A5065363265- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Poxvirus research and outbreaks
- COVID-19 and healthcare impacts
- Sex work and related issues
- Herpesvirus Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Syphilis Diagnosis and Treatment
- Virology and Viral Diseases
- Infective Endocarditis Diagnosis and Management
- Antibiotic Use and Resistance
- HIV Research and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Vaccine Coverage and Hesitancy
- Parasites and Host Interactions
- Gout, Hyperuricemia, Uric Acid
- Emergency and Acute Care Studies
- Reproductive tract infections research
- Cystic Fibrosis Research Advances
- Bacillus and Francisella bacterial research
- Long-Term Effects of COVID-19
- Infection Control and Ventilation
- Adolescent Sexual and Reproductive Health
- Bone and Joint Diseases
George Washington University Virginia Campus
2025
George Washington University
2017-2025
University of Mississippi Medical Center
2016-2023
Jackson Memorial Hospital
2017-2021
Washington University Medical Center
2018
Veterans Health Administration
2018
AIDS United
2017
Johns Hopkins University Center for AIDS Research
2017
State Street (United States)
2017
University of Carabobo
2007
Abstract Background Information on outcomes of methicillin-susceptible and -resistant Staphylococcus aureus (MSSA MRSA, respectively) bacteremia, particularly readmission, is scarce requires further research to inform optimal patient care. Methods We performed a retrospective analysis using the 2014 Nationwide Readmissions Database, capturing 49.3% US hospitalizations. identified MSSA MRSA bacteremia International Classification Diseases, Ninth Revision, Clinical Modification among patients...
Letters18 August 2022Monkeypox Virus–Associated Severe Proctitis Treated With Oral Tecovirimat: A Report of Two CasesFREEJose Lucar, MD, Afsoon Roberts, Karl M. Saardi, Rebecca Yee, PhD, Marc O. Siegel, and Tara N. Palmore, MDJose MDDivision Infectious Diseases, George Washington University School Medicine Health Sciences, Washington, DC (J.L., A.R., M.O.S., T.N.P.), MDDepartment Dermatology, (K.M.S.), PhDDepartment Pathology, (R.Y.), T.N.P.)Author, Article, Disclosure...
People with HIV (PWH) are disproportionally affected by mpox and at risk of severe complications. We assessed knowledge, adoption preventive behaviors, vaccination attitudes among PWH enrolled in a longitudinal cohort Washington, DC, the DC Cohort. conducted uni- multivariable analyses comparing participants status group, multinomial regression to identify factors associated vaccine acceptance. Among 430 PWH, 378 (87.9%) were aware mpox. 373 data, 101 (27.1%) vaccinated, 129 (34.6%) planned...
Abstract Background Washington, DC, has one of the highest rates HIV infection in United States. Sexual intercourse is leading mode transmission, and sexually transmitted infections (STIs) are a risk factor for acquisition transmission. Methods We evaluated incidence demographic factors associated with chlamydia, gonorrhea, syphilis among HIV-infected persons enrolled at 13 DC Cohort sites from 2011 to 2015. Using Poisson regression, we assessed covariates incident STIs. also examined viral...
Abstract Background The incidence of invasive nontypeable H. influenzae (NTHi) is on the rise, and NTHi now causes majority infections across all age groups. While these presentations are usually among people at extremes age, we observed a recent increase in cases adults our institution compared to previous years. Here, report their clinical presentation subsequent molecular epidemiology investigation. Characteristics Patients With Invasive Nontypeable Haemophilus Infection, GW Hospital,...
Abstract Background Since the approval of CAB/RPV LA, over 50 patients followed in MFA Infectious Diseases clinic have transitioned to long-acting injectable CAB/RPV. Several were found low-level viremia despite no documented resistance either component LA. We investigated incidence and associated risk factors this patient population. Methods reviewed charts all who received at least 3 doses LA evaluated HIV viral loads (VL) ≥50 copies. Those categorized into groups: a) blips – isolated VL...
Objective A rise in incidence of STIs has been noted the USA and District Columbia (DC). We aim to describe changes incident among persons care for HIV Washington, DC as well trends viral load those with STIs. Methods conducted a retrospective Cohort analysis (n=7810) measuring STI (syphilis, gonorrhoea chlamydia) incare (ICVL) percentage all loads less than limit detection (%<LLOD) by year (2012–2016) Results From 2012 2016, increased: chlamydia from 2.1 3.4 cases/100 person-years...
To describe the demographics, clinical characteristics, and outcomes of hospitalized adults with coronavirus disease 2019 (COVID-19) in an academic medical center southern United States.Retrospective, observational cohort study all adult patients (18 years older) consecutively admitted laboratory-confirmed severe acute respiratory syndrome-coronavirus-2 infection between March 13 April 25, 2020 at University Mississippi Medical Center. All either survived to hospital discharge or died during...
The presentation of anaplastic lymphoma kinase protein (ALK)-negative large cell (ALCL) in bone is rare. We describe a patient with ALK-negative ALCL presenting clinical and radiographic findings suggesting osteomyelitis 6 months after left rotator cuff repair surgery. A review the characteristics primary involvement presented. should be considered patients not responding to therapies for osteomyelitis.
Necrotizing fasciitis is a deep-seated subcutaneous tissue infection that commonly associated with streptococcal toxic shock syndrome (TSS). Surgical debridement plus penicillin and clindamycin are the current standard of care. We report case necrotizing TSS where linezolid was added after failure to improve therapy. Briefly isolation Streptococcus pyogenes from cultures, patient underwent two surgical procedures changed care While hemodynamically stable, patient’s wounds, leukocytosis,...
Abstract We observed a higher rate of blood-culture contamination during the COVID-19 pandemic at our institution compared to prepandemic period. Given potential implications blood in antibiotic and diagnostic test utilization as well added cost, it is imperative continue efforts minimize these episodes pandemic.
The high proportion of people with HIV (PWH) in the 2022-2023 mpox outbreak has raised questions surrounding association between and mpox. objectives this study were to evaluate engagement HIV-associated healthcare diagnosis, as well characterize cases among PWH. DC Cohort is a longitudinal cohort PWH Washington, DC. We conducted 5:1 (controls:cases) nested case-cohort on male participants, matching age care site. Cases participants an identified diagnosis. Conditional logistic regression...
There is ongoing debate regarding the role of aerosols in transmission SARS-CoV2 health care environment. Here, we report a case which multiple operating room providers were exposed to patient with asymptomatic infection during prolonged orthopedic surgical intervention and had no evidence COVID-19 14-day post-exposure period.
Outpatient parenteral antimicrobial therapy (OPAT), when required, is beneficial to patients and healthcare systems by reducing hospital length-of-stay, providing cost savings, improving patient satisfaction.The purpose of this study determine readmission rates associated risk factors in receiving OPAT at home.This retrospective included hospitalized 15 years older who were discharged on intravenous via home between January 2018 December 2019. Patients antimicrobials a skilled nursing...
Abstract Introduction The COVID-19 pandemic has created substantial interruptions in healthcare presenting challenges for people with chronic illnesses to access care and treatment services. We aimed assess the impact of on HIV delivery by characterizing pandemic-related clinic-level services mitigation strategies that were developed address them. Methods data comes from a site assessment survey conducted DC Cohort, an observational clinical cohort PWH receiving at 14 outpatient clinics...
Abstract Background Candida auris is deemed an urgent threat because it spreads easily in healthcare facilities, can cause severe infections with high mortality rates, and resistant to antifungal agents. Since the onset of COVID-19 pandemic, we detected a rise inpatient C. cases. We describe series cases at tertiary hospital Washington, DC. Cases by date initial sample collection, GW Hospital, DC, March 2020 - April 2023. Methods reviewed charts inpatients between 3/2020-4/2023. Patients...
Abstract Background A high proportion of people with HIV (PWH) in the 2022-2023 mpox outbreak (approx. 40% US cases) has raised questions about association between and mpox. Increased encounters healthcare system may be contributing to this association. This study sought elucidate whether detection bias drives relationship by determining engagement care STI screening are associated having an diagnosis. Methods We conducted a 5:1 matched case-control among DC Cohort participants, longitudinal...
In Brief The role of immunoglobulins in control strongyloidiasis has not been well appreciated. This case disseminated with vancomycin-resistant Enterococcus faecium meningitis illustrates the critical preventing Strongyloides hyperinfection syndrome. Disseminated stronyloidiasis infection is usually associated concommitant steroid therapy or HTLV-1 infection. this condition well-recognized. diagnosis may be missed patients who lack traditional risk factors. important help to explain why HIV...