A5089539745- Antiplatelet Therapy and Cardiovascular Diseases
- Platelet Disorders and Treatments
- Venous Thromboembolism Diagnosis and Management
- Chronic Lymphocytic Leukemia Research
- Hormonal and reproductive studies
- Blood Pressure and Hypertension Studies
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiovascular Health and Disease Prevention
- Blood groups and transfusion
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Sphingolipid Metabolism and Signaling
Universitätsmedizin Greifswald
2020-2022
University of Graz
1979
Platelets within one individual display heterogeneity in reactivity, size, age, and expression of surface receptors. To investigate the combined intraindividual contribution platelet receptor levels on reactivity platelets, we studied fractions large small platelets from healthy donors separated by using differential centrifugation. Size-separated were perfused over a collagen-coated to assess thrombus formation. Multicolor flow cytometry was used characterize resting stimulated...
Results from skin tests and radioallergosorbent test (penicilloyl G penicilloyl V) were compared in 76 patients with suspected penicillin hypersensitivity 22 control subjects without such clinical symptoms. The results also correlated to the history of adverse reactions levels total serum IgE. overall agreement between RAST was 89% patient group. Two symptoms professionally employed production; one them had circulating IgE-antibodies other exhibited positive tests. more frequently than test....
Aims: We report scale-up synthesis and characterization of a short nonfibrillar recombinant protein demonstrate that important functional properties fibrillar/native collagen in primary haemostasis are well mimicked.Methods: The biodesigned triple-helical NVH020, apparent MM 55 kDa, containing the binding motifs to VWF, α2β1, GPVI, was produced genetically modified yeast.It does not structure itself as fibrillar form but particulate one (atomic-force microscopy).Soluble water pH 7.4, it is...
Abstract Introduction Biomarkers for risk stratification of patients with cardiovascular disease are essential prevention. Ceramides play an important role during atherogenesis. For the C24:0/C16:0 ratio inverse association incident coronary artery and heart failure has been shown. Hence, ceramides may be a new predictive biomarker disease. Purpose We explored relation three specific (i.e. C16:0, C22:0 C24:0) their ratios subclinical atherosclerosis, assessed by carotid intima media...