Objectives To investigate willingness to use HIV pre-exposure prophylaxis (PrEP) and the likelihood of decreased condom among Australian gay bisexual men. Methods A national, online cross-sectional survey was conducted in April May 2011. Bivariate relationships were assessed with χ 2 or Fisher's exact test. Multivariate logistic regression analysis performed assess independent primary outcome variables. Results Responses from 1161 HIV-negative untested men analysed. Prior antiretroviral...

Background: In public health emergencies, evidence, intervention, decisions and translation proceed simultaneously, in greatly compressed timeframes, with knowledge advice constantly flux. Idealised approaches to evidence-based policy practice are ill equipped deal the uncertainties arising evolving situations of need. Key points for discussion: There is much learn from rapid assessment outbreak science approaches. These emphasise methodological pluralism, adaptive generation, intervention...

Viral outbreaks and public health emergencies obligate an urgent need for evidence to inform rapid responses. In the case of SARS-Cov-2, a novel virus linked fast-moving COVID-19 pandemic, m...

Individual in-depth, semi-structured interviews with 30 HIV positive Black Africans were conducted in London, UK. The focused upon experiential accounts of living HIV. transcribed and analysed for recurrent themes using interpretative phenomenological analysis. social context being a African the UK emerged as an important framework within which experience was positioned. In terms people's their own experiences HIV, diagnosis figured moment lives. majority participants surprised upset...

HIV has changed in the presence of recent biomedical technologies. In particular, development anti-retroviral therapies (ARVs) for treatment was a significant landmark history disease. Treatment with ARV drug regimens, which began 1996, enabled many thousands to live human immunodeficiency virus without progressing AIDS. Yet ARVs have also been fraught problems regimen compliance, viral resistance, and iatrogenic Besides intensifying technological ethical complexities medicine, drugs...

Sociology has a long-standing interest in the consumption of licit and illicit drugs, particularly as feminist concern with scholars highlighting ways which drugs are used regulatory technologies to control conduct subjectivities women other marginalised groups. This monograph flips focus from sociological means confining minoritised peoples, explore what they can do practice. Employing drug-user activist concept ‘narcofeminism’, it aims rethink how conceived sociology chart their role...

In this introduction, we address some of the complexities associated with emergence medicine’s bodies, not least as a means to ‘working body’ rather than simply producing critique medicine. We provide brief review recent discussions on how conceive medicine and its noting increasing attention now given technology or series technologies active in constituting multiplicity entities – diseases, experimental objects, individualization responsibility for health even precarity life. contrast what...

Expanding on the recent call for a 'critical medical humanities' to intervene in questions of ontology health, this article develops what we 'speculative' orientation such interventions relation some ontological commitments which contemporary biomedical cultures rest. We argue that crucial task is an approach treats it not as question first principles, but matter consequences images nature research practices espouse when they make claims evidence, well possible imagining different worlds...

Abstract This paper focuses on the relationship of HIV medical technologies to current styles practice and highlights issues posed by for those working and/or living with HIV. The examines anti‐retroviral combination therapies associated tests from perspective their prescribers. prescribers were interviewed during later part 2002 at three London clinics. Their comments, considered in light other recent studies field, suggest that are a transitional phase epidemic which informs identification...

This article explores problems posed by HIV anti-retroviral combination therapies focusing on the UK media promotion of Trizivir (a GlaxoSmithKline three-drugs-in-one tablet). Using substance figural in style feminist critiques science and borrowing from actor network theory, a synergistic relationship comprising HIV, anti-HIV drugs, drug manufacturers their media, medical publications, consumer representative treatment information mass is shown to construct worrisome set choices. The coming...

In this paper we examine the work of bioethics in enactment medically drugged bodies by focusing on development an oral pre-exposure chemo (drug) prophylaxis for preventing HIV, called PrEP. Our aim is to show how operationalisation mediate drug obscures a more complex and relational dynamic out which emerges qualities and, indeed, problematics incorporated into analysis drawn from small body literature trial affected communities, advocacy groups, researchers sponsors. particular, focus...

In this article we explore how two enactments of HIV – the UN’s AIDS Clock and clinical trials for an biomedical prevention technology or pre-exposure prophylaxis (PrEP) entail particular globalizing localizing dynamics. Drawing on Latour’s Whitehead’s concept proposition, Serres’ call a philosophy prepositions, use composite notion pre/pro-positions to trace shifting topological status HIV. For example, show PrEP emerges through entwinements standardization, protests against ethical...

We surveyed willingness to use pre-exposure prophylaxis (PrEP) and the likelihood of decreased condom among Australian gay bisexual men in 2011 2013 (n = 2384). Willingness PrEP declined from 28.2% 23.3% [adjusted odds ratio 0.83, 95% confidence interval (CI): 0.68 1.00, P 0.050]. was greatest with HIV-positive partners those who had taken HIV postexposure prophylaxis. Among willing PrEP, remained stable between (8.0% vs. 11.9%; adjusted 1.40, CI: 0.80 2.45, 0.23). A minority remain appear...

(2002). On the Biology of Sexed Subjects. Australian Feminist Studies: Vol. 17, No. 39, pp. 261-277.

This article takes up biomedical and public health concerns about the difficulty of generalizing or extrapolating measurements efficacy produced by method randomized control trial (RCT) to wider populations. While explanations for may be deduced from social studies science that reveal contingent situated nature findings, new conceptual tools are required allow practical value associated with possibility their extrapolation. We argue Alfred North Whitehead's concept 'abstraction' can provide...

Objective Assess the acceptability of HIV treatment as prevention and early antiretroviral among gay bisexual men in Australia any changes attitudes over time. Methods National, online, cross-sectional surveys were repeated 2011 2013. Changes to time assessed with multivariate analysis variance. The characteristics who agreed that prevented transmission thought was necessary identified logistic regression. Results In total, 2599 HIV-negative, untested HIV-positive participated (n = 1283 n...