A5083081547- Laser Applications in Dentistry and Medicine
- Bone Tissue Engineering Materials
- Dental materials and restorations
- Dental Erosion and Treatment
- Innovative Microfluidic and Catalytic Techniques Innovation
- Fluid Dynamics and Thin Films
- biodegradable polymer synthesis and properties
- Dental Implant Techniques and Outcomes
- Heat Transfer and Boiling Studies
- Blood properties and coagulation
- Orthopaedic implants and arthroplasty
- NMR spectroscopy and applications
- Advanced Drug Delivery Systems
- Advanced Nanomaterials in Catalysis
- Advanced NMR Techniques and Applications
- Fluid Dynamics and Mixing
- Heat Transfer and Optimization
- Coronary Interventions and Diagnostics
- Microfluidic and Capillary Electrophoresis Applications
- Cardiovascular Health and Disease Prevention
- Minerals Flotation and Separation Techniques
- Hydrocarbon exploration and reservoir analysis
- Chemical Synthesis and Characterization
- Electrohydrodynamics and Fluid Dynamics
- Laser Material Processing Techniques
University of Manchester
2003-2025
Hexcel (United Kingdom)
2025
National Centre of Scientific Research "Demokritos"
2016-2024
Institute of Science and Technology
2020
University of Leeds
2015-2019
Aristotle University of Thessaloniki
2010-2013
For the computational design of new polymeric materials, accurate methods for determining glass transition temperature (Tg) are required. We apply an ensemble approach in molecular dynamics (MD) and examine its predictions Tg their associated uncertainty. separate uncertainty into aleatoric contributions arising from dynamical chaos that due to scenarios chosen compute Tg. propose a scenario computing Tg, where density–temperature behavior is computed by running all temperatures...
A series of poly(lactic acid) (PLA)/biochar (BC) bio-composites filled with low amounts (1–5 wt%) BC were prepared and characterized. The synthesis involved the in situ ring-opening polymerization (ROP) lactide presence two different types named SWP550 SWP700, having been produced by pyrolysis softwood pellets at temperatures, 550 700 °C, respectively. characterized complementary techniques. successful PLA PLA/BC was directly demonstrated formation new bonds, most probably between BC....
Mesoporous silica-based nanoparticles (MSNs) are considered promising drug carriers because of their ordered pore structure, which permits high loading and release capacity. The dissolution Si Ca from MSNs can trigger osteogenic differentiation stem cells towards extracellular matrix calcification, while Mg Sr constitute key elements bone biology metabolism. aim this study was the synthesis characterization sol–gel-derived co-doped with Ca, Sr. Their physico-chemical properties were...
Bio-based poly(lactic acid) (PLA) composite films were produced using unmodified soda micro- or nano-lignin as a green filler at four different contents, between 0.5 wt% and 5 wt%. The PLA-lignin polymers synthesized by solvent casting to prepare masterbatch, followed melt mixing. composites then converted into films, evaluate the effect of lignin content size on their physicochemical mechanical properties. Differential scanning calorimetry (DSC), supported polarized light microscopy (PLM),...
Biodegradable polymers offer a promising alternative to the global plastic problems and especially in last decade, microplastics problems. For first time, samples of poly(butylene succinate) (PBSu) biocomposites containing 1, 2.5, 5 wt% biochar (BC) were prepared by situ polymerization via two-stage melt polycondensation procedure. BC was used as filler for PBSu improve its mechanical properties, thermal transitions, biodegradability. The structure synthesized examined 1H 13C nuclear...
Direct laser sintering on hard tissues is likely to open new pathways for personalised medicine. To minimise irradiation damage of the surrounding soft tissues, lasers operating at wavelengths that are 'safe' and biomaterials with improved optical properties required. In this work demonstrated use an ultrafast, femtosecond (100 fs) pulsed a wavelength 1045 nm two existing calcium phosphate minerals (brushite hydroxyapatite) which have been after doping iron (10 mol%). Femtosecond caused...
Scaffolds and implants in orthopaedics regenerative dentistry usually fail because of bacterial infections. A promising solution would be the development biomaterials with both significant potential enhanced antibacterial activity. Working towards this direction, fluorapatite was synthesised doped Sr2+ Ce3+ ions order to tailor its properties. After experiments four common bacteria (i.e. E. Coli, S. Aureus, B. Subtilis, Cereus), it found that undoped fluorapatites present better response...
