A5101856313- Plant Molecular Biology Research
- Plant Reproductive Biology
- Plant nutrient uptake and metabolism
- Plant Stress Responses and Tolerance
- Plant responses to water stress
- Antimicrobial Peptides and Activities
- Animal Genetics and Reproduction
- Hippo pathway signaling and YAP/TAZ
- Cellular Mechanics and Interactions
- Plant Physiology and Cultivation Studies
- Biological Research and Disease Studies
- Cancer-related gene regulation
- Bacteriophages and microbial interactions
- Kruppel-like factors research
- Infant Nutrition and Health
- Plant tissue culture and regeneration
- Epigenetics and DNA Methylation
- Postharvest Quality and Shelf Life Management
- Cancer Research and Treatments
Southern University of Science and Technology
2017-2021
Intarcia Therapeutics (United States)
2021
Iowa State University
2015-2017
Peking University
2015-2017
University of California, Riverside
2017
Center for Life Sciences
2015
Zhejiang University
2014
Root hairs are an extensive structure of root epidermal cells and critical for nutrient acquisition, soil anchorage, environmental interactions in sessile plants. The phytohormone ethylene (ET) promotes hair growth also mediates the effects different signals that stimulate cell development. However, molecular basis ET-induced remains poorly understood. Here, we show ET-activated transcription factor ETHYLENE-INSENSITIVE 3 (EIN3) physically interacts with ROOT HAIR DEFECTIVE 6 (RHD6), a...
Mutations in the neurofibromatosis type 2 (NF2) gene that limit or abrogate expression of functional Merlin are common malignant mesothelioma. activates Hippo pathway to suppress nuclear translocation YAP and TAZ, major effectors associate with TEAD transcription factors nucleus promote genes involved cell proliferation survival. In this article, we describe discovery compounds selectively inhibit YAP/TAZ-TEAD promoted transcription, block auto-palmitoylation, disrupt interaction between...
Flowering is a highly orchestrated and extremely critical process in plant's life cycle. Previous study has demonstrated that SUPPRESSOR OF OVEREXPRESSION CONSTANS 1 (SOC1) FLOWERING LOCUS T (FT) integrate the gibberellic acid (GA) signaling pathway vernalization regulating flowering time, but detailed molecular mechanisms remain largely unclear. In GA pathway, DELLA proteins are group of master transcriptional regulators, while C (FLC) core repressor down-regulates expression SOC1 FT. Here,...
Significance Plant hormones widely regulate reprogramming of stereotypic cell specifications for plants to prevail in ever-changing environments. The well-known observation that ethylene (ET) specifically promotes root hair formation from the N-position epidermal cells provides an excellent model dissect how such reprograming events are regulated at molecular level. This work uncovers a mechanism wires ET signaling with specification cascade. Unexpectedly, we found well-recognized master...
DNA methylation is associated with gene silencing in eukaryotic organisms. Although pathways controlling the establishment, maintenance and removal of are known, relatively little understood about how influences expression. Here we identified a METHYL-CpG-BINDING DOMAIN 7 (MBD7) complex Arabidopsis thaliana that suppresses transcriptional two LUCIFERASE (LUC) reporters via mechanism largely downstream methylation. mutations components MBD7 resulted modest increases concomitant decreased LUC...
Vernalization is an essential process by which many temperate plant species acquire competence for flowering. Brachypodium distachyon a model grasses including cool-season forage and turfgrasses cereals. Grasses with spring growth habit do not require vernalization flowering are typically less winter hardy. Yet the connection between freezing tolerance remain unclear. The diverse requirement of vernation make it ideal choice studying relationship tolerance. Here, we isolated analyzed spatial...
Developmental and environmental cues induce Ca2+ fluctuations in plant cells. Stimulus-specific spatial-temporal patterns are sensed by cellular binding proteins that initiate signaling cascades. However, we still know little about how stimulus specific signals generated. The specificity of a signal may be attributed to the sophisticated regulation activities channels and/or transporters response given stimulus. To identify these components understand their functions, it is crucial use...
Developmental and environmental cues induce Ca2+ fluctuations in plant cells. Stimulus-specific spatial-temporal patterns are sensed by cellular binding proteins that initiate signaling cascades. However, we still know little about how stimulus specific signals generated. The specificity of a signal may be attributed to the sophisticated regulation activities channels and/or transporters response given stimulus. To identify these components understand their functions, it is crucial use...