Cao Ruan

ORCID: 0000-0003-3781-7834
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About
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Research Areas
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology
  • Antibiotic Resistance in Bacteria
  • Cancer, Lipids, and Metabolism
  • Ferroptosis and cancer prognosis
  • Inflammasome and immune disorders
  • Lipid metabolism and biosynthesis
  • RNA modifications and cancer
  • Ideological and Political Education
  • interferon and immune responses
  • Infectious Diseases and Tuberculosis
  • Cancer Immunotherapy and Biomarkers
  • Cholesterol and Lipid Metabolism
  • Biochemical and Molecular Research

Chongqing University
2023-2025

Southwest University
2019-2021

Peking University
2010

Immune checkpoint inhibitor (ICI) therapy is a promising anti-tumor therapeutic strategy; however, its efficacy in solid tumors limited. Chromosome missegregation common various tumors; role tumor progression remains poorly understood, and correlation with ICI yet to be explored. Here, it found that increased chromosome promotes immune microenvironment, eventually immunotherapeutic efficacy, by triggering pyroptosis. yin yang 2 (YY2) identified as mitotic regulator, which upregulating BUB1B...

10.1002/advs.202409769 article EN cc-by Advanced Science 2025-02-04

Cell death resistance is a hallmark of tumor cells that drives tumorigenesis and drug resistance. Targeting cell resistance-related genes to sensitize decrease their threshold has attracted attention as potential antitumor therapeutic strategy. However, the underlying mechanism not fully understood. Recent studies have reported NeuroD1, first discovered neurodifferentiation factor, upregulated in various plays crucial role tumorigenesis. its involvement remains unknown. Here, we found...

10.1371/journal.pgen.1011098 article EN cc-by PLoS Genetics 2023-12-22

To explore the effect of voluntary service on medical student ideological and political education, this study researched who had attended 29th Olympic Game as a volunteer.The results showed, guides to build up their philosophy; improves professional morality; extracting experience from organize will benefit students' education. Key words: Voluntary service; Olympic Game; Medical student; Ideological education

10.3760/cma.j.issn.1673-677x.2010.02.025 article EN Chinese Journal of Medical Education 2010-04-01
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