A5041315704- Microfluidic and Bio-sensing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Nanopore and Nanochannel Transport Studies
- Granular flow and fluidized beds
- Electrostatics and Colloid Interactions
- Material Dynamics and Properties
- Lattice Boltzmann Simulation Studies
- stochastic dynamics and bifurcation
- Hydraulic Fracturing and Reservoir Analysis
- Groundwater flow and contamination studies
- Drug Solubulity and Delivery Systems
- Injection Molding Process and Properties
- Particle Dynamics in Fluid Flows
- Micro and Nano Robotics
- Aerosol Filtration and Electrostatic Precipitation
- NMR spectroscopy and applications
- Landslides and related hazards
- Innovative Microfluidic and Catalytic Techniques Innovation
- Nanomaterials and Printing Technologies
- Pickering emulsions and particle stabilization
- Advanced Thermodynamics and Statistical Mechanics
- Rheology and Fluid Dynamics Studies
- Nonlinear Dynamics and Pattern Formation
- Fractional Differential Equations Solutions
- Electrowetting and Microfluidic Technologies
Rutgers, The State University of New Jersey
2016-2025
State of New Jersey
2023
University of Buenos Aires
1998-2023
Rutgers Sexual and Reproductive Health and Rights
2017
Johns Hopkins University
2005-2014
Physical Sciences (United States)
2012
City University of New York
2002-2006
City College of New York
2000-2005
Comisión Nacional de Energía Atómica
1999
Balseiro Institute
1997-1999
We study an ad hoc extension of the lattice Boltzmann method that allows simulation non-Newtonian fluids described by generalized Newtonian models. extensively test accuracy for case shear-thinning and shear-thickening truncated power-law in parallel plate geometry, show relative error compared to analytical solutions decays approximately linear with resolution. Finally, we also tested reentrant-flow which shear rate is no longer a scalar presence two singular points requires high order...
We performed macroscopic experiments on the motion of a sphere through an array obstacles that highlight deterministic nature lateral displacements lead to particle separation in microfluidic systems. The spheres is irreversible and displays directional locking. locking directions can be predicted with single parameter distinguishes between reversible particle-obstacle collisions. These results stress need incorporate interactions predict movement non-Brownian passing periodic array.
Hypoxia plays an important role in vascular development through hypoxia-inducible factor-1alpha (HIF-1alpha) accumulation and downstream pathway activation. We sought to explore the vitro response of cultures human embryonic stem cells (hESCs), induced pluripotent (iPSCs), endothelial progenitor (hEPCs), umbilical cord vein (HUVECs) normoxic hypoxic oxygen tensions. first measured dissolved (DO) media adherent atmospheric (21% O(2)), physiological (5% conditions (1% O(2)). In both hEPCs...
The dynamics of macroscopically homogeneous sheared suspensions neutrally buoyant, non-Brownian spheres is investigated in the limit vanishingly small Reynolds numbers using Stokesian dynamics. We show that complex can be characterized as a chaotic motion phase space and determine dependence largest Lyapunov exponent on volume fraction ϕ. also offer evidence responsible for loss memory evolution system demonstrate this correlation space. at microscopic level individual particles shown terms...
The permeability anisotropy that results from a shear displacement between the complementary self‐affine walls of rough fracture is investigated. Experiments in which dyed fluid radially injected into transparent displaces one are presented. A clear observed presence displacements and allows us to estimate ratio permeabilities for flows parallel perpendicular . simple model accounts development channels qualitatively explains these predicts decreasing (increasing) linearly with variance...
We investigate the two-dimensional continuous size-based separation of suspended particles in gravity-driven deterministic lateral displacement (g-DLD) devices. The are driven through a periodic array cylindrical obstacles under action gravity. perform experiments covering entire range forcing orientations with respect to and identify specific angles that would lead vector separation, which different migrate, on an average, directions. A simple model, based induced trajectory particle by...
Abstract In fractures where surface fluctuations are large compared to their aperture ( narrow ), the flow is forced move in tortuous paths that produce additional viscous friction and subject inertia effects. We consider relation between magnitude of roughness onset inertial effects pressure driving through a single open fracture. performed experiments systematically varying average fracture covering wide range Reynolds numbers. For each aperture, we analyze data terms Forchheimer equation...
We investigate the dynamics of a non-Brownian sphere suspended in quiescent fluid and moving through periodic array solid obstacles under action constant external force by means Stokesian simulations. show that presence non-hydrodynamic, short-range interactions between sphere, particle becomes locked into trajectories with an average orientation coincides one lattice directions is, general, different from direction driving force. The locking angle depends on details non-hydrodynamic could...
We present a method to characterize the wettability of powders, based on penetration dynamics sessile drop deposited slightly compressed powder bed. First, we show that direct comparison wetting properties different liquids is possible without having solve three-dimensional liquid problem, by considering appropriate dimensionless variables. contact area between and bed remains constant during most process demonstrate as result, evolution volume given universal function time, with no...
Recently, analytical solutions of a nonlinear Fokker-Planck equation describing anomalous diffusion with an external linear force were found using nonextensive thermostatistical Ansatz. We have extended these to the case when homogeneous absorption process is also present. Some peculiar aspects interrelation between deterministic force, diffusion, and are discussed.
We investigate the transport and separation of overdamped particles under action a uniform external force in two-dimensional periodic energy landscape. Exact results are obtained for deterministic square lattice parabolic, repulsive centers that correspond to piecewise-continuous linear-force model. The trajectories commensurate with obstacle exhibit phase-locking behavior particle moves at same average migration angle range orientation force. as function has Devil's staircase structure....
We investigate the separation of drops in force-driven deterministic lateral displacement (f-DLD), a promising high-throughput continuous method microfluidics. perform scaled-up macroscopic experiments which settle through square array cylindrical obstacles. These demonstrate capabilities-and provide insight for design-of f-DLD multiple sizes, including that are larger than gaps between cylinders and exhibit substantial deformation as they move array. show any orientation driving force...
We present experimental results of solute transport in porous samples made packings activated carbon grains. Exchange experiments, where the tagged solution initially saturating medium is replaced with same without tracer, are accurately described by macroscopic equations. On other hand, desorption water, concentration exhibits a power-law decay for long times, which requires more detailed, mesoscopic description. reproduce this behavior within continuous-time random-walk approach, waiting...
Transport properties of three-dimensional self-affine rough fractures are studied by means an effective-medium analysis and numerical simulations using the Lattice-Boltzmann method. The results show that approximation predicts right scaling behavior permeability velocity fluctuations, in terms aperture fracture, roughness exponent, characteristic length fracture surfaces, limit small separation between surfaces. is also investigated as a function normal lateral relative displacements it...
The stochastic transport of suspended particles through a periodic pattern obstacles in microfluidic devices is investigated by means the Fokker-Planck equation and numerical simulations. Asymmetric arrays have been shown to induce continuous separation DNA molecules, with different size migrating directions within microdevice (vector separation). We show that tracer only occurs presence permeating driving force nonzero normal component at surface solid obstacles, arises from differences...
Dissipative particle dynamics (DPD) has recently attracted great interest due to its potential simulate the of colloidal particles in fluidic devices. In this work, we explore validity DPD reproduce hydrodynamic interaction between a suspended and confining solid walls. We first show that relatively large Schmidt number fluid can be obtained by increasing ratio strength dissipative force kinetic energy particles. then measure mobility diffusion coefficient good agreement with predicted...
Solvent-induced interactions produce the kinetic trapping of nanoparticles at nanoscale particle–wall separations.
This work explores label-free biosensing for rapid COVID-19 detections. Specifically, a novel electronic platform utilizing microfabricated nanowell-based impedance sensors.
Tracer diffusion and hydrodynamic dispersion in two-dimensional fractures with self-affine roughness are studied by analytic numerical methods. Numerical simulations were performed via the lattice-Boltzmann approach, using a boundary condition for tracer particles that improves accuracy of method. The reduction diffusive transport, due to fractal geometry fracture surfaces, is analyzed different apertures. In limit small aperture fluctuations we derive correction coefficient terms...