, aerosolized [35S]-labeled (5 mg exposure; specific activity 0.055 Ci/mmol) was administered to normal rabbits by endotracheal tube assess biodistribution, route of elimination, and potential cardiovascular toxicity. The animals were killed at 0, 6, 24, 48, 72 h after inhalation EPI-2010....
SN-38 is an active metabolite of CPT-11. The poor solubility in any pharmaceutically acceptable solvent and pH-dependent activity has limited its clinical use. Our objective was to evaluate easy-to-use liposome-based formulation (LE-SN38) compare the antitumor with pro-drug CPT-11 against cancer cell lines human xenograft tumor models. cytotoxicity LE-SN38 determined four using sulforhodamine B assay. therapeutic efficacy tested colon (HT-29) breast (MX-1) models SCID mice. greater than 95%...
INTRODUCTIONThis study aims to assess the effectiveness of adjunctive treatments like transcutaneous electric nerve stimulation (TENS), therapeutic ultrasound (ThUs), and stabilization splint (SS) in combination with pharmacotherapy (PT) enhancing pain relief, mouth opening, lateral excursion, joint sound reduction, muscle tenderness improvement, jaw deflection patients temporomandibular disorders (TMDs), affecting masticatory muscles. MATERIAL AND METHODSThe involved 90 divided into three...
ABSTRACT A new palladium‐based catalyst system modified with dibenzofuran (DBF) was developed for acetylene hydrochlorination. The optimal Pd‐DBF/SAC the 0.5 wt% Pd loading and 15 DBF exhibits an elevated performance of 99.9% conversion vinyl chloride selectivity more than 400 h. Characterization analysis density functional theory (DFT) simulations revealed that presence oxygen‐containing species prevents reduction loss species, inhibits carbon deposition enhances HCl adsorbability,...
1. An inhibitor of cytoplasmic guanine deaminase rat liver was isolated from ;heavy mitochondrial' fraction after freezing and thawing treatment with Triton X-100. 2. Submitochondrial fractionation revealed that the localized in outer-membrane fraction. 3. The method purification inhibitor, involving precipitation (NH(4))(2)SO(4) chromatography on DEAE-cellulose, its precipitability by trichloroacetic acid pattern absorption u.v. indicated a protein. In confirmation, tryptic digestion...
Escalating transportation demands have mandated extensive construction of highways in proximity to residential zones, culminating heightened vehicular noise levels.This investigation centered on the assessment pollution across diverse sites Lahore, Pakistan, with a specific focus Lahore Ring Road (LRR) and surrounding regions.Variables including land utilization, road categorization, arboreal presence, physical impediments, distances between sources receivers were meticulously...
Objective: To determine the mean length of hospital stay term and late preterm infants with transient tachypnea newborn treated intravenous Furosemide compared to Control Group.
 Study Design: Quasi-experimental study.
 Place Duration Study: Combined Military Hospital, Kharian, from Apr Oct 2016.
 Methodology: All new-borns were included in study. One Group was given IV Furosemide, other taken as control. Two doses administered at 1 mg/kg 12 hours apart. The normal saline 01...
INTRODUCTION Pleomorphic adenoma is one of the most common benign salivary gland tumor affecting major glands mainly parotid approx. 80% but infrequently minor palate 7%. Salivary tumors are rare accounting only 2–3% occurring in head and neck region. The majority malignant nature. sites for where pleomorphic arises palates followed by lips cheek. This case report presents a treated successfully wide surgical excision with 1 cm healthy margin uninvolved anatomical barrier under general anesthesia.
Hemochromatosis, an iron metabolism disorder caused by overload, often runs in families. It leads to various issues like cardiomyopathy, liver cirrhosis, and hormonal imbalances. This article presents a unique case of secondary hemochromatosis resulting from repeated transfusions. A 15-year-old boy with severe beta-thalassemia major received about 600 units packed red blood cells over nine years. led clinical hypoparathyroidism subclinical hypothyroidism, affecting multiple organs. Elevated...
Foreign bodies are a common occurrence in pediatrics, which health care professionals usually encounter cases where children accidentally swallow foreign body or stick objects their ears nose. A child with stuck to the hard palate, however, is rare occurrence. embedded palate uncommon findings and may occasionally mimic oral lesions. In majority of cases, embedment happens infants who unable give history. We present case 9 months old boy for 4 weeks.