- Advanced Radiotherapy Techniques
- Breast Cancer Treatment Studies
- Glioma Diagnosis and Treatment
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Digital Radiography and Breast Imaging
- Brain Metastases and Treatment
- AI in cancer detection
- Radiomics and Machine Learning in Medical Imaging
- Radiation Detection and Scintillator Technologies
- Advances in Oncology and Radiotherapy
- Advanced X-ray and CT Imaging
- Prostate Cancer Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Neuroblastoma Research and Treatments
- Prostate Cancer Treatment and Research
- Management of metastatic bone disease
- Ultrasound and Hyperthermia Applications
- Breast Lesions and Carcinomas
- Global Cancer Incidence and Screening
- Neurogenesis and neuroplasticity mechanisms
- Lipid Membrane Structure and Behavior
- Radiopharmaceutical Chemistry and Applications
- Breast Implant and Reconstruction
Ospedale Policlinico San Martino
2014-2025
Alleanza Contro il Cancro
1992-2013
Istituti di Ricovero e Cura a Carattere Scientifico
2011-2013
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2012
National Cancer Research Institute
2012
International School of Trieste
2010
Martin University
1993
University of Genoa
1992
Abstract Purpose This work introduces BreastWatch, a Varian Eclipse script tool designed to help medical physicists, dosimetrists, and radiation oncologists easily inspect improve External Beam Breast Treatment (EBBT) plans using automatic evaluation of protocol dose‐constraints enhanced by Community‐Based approach. Methods BreastWatch examines EBBT Plans Plan Sums, automatically testing the plan's DVH against built‐in international (NRG RTOG1005, ICR Fast‐Forward, FAST, EUROPA 1.2)...
To compare breast density estimated from two-dimensional full-field digital mammography (2D FFDM) and tomosynthesis (DBT) according to different Breast Imaging-Reporting Data System (BI-RADS) categories, using automated software.Institutional review board approval written informed patient consent were obtained. DBT 2D FFDM performed in the same patients allow within-patient comparison. A total of 160 consecutive (mean age: 50±14 years; mean body mass index: 22±3) included create paired data...
LIAC® and NOVAC are two mobile linear accelerators dedicated to intraoperative radiation therapy (IORT), generating electron beams in the energy range of 3-12 MeV. Due high dose-per-pulse (up 70 mGy per pulse), 2003 Italian National Institute Health (ISS) stated that "for measure dose water reference conditions, ionization chambers cannot be employed no published dosimetry protocol can used". As a consequence, ferrous sulphate (or, alternatively alanine) was recommended. Based on...
The aim of the present work was to analyse impact mild hypofractionated radiotherapy (RT) infra-supraclavicular lymph nodes after axillary dissection on late toxicity.From 2007 2012, 100 females affected by breast cancer (pT1- T4, pN1-3, pMx) were treated with conservative surgery, Axillary Node Dissection (AND) and loco-regional (whole plus fossa). metastases confirmed in all women. median age at diagnosis 60 years (range 34-83). Tumors classified according molecular characteristics:...
After radical prostatectomy (RP) radiotherapy (RT) plays a role, both as adjuvant or salvage treatment. If negative features are present such extracapsular extension, seminal vesicle invasion, lymph and positive surgical margins, RT after RP reduces the risk of recurrence, although it is associated with an increased acute late toxicities. An intensified delivered in shortened time could improve clinical outcome be safely combined hormonal therapy (HT). The aim this study was to determine...
We analysed 300 patients X rayed with digital breast tomosynthesis (DBT), full-field mammography (FFDM) and ‘COMBO’ (single view both in FFDM DBT a single compression)—Hologic Selenia Dimension—W/Rh–Ag–Al: three different anode-filter combinations—automatic exposure control modalities. Examination parameter data collection (EPDC) ‘in vivo’ dosimetry using metal oxide semiconductor field effect transistor (MOSFET) were utilised to determine compare entrance skin air kerma (ESAK) average...
Ruthenium ophthalmic applicators are energetic beta ray sources, supplied in several shapes and dimensions, used intraocular tumor therapy. Because of their small the determination dosimetric characteristics represents a technical challenge. We developed semi‐automatic method to define surface dose, dose distribution, percentage depth such using radiochromic media. These detectors consist thin (7 μm) radiation sensitive layer on polyester base (100 μm total thickness) changing color as...
To evaluate local recurrence (LR) in women with early breast cancer (BC) who underwent intraoperative radiation therapy electrons particles (IORT-E) or adjuvant hypofractionated external radiotherapy (HYPOFX).We retrospectively analyzed 470 patients BC treated at our center from September 2009 to December 2012. 235 were breast-conserving surgery and immediate IORT-E (21 Gy/1 fraction) while wide excision followed by whole-breast irradiation. Radiotherapy modality was chosen according an...
Aim . To evaluate the toxicity of a hypofractionated schedule for primary radiotherapy (RT) prostate cancer as well value nadir PSA (nPSA) and time to (tnPSA) surrogate efficacy treatment. Material Methods Eighty patients underwent by Helical Tomotherapy (HT). A dose 70.2 Gy was administered in 27 daily fractions 2.6 Gy. Acute late toxicities were graded on RTOG/EORTC scales. The nPSA tnPSA treated with exclusive RT compared an equal cohort 20 conventional fractionation standard conformal...