Silica-based ceramics doped with calcium and magnesium have been proposed as suitable materials for scaffold fabrication. Akermanite (Ca2MgSi2O7) has attracted interest bone regeneration due to its controllable biodegradation rate, improved mechanical properties, high apatite-forming ability. Despite the profound advantages, ceramic scaffolds provide weak fracture resistance. The use of synthetic biopolymers such poly(lactic-co-glycolic acid) (PLGA) coating improves performance tailors their...
Abstract We study experimentally the flow of non-wetting ganglia during co-injection n -heptane and water in a predominantly 2D PMMA micromodel, which is constructed based on stochastic digital algorithm. The dynamics phase distribution patterns are recorded optically post-processed using cluster identification motion tracking algorithms order to characteristics interactions between mobile stranded populations. focus primarily effects capillary number (Ca) ratio injection rates ( Q )...
In this study we compare three droplet microreactors for the synthesis of cerium oxide nanoparticles (CONs) and calcium phosphate crystals (CaPs) discuss their suitability long-term, continuous operation. The conditions were controlled by manipulating flow rate ratio phase to dispersed (Qc/Qd), which is a crucial factor influencing formation (DF) size. After identifying appropriate operating (droplet size between 400 500 μm), experiments conducted test operation microreactors. Among designs,...
Magnetic hybrid inorganic/organic nanocarriers are promising alternatives for targeted cancer treatment. The present study evaluates the preparation of manganese ferrite magnetic nanoparticles (MnFe2O4 MNPs) encapsulated within Paclitaxel (PTX) loaded thioether-containing ω-hydroxyacid-co-poly(d,l-lactic acid) (TEHA-co-PDLLA) polymeric nanoparticles, combined hyperthermia and chemotherapy treatment cancer. Initially, TEHA-co-PDLLA semitelechelic block copolymers were synthesized...
Dicalcium Phosphate Dihydrate (DCPD) mineral scaffolds alone do not possess the mechanical flexibility, ease of physicochemical properties' tuneability or suitable porosity required for regenerative bone scaffolds. Herein, we fabricated highly porous freeze-dried chitosan embedded with different concentrations minerals, i.e., 0, 20, 30, 40 and 50 (wt)%. Increasing DCPD concentration led to increased scaffold crystallinity, where % crystallinity CH, 40, 50-DCPD was determined be 0.1, 20.6,...
Tooth hypersensitivity is a growing problem affecting both the young and ageing population worldwide. Since an effective permanent solution not yet available, we propose new methodology for restoration of dental enamel using femtosecond lasers novel calcium phosphate biomaterials. During this procedure irradiated mineral transforms into densified layer acid resistant iron doped β-pyrophosphate, bonded with surface eroded enamel. Our aim therefore to evaluate as potential replacement material...
A radical new methodology for the exogenous mineralization of hard tissues is demonstrated in context laser-biomaterials interaction. The proposed approach based on use femtosecond pulsed lasers (fs) and Fe3+-doped calcium phosphate minerals (specifically this work fluorapatite powder containing Fe2O3 nanoparticles (NP)). layer synthetic applied to surface eroded bovine enamel irradiated with a fs laser (1040 nm wavelength, 1 GHz repetition rate, 150 pulse duration 0.4 W average power). NPs...
The calcium phosphate is the main mineral constituent of bone. Although there has been significant amount research on finding ideal synthetic bone, no suitable scaffold material yet found. In this investigation, iron doped brushite (CaHPO4·2H2O) investigated for osteogenic potential and mechanical properties. synthesis iron-oxide doping in form Fe2+,3+-ions were carried out using solution based method which ammonium hydrogen nitrate solutions used stoichiometric ratio synthesizing...
Bone healing is a complex process, and if not managed successfully, it can lead to non-union, metal-work failure, bacterial infections, physical psychological patient impairment. Due the growing urgency minimise antibiotic dependency, alternative treatment strategies, including use of nanoparticles, have attracted significant attention. In present study, cerium oxide nanoparticles (Ce
Yttria-stabilized zirconia nanoparticles can be applied as fillers to improve the mechanical and antibacterial properties of luting cement. The aim this study was synthesize yttria-stabilized by sol-gel method investigate their composition, structure, morphology biological properties.Nanopowders ZrO2 7 wt% Y2O3 (nY-ZrO) were synthesized sintered at three different temperatures: 800, 1000 1200 °C, size investigated. biocompatibility investigated with human gingival fibroblasts (hGFs), while...