The chicken gonadotropin-releasing hormone receptor (GnRH-R) is notable for having a cytoplasmic C-terminal tail, which not present in the mammalian GnRH-Rs. We report here that tail mediates rapid agonist-promoted internalization. GnRH-R mediated internalization of (GnRH) agonist (125I[His5-D-Tyr6]GnRH) at rate 11.3%.min-1, compared with only 0.71 %.min-1 human GnRH-R. To determine whether presence was responsible more kinetics we truncated after Ile336 residue (S337stop). Receptor-mediated...

Bioremediation using microorganisms offers a sustainable approach to addressing hydrocarbon contamination. This study explores biosurfactant production by Yarrowia lipolytica IMUFRJ 50682 during crude oil and asphaltene-free fraction biodegradation in corn steep liquor (CSL)-based media. By evaluating CSL concentrations (5–30 g/L) combinations with glucose, molasses, oil, this demonstrates that is an effective nutrient source for supporting microbial growth production. The highest...

The objective was to evaluate markers of muscle damage (CK, lactate, and LDH) after combat. This study followed a multiple-case design. research focused on three elite Para Jiu-Jitsu athletes aged 40-50 years with transfemoral amputations. Pre-combat post-combat blood samples were collected from the participants, LDH, CK levels analyzed. All increased fight in all participants (lactate - Δ% mean = 878%; LDH 23.6%; CPK % 124.1%; CPK-MB 555.4). Lactate similar among within reference values,...

Este relato de experiência em educação médica é baseado um caso que teve como objetivo descrever a importância do manejo clínico integrado pacientes com fibromialgia e comorbidades psiquiátricas, enfatizando o papel dos Centros Atenção Psicossocial (CAPS). Por meio uma análise temática, paciente apresentava sofrimento psicológico significativo, incluindo sintomas ansiedade transtorno obsessivo-compulsivo, insônia psicóticos. O tratamento incluiu prescrição quetiapina, juntamente...

Purpose: Evidence indicates that muscle injury caused by exercise can lead to functional, biochemical, and clinical damage. These outcomes encompass an intrinsic potential understand the real magnitude of interpretation classic signs in sport environments monitor athletes, contributing specific actions. However, little or no research has explored general behavior variables presented response paradesportivo Brazilian jiu-jitsu. The objective this study was investigate physiological through...

Abstract We have been using sportomics to understand hypermetabolic stress. Cross Combat (CCombat) has recently initiated as a high-intensity functional training method inspired by CrossFit. used CCombat session induce metabolic stress and evaluated its effects on hydration kidney function. Blood samples were collected from 16 elite-level professional male athletes engaged in sessions over 96-h protocol. myoglobin increased ~ 3.5-fold (119 ± 21 369 62 nmol/L; p = .001) response the protocol,...

Background Reliable clinical tests capable of measuring resistance are important tools for rehabilitation. One alternative that has recently increased in popularity is the use elastic tubes, which stand out being easy to handle, low cost, practical, and feasible. Objective Analyze test-retest reliability knee extensors muscle fatigue test (FRT) with tubes. Methods A total 116 healthy young males, aged between 18 30 years old, participated study. Participants performed three pre-test stages:...

The participation of judo athletes with disabilities in competitions has increased over the years as well burden sports-related injuries and illnesses this population. However, there is limited knowledge about different disabilities.To investigate prevalence disabilities, considering impairment groups, magnitude injury (ie, mechanism, nature, severity injury), specific body parts.Cross-sectional study (level evidence, 3).Brazilian Judo disabilities.Fifty-one (15 men 36 women) participated...

Occupational health is increasing in visibility within the scientific community and has become a field of international research discussions which occupational stress described as possible stressor.To analyze relationship between anxiety depression symptoms socioeconomic level among technical-administrative employees public university state São Paulo, Brazil.The sample comprised 89 participants. Data were obtained through Lipp's Inventory Stress Symptoms for adults to identify levels...

Abstract Introduction: Given the practicality and low cost of elastic devices, a comparison with conventional devices may be able to quantify gains from both tools for further conclusions. Objective: Compare effect resistance training (tubes band) (weight machines dumbbells) on body composition. Method: This is systematic review meta-analysis. The PubMed/MEDLINE, Embase, PEDro CENTRAL databases were searched earliest records July 25, 2018. Data described in standardized mean difference (SMD)...

The behavior of biochemical and immunological parameters investigated in the field conditions athletes is important to influence management recovery disease prevention as well as, support training program, improve physical conditioning associated with health performance. However, for amputee athletes, Brazilian jiu-jitsu paradesport practitioners, there are no published data date. Thus, objective this case study was quantify magnitude biochemical, hematological, urinary alterations after a...

Abstract Introduction Specifically in athletes with disabilities, investigations and biomechanical understanding seem to be even more relevant, as they provide data on how a certain type of disability limits sports practice also describe parameters that allow the suggestion relevant adaptations capable guaranteeing higher level comfort practitioners. Objective To patterns behavior during exercise discuss possible relationships between sport practiced. Methods This study performed search five...

Abstract Introduction: Muscle injuries show an incidence associated with extreme stretching, or even a high-intensity eccentric contraction. Such cause severe damage to athletes, including lower performance, withdrawal, and psychological distress. In this scenario, the study of effective preventive methods is indispensable factor in routine professional reduce injuries. Objective: To verify effectiveness three different interventions (warm-up, neuromuscular training, exercise) prevent muscle...

**Background**: Testing of muscle strength is important for assessing performance and to guide diagnosis, rehabilitation, wellness prevention programs. While isometric or isokinetic testing considered the gold standard assess strength, such tests are often not practical in settings outside research laboratory, although more advanced clinics may have these devices. One repetition maximum using elastic bands a valid alternative, but high joint loads maximal can be uncomfortable people with...

The use of ultrasound for localized fat treatment on possible psychological influences is little explored to date. Therefore, it relevant elaborate studies that include a placebo group in order measure the real effects exclusive application ultrasound.To verify influence clinical, functional, and outcomes.Thirty female participants who were candidates abdominal included randomly divided into three groups: control (CG, n = 10), experimental (EG, (PG, 10). CG did not receive any intervention....

Introdução: No universo esportivo, as análises de citocinas em resposta à prática corrida são implementadas como estratégia para dar suporte dinâmica do treinamento, com base nas necessidades individuais, a fim proporcionar condições o máximo desempenho esportivo. Objetivo: O objetivo foi investigar das durante diferentes modalidades corrida; e fornecer estimativas quantitativas alterações nesses marcadores. Métodos: Foram pesquisadas bases dados PubMed/MEDLINE, SPORTDiscus EMBASE partir dos